In-situ determination of time-dependent alginate-hydrogel formation by mechanical texture analysis

Stößlein, Sebastian; Grunwald, Ingo; Stelten, Johannes; Hartwig, Andreas

doi:10.1016/j.carbpol.2018.10.056

Cited by 29 publications

(22 citation statements)

References 38 publications

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“…The latter is one of the most widespread natural PS derived mainly from brown algae of the genera Laminaria, Ascophyllum, and Fucus. Alginates belong to the family of linear copolymers and consist of residues of β-d-mannuronic and α-l-guluronic acids [6,[23][24][25][26] (Figure 1). Alginates are mixed Na and / or K, Ca and Mg water-soluble salts of alginic acid.…”

Section: Alginatesmentioning

confidence: 99%

Marine Algae Polysaccharides as Basis for Wound Dressings, Drug Delivery, and Tissue Engineering: A Review

Кузнецова

Andryukov

Беседнова

et al. 2020

JMSE

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The present review considers the physicochemical and biological properties of polysaccharides (PS) from brown, red, and green algae (alginates, fucoidans, carrageenans, and ulvans) used in the latest technologies of regenerative medicine (tissue engineering, modulation of the drug delivery system, and the design of wound dressing materials). Information on various types of modern biodegradable and biocompatible PS-based wound dressings (membranes, foams, hydrogels, nanofibers, and sponges) is provided; the results of experimental and clinical trials of some dressing materials in the treatment of wounds of various origins are analyzed. Special attention is paid to the ability of PS to form hydrogels, as hydrogel dressings meet the basic requirements set out for a perfect wound dressing. The current trends in the development of new-generation PS-based materials for designing drug delivery systems and various tissue-engineering scaffolds, which makes it possible to create human-specific tissues and develop target-oriented and personalized regenerative medicine products, are also discussed.

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Section: Alginatesmentioning

confidence: 99%

Marine Algae Polysaccharides as Basis for Wound Dressings, Drug Delivery, and Tissue Engineering: A Review

Кузнецова

Andryukov

Беседнова

et al. 2020

JMSE

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“…co-polymers composed of the polysaccharides β-D-Mannuronic acid (M) and α-L-Gluloronic acid (G) (Axpe and Oyen, 2016). Alginates contain blocks of G residues, blocks of M residues, and alternating M and G residues (Stößlein et al, 2019). The M and MG residues of the co-polymer have been shown to increase flexibility, whereas the G residues increase rigidity and the capacity for gelation (Axpe and Oyen, 2016).…”

Section: Plant-derived Biomaterials Alginatementioning

confidence: 99%

Plant-Derived Biomaterials: A Review of 3D Bioprinting and Biomedical Applications

et al. 2019

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The pursuit of appropriate, biocompatible materials is one of the primary challenges in translational bioprinting. The requirement to refine a biomaterial into a bioink places additional demands on the criteria for candidate biomaterials. The material must enable extrusion as a liquid bioink and yet be capable of maintaining its shape in the post-printing phase to yield viable tissues, organs and biological materials. Plant-derived biomaterials show great promise in harnessing both the natural strength of plant microarchitecture combined with their natural biological roles as supporters of cell growth. The aim of this review article is to outline the most widely used biomaterials derived from land plants and marine algae: nanocellulose, pectin, starch, alginate, agarose, fucoidan, and carrageenan, with an in-depth focus on nanocellulose and alginate. The properties that render these materials as promising bioinks for three dimensional bioprinting is herein discussed alongside their potential in 3D bioprinting for tissue engineering, drug delivery, wound healing, and implantable medical devices.

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“…80 Effective quantification of alginate hydrogel formation along with its mechanical strength could be dictated by external gelation process using calcium chloride (CaCl2). 81 Hence divalent cations, such as Ca 2+ and Ba 2+ , played the mastered role as crosslinking agents to transform aqueous solutions of sodium alginate to gels. The predicted interaction strength order was reported as Pb 2+ > Cu 2+ > Cd 2+ > Ba 2+ > Sr 2+ > Ca 2+ .…”

Section: Alginate Based Gelmentioning

confidence: 99%

Recent Development of Polysaccharide-Derived Hydrogel: Properties, Stimuli-Responsiveness and Bioapplications

Mukherjee

2022

Preprint

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Hydrogels are three-dimensional, hydrophilic, polymeric frameworks, constructed through diverse physical or chemical crosslinks. Recent research focuses on their physiological stimuli sensitivity enhancing bioapplications. Biopolymers with responsiveness to local environment like temperature, pH etc. form the foundation in this regard, around which all major natural processes are circulated. Polysaccharides, being most the abundant biopolymers and essential constituent of our daily food like cereals and fruits, are readily available in nature. Hence, among numerous biomacromolecules, polysaccharides are extensively used to prepare hydrogel recently. However, incorporation of certain properties to these gels through derivatization can trigger stimuli responsiveness suitable for various applications especially in biomedical field inspired from the mother nature. For example, in situ cross-linking ability may deliver an intermediate platform between solid scaffolds and saline injections through reversible or irreversible sol-gel transition. Easy injectability provides patient’s relief through reducing recovery time and inflectional hazards. Self recovery of gel within body results automatic inflammation and damage recovery of tissues. This review provides a detail impression on the synthesis of natural polysaccharide derived hydrogel network with structural classification to bulk, supramolecular, micro and nano gel. Several properties important from biomedical point such as in situ, injectable, self healing nature of these hydrogels and various physical, chemical, or biochemical stimuli-responsive characteristics are discussed further. Lastly, their major bioapplications are highlighted.

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In-situ determination of time-dependent alginate-hydrogel formation by mechanical texture analysis

Cited by 29 publications

References 38 publications

Marine Algae Polysaccharides as Basis for Wound Dressings, Drug Delivery, and Tissue Engineering: A Review

Marine Algae Polysaccharides as Basis for Wound Dressings, Drug Delivery, and Tissue Engineering: A Review

Plant-Derived Biomaterials: A Review of 3D Bioprinting and Biomedical Applications

Recent Development of Polysaccharide-Derived Hydrogel: Properties, Stimuli-Responsiveness and Bioapplications

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