In situ redox-oxidation polymerization for magnetic core-shell nanostructure with polydopamine-encapsulated-Au hybrid shell

Peripheral nerve injury is a common and complicated traumatic disease in clinical neurosurgery. With the rapid advancement and development of medical technologies, novel tissue engineering provides alternative therapies such as nerve conduit transplantation. It has achieved significant outcomes. The scaffold surface modification is vital to the reconstruction of a pro-healing interface. Polydopamine has high chemical activity, adhesion, hydrophilicity, hygroscopicity, stability, biocompatibility, and other properties. It is often used in the surface modification of biomaterials, especially in the peripheral nerve regeneration. The present review discusses that polydopamine can promote the adhesion, proliferation, and differentiation of neural stem cells and the growth of neuronal processes. Polydopamine is widely used in the surface modification of nerve conduits and has a potential application prospect of repairing peripheral nerve injury. Polydopamine-modified scaffolds are promising in the peripheral nerve tissue engineering.

show abstract

“…PDA coatings in water solutions often possess excellent mechanical strength and structural stability (Shen et al, 2015;Fang et al, 2019).…”

Section: Stability Of Pdamentioning

confidence: 99%

Applications of Polydopamine-Modified Scaffolds in the Peripheral Nerve Tissue Engineering

Yan

Liao

et al. 2020

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

“…Frens et al improved this method further by varying different parameters, and produced different sizes of AuNPs successfully from 15 nm to 150 nm [37]. The literature reveals the synthesis of AuNPs using commercially available HAuCl 4 powders [38][39][40][41]. However, in the markets, these available precursors are very expensive to make AuNPs for scale-up production.…”

Section: Introductionmentioning

confidence: 99%

Low-cost synthesis of AuNPs through ultrasonic spray pyrolysis

Tiyyagura

Majerič

Anžel

et al. 2020

Mater. Res. Express

View full text Add to dashboard Cite

The present research informs about the synthesis of gold nanoparticles (AuNPs) through Ultrasonic Spray Pyrolysis (USP), which were collected in ethanol with 0.1% Polyvinylpyrrolidone (PVP). Initially, the research focused on two precursors, where the first represented a homemade H-HAuCl 4 , completed in our own laboratory through the chlorine gas method by using HCl and KMnO 4 , and the second was the commercial C-HAuCl 4 , prepared by using Gold (III) chloride tetrahydrate powder and deionised water. The goal was to find any potential precursor differences and their influences on the later use for AuNPs synthesis through USP using almost the same parameters. In the first step of research it was determined that the H-HAuCl 4 precursor was similar to C-HAuCl 4 in chemical composition, surface tension and pH value. This finding represented the starting point for being able to use H-HAuCl 4 in the USP for AuNPs' synthesis. In the second step, AuNPs were synthesised from both types of precursors. Afterwards, characterisation of some functional properties by FTIR and UVvis techniques was done directly for H-and C-AuNPs in the collecting media. For SEM/EDX and TEM microscopy both types of H-and C-AuNPs were dried, and observation revealed that the morphology, shape and size distribution of dried AuNPs were very similar. Based on the performed laboratory research, it could be concluded that prepared H-AuNPs could represent a new and lowcost effective solution for future USP transfer onto the industrial level, not only in in the process itself, but also in the field of Low-cost Precursor Preparation.Abbreviations

show abstract

“…Because the average size of the Au nanocrystals is relatively smaller than the Ag nanocrystals, the uniform coverage of the Au nanocrystals was achieved in the Fe 3 O 4 @PDA/Au/PDA nanospheres. Previously, we developed a one-step method to synthesize Fe 3 O 4 @PDA/Au/PDA nanospheres via the in situ reduction of HAuCl 4 to Au nanocrystals and polymerization of dopamine [ 24 ]. However, the Fe 3 O 4 @PDA/Ag/PDA nanospheres cannot be obtained and the Ag nanocrystals are seriously aggregated because of the Van der Waals force and the large specific surface area.…”

Section: Resultsmentioning

confidence: 99%

“…First, magnetic Fe 3 O 4 nanoparticles were synthesized by a solvothermal reaction method [ 24 ]. Typically, FeCl 3 ·6H 2 O (1.08 g) and NaAc (4.0 g) were dissolved in 40 mL of ethylene glycol solution.…”

Section: Methodsmentioning

confidence: 99%

Hybrid Polydopamine/Ag Shell-Encapsulated Magnetic Fe3O4 Nanosphere with High Antibacterial Activity

Fang

Zhang

et al. 2020

Materials

Self Cite

View full text Add to dashboard Cite

The bacteria, which usually contaminate water environment, often cause terrible infectious diseases thus seriously threaten people’s health. To meet the increasing requirement of the public health care, an easily separable nanomaterial with sustainable anti-bacteria performance is required. This work reports a Fe3O4@PDA/Ag/PDA core-shell nanosphere in which the Ag nanocrystals immobilized on the magnetic carrier are protected by an external polydopamine (PDA) layer. The magnetic hybrid nanospheres are constructed by a tunable coating method and the particle parameters can be effectively controlled by the experimental condition. The antibacterial potential of the nanospheres is evaluable by using the Staphylococcus aureus and Escherichia coli as the models. The results indicate the Fe3O4@PDA/Ag/PDA core-shell nanospheres have a high antibacterial performance by measuring the minimum inhibitory concentration and the minimum bactericidal concentration. Finally, the product is expected to have a sustainable activity because the protecting PDA layer reduce the releasing rate of the Ag+ ions and the materials can be magnetically recovered from the media after the disinfection procedure.

show abstract

In situ redox-oxidation polymerization for magnetic core-shell nanostructure with polydopamine-encapsulated-Au hybrid shell

Cited by 61 publications

References 40 publications

Applications of Polydopamine-Modified Scaffolds in the Peripheral Nerve Tissue Engineering

Applications of Polydopamine-Modified Scaffolds in the Peripheral Nerve Tissue Engineering

Low-cost synthesis of AuNPs through ultrasonic spray pyrolysis

Hybrid Polydopamine/Ag Shell-Encapsulated Magnetic Fe3O4 Nanosphere with High Antibacterial Activity

Contact Info

Product

Resources

About