In-hospital and 1-year outcomes of acute heart failure patients according to presentation (de novo vs. worsening) and ejection fraction. Results from IN-HF Outcome Registry

Heart failure with preserved ejection fraction: Refocusing on diastole

“…While symptoms at rest with acute pulmonary edema are also seen, patients with HFpEF are more likely to be seen in the ambulatory setting and less likely to be hospitalized for HF than patients with HFrEF. However, once hospitalized for HF, the cardiac risk for HFpEF is similar to that of HFrEF [22,23].…”

New onset heart failure — Clinical characteristics and short-term mortality. A RICA (Spanish registry of acute heart failure) study

“…Current guidelines have started to realize the differential characteristics of HF patients whose symptoms and signs develop "fast", requiring immediate medical attention, often leading to hospitalization, which is the definition of "acute HF". Patients presenting with acute HF who have not shown symptoms of HF prior to the acute episode are tagged as "de novo" or new-onset HF and contribute to a significant proportion (between 12% and 63%) of all acute HF episodes patients [1,3]. It has already been described that the clinical characteristics of the acute HF episode among this subset of "new" patients more often include severe features such as acute pulmonary edema or cardiogenic shock, which result in a greater risk of morbidity and mortality [4][5][6].…”

“…Abbreviations: BMI: body-mass index; SBP: systolic blood pressure; MDRD: Modification of Diet in Renal Disease formula; BNP: brain natriuretic peptide; LVEF: left-ventricle ejection fraction; NHYA: New York Heart Association; COPD: chronic obstructive pulmonary disease. ACEI: angiotensin-converting-enzyme inhibitors; ARB: angiotensin receptor blockers.reported by Senni et al regarding 1-year all cause and cardiovascular mortality[3].…”

Palliative needs for heart failure or chronic obstructive pulmonary disease: Results of a multicenter observational registry

“…However, our national contemporary data indicate that six-month mortality is approximately 20% for patients hospitalized for worsening HF with reduced ejection fraction in cardiology units [51] and 15% for those admitted with a severe COPD exacerbation [52].…”