In situ observation of fracture behavior of canine cortical bone under bending

Lin, Zilan; Xu, Zhi-Hui; An, Yuehuei H.; Li, Xiaodong

doi:10.1016/j.msec.2016.01.061

Cited by 23 publications

(15 citation statements)

References 46 publications

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“…The microstructure is clearly responsible for this: secondary osteons, which exist at this scale (Fig. b), act as barriers to crack growth . Thus, as is also well known in metals and other materials, fatigue cracks grow relatively quickly until they meet these barriers, at which stage they pass through a minimum growth rate .…”

Section: Repair Of Microdamage Through Remodellingmentioning

confidence: 72%

“…3b), act as barriers to crack growth. 30,31 Thus, as is also well known in metals and other materials, fatigue cracks grow relatively quickly until they meet these barriers, at which stage they pass through a minimum growth rate. 32 So if one were designing a repair process for this material, one would naturally choose it to operate around this length scale: operating at a larger scale would be risky because the cracks would then be growing much faster, but operating at a smaller scale would be a poor use of resources because one would be repairing many cracks that will never grow to cause failure.…”

Section: R E P a I R O F M I C R O D A M A G E T H R O U G H R E M O mentioning

confidence: 89%

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Self‐healing materials: what can nature teach us?

Dooley

Taylor

2017

Fatigue Fract Eng Mat Struct

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Natural materials such as bone and insect cuticle are capable of self‐repair, a facility that greatly increases their durability and safe working stress. Some engineering materials have also been designed to be self‐healing, although currently they cannot match the performance of natural materials as regards the efficiency and longevity of the healing process. In this paper, we review the state of the art regarding these two types of materials. We discuss the role of fracture mechanics in the development of theoretical models of self‐healing; we identify certain crucial parameters that make natural materials successful and discuss how these lessons can be applied to improve the performance of self‐healing materials for engineering applications.

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Section: Repair Of Microdamage Through Remodellingmentioning

confidence: 72%

Section: R E P a I R O F M I C R O D A M A G E T H R O U G H R E M O mentioning

confidence: 89%

Self‐healing materials: what can nature teach us?

Dooley

Taylor

2017

Fatigue Fract Eng Mat Struct

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“…It is therefore reasonable to consider that OSA is associated with genetic predisposition by transmission of mutated alleles in breeds with phylogenetic proximity. Moreover, it has been demonstrated that the OSA in the Scottish Deerhounds is compatible with a dominant autosomal gene segregation with a penetrance of 0.67 and is governed primarily by a single genetic variant, which we can call a genetic risk factor 18 .…”

Section: Introductionmentioning

confidence: 99%

Evaluations of phylogenetic proximity in a group of 67 dogs with osteosarcoma: a pilot study

Virgilio¹,

Caraty²,

Hassoun³

et al. 2020

JVHC

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Aim of the Research The aim of this study is to analyze a group of dogs of different breeds affected by osteosarcoma (OSA), to document any prevalence of this primary bone neoplasia in breeds that are phylogenetically close and to help with further research human medicine, as a model of study for prevalence and epidemiology of human OSA in multiple populations. Study Design Pilot study from two canine surgery databases between 2002 and 2013. Materials and Methods Breeds were classified in groups based on their phylogenetical proximity. Differences in prevalence of OSA between breeds and groups were evaluated with a permutation test. For each breed and each group, a ranking was made by calculating 95 % confidence intervals and counting the no-overlapping between breeds and groups. The relation between the dogs’ heights and the prevalence of OSA was analyzed using a logistic regression between the disease status and dog size. Results A total of 67 dogs with OSA, in 26 different breeds were included. Ten breeds were overrepresented and, the majority of these, were classified in 2 predisposed groups phylogenetically close to each other. The prevalence of OSA was associated with the dogs’ height within predisposed breeds, but, in general, taller breeds were not the most affected. Conclusions and Clinical Relevance In this study, despite the small number of dogs, we observed that the most commonly affected breeds with OSA are phylogenetically closely related. This highlights the importance of genetics in the aetiology of canine OSA . In this preliminary study, indications are given on breeds, samples and genome locations to be further investigated. This could allow identification of pathogenic alleles in dogs, and potentially in humans. Furthermore this pilot research can represent a model of epidemiologic study of human OSA.

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“…Van Paepegem et al [24] used bending fatigue rig for composite materials where fretting action can be considered between sample and fixed joint. Notable reviews and experiments were carried out on wear, fatigue [25][26][27][28][29][30][31][32][33][34][35][36][37][38] as well as fretting fatigue [23,[39][40][41][42][43][44][45][46][47][48][49] However, relatively less on bending accelerated fretting fatigue [22,[50][51][52]. Considering all above mentioned parameters with conditions, some perfect attributes [53] of fretting fatigue test rigs (FFTR) must have Versatility to various dimensions and stiffness of the samples and fretting pads; Possibility to perform different states of load (constant or alternating load); Scope to create fretting fatigue mechanism by recording the information from various tried materials that could be applied to different model to foresee the fatigue life; Accessibility to gauge fretting stresses and strains; Minimal cost of setup to perform a few tests at the same time; Flexibility of load recurrence.…”

Section: Introductionmentioning

confidence: 99%

On the diversity in design for different bending fretting fatigue mechanism

2019

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Fretting fatigue has emerged as the center of interest for research in recent decades due to its high importance in real application field. Despite this advancement, comparatively few experiments as well as studies have been accomplished on bending fretting fatigue. Researchers either developed new test rigs or accepted a conventional concept since there exists no specific, standalone and standard test rig. However, as it is difficult to compare each work with others, the increasing number of test rigs are not suitable to ensure the justified results under conditional circumstance. This article classified the existing bending fretting fatigue test rigs depending on the variable parameters like fretting and loading actions. It can be mentioned that reciprocating fretting fatigue test rigs have more diversities as compared to rotary fretting fatigue test rigs due to the advantages of variable loading values, displacement controlling, fretting damage pre-determination and other desirable purposes. This article might be useful as a state of art for future contributions of the modern technology in industrial applications.

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In situ observation of fracture behavior of canine cortical bone under bending

Cited by 23 publications

References 46 publications

Self‐healing materials: what can nature teach us?

Self‐healing materials: what can nature teach us?

Evaluations of phylogenetic proximity in a group of 67 dogs with osteosarcoma: a pilot study

On the diversity in design for different bending fretting fatigue mechanism

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