Imunidade relacionada à resposta alérgica no início da vida

Correa, Joaquina M.M.; Zuliani, Antonio Carlos

doi:10.1590/s0021-75572001000600005

Cited by 7 publications

(10 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Foi postulado que fatores genéticos e ambientais nos primeiros anos de vida podem ser determinantes no tipo de resposta imunológica futura 21,27 .…”

Section: Discussionunclassified

Evaluation of atopy among mouth-breathing pediatric patients referred for treatment to a tertiary care center

Barros¹,

Becker²,

Pinto³

2006

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objective: A mouth breather is someone who uses his/her oral cavity as main airway during breathing. This is a syndrome with several etiologies, but allergic rhinitis plays a key role due to its high prevalence. The aim of this study was to assess the presence of atopy among mouth-breathing patients referred to a tertiary care center in the metropolitan region of Belo Horizonte, Brazil.Methods: Cross-sectional, descriptive study carried out at Hospital das Clínicas of Universidade Federal de Minas Gerais. Patients aged 2 to 12 years, admitted between November 2002 and April 2004, were included. Parents or surrogates completed a comprehensive questionnaire, and patients were submitted to a skin test for inhalant allergens. A total of 140 patients participated in the study. Those with a positive result for at least one allergen were regarded as atopic. The statistical analyses were made using SPSS, with univariate analyses followed by logistic regression.Results: Of 140 patients, 44.3% (62/140) obtained positive results on the allergic test. Mites were the most predominant allergens, with a positive rate of 100% among atopic patients. In the multivariate analysis, atopy was significantly associated with the male sex (p = 0.05), presence of asthma (p = 0.014), lower number of people sleeping in the same room with the patient (p = 0.005), absence of passive smoking (p = 0.005) and absence of sleep apnea (p = 0.003). Conclusion:The high prevalence of positive results on the allergic test highlights the importance of allergologic investigation in mouth-breathers, since allergy has specific treatments that may reduce morbidity in these patients when properly used.J Pediatr (Rio J). 2006;82(6):458-64: Atopy, allergic rhinitis, mouth-breathers, allergen, dust mites. ResumoObjetivo: Respirador bucal é o indivíduo que utiliza a cavidade oral como principal via aérea durante a respiração. Trata-se de síndrome de múltiplas etiologias, dentre as quais a rinite alérgica merece destaque por sua alta prevalência. Este trabalho teve como objetivo avaliar a presença de atopia entre respiradores bucais encaminhados a serviço de referência da região metropolitana de Belo Horizonte. Resultados: Entre os 140 pacientes, 44,3% (62/140) tiveram teste alérgico positivo. Ácaros foram os alérgenos predominantes, apresentando positividade em 100% dos atópicos. Em análise multivariada, atopia esteve significativamente associada ao sexo masculino (p = 0,05), presença de asma (p = 0,014), menor número de pessoas dormindo no mesmo cômodo que o paciente (p = 0,005), ausência de tabagismo passivo (p = 0,005) e ausência de apnéia noturna (p= 0,003). MétodosConclusão: A alta prevalência de positividade no teste alérgico enfatiza a importância da investigação alergológica em respiradores bucais, pois a alergia tem formas específicas de tratamento que podem reduzir a morbidade desses pacientes quando adequadamente utilizadas. Evaluation of atopy among mouth-breathing pediatric patients referred for treatment to a tertiary care center Introduç...

show abstract

“…Foi postulado que fatores genéticos e ambientais nos primeiros anos de vida podem ser determinantes no tipo de resposta imunológica futura 21,27 .…”

Section: Discussionunclassified

Evaluation of atopy among mouth-breathing pediatric patients referred for treatment to a tertiary care center

Barros¹,

Becker²,

Pinto³

2006

J Pediatr (Rio J)

View full text Add to dashboard Cite

show abstract

“…Exclusive breast‐feeding for a prolonged period is a confirmed protective factor against the development of allergic manifestations (1–9). This protective factor is stronger when exclusive breast‐feeding is practiced for a minimum period from 3 to 6 months (1, 2, 5–9).…”

mentioning

confidence: 99%

Exposure to maternal smoking in the first year of life interferes in breast‐feeding protective effect against the onset of respiratory allergy from birth to 5 yr

Guedes

Souza

2009

Pediatric Allergy Immunology

View full text Add to dashboard Cite

The aim of this study was to evaluate the interaction between the exclusive breast‐feeding protective effect and the exposure to tobacco smoke at domicile in the first year of life, on the onset of respiratory allergy (asthma and rhinitis) in children until 5 yr of age. This is prospective cohort study, observational, institutional based. Three hundred children born in a public hospital of Salvador‐Bahia (Brazil) were followed from birth to 5 yr of age. Data from 268 children at 60 months of life were analyzed. Occurrence of allergic symptoms were studied and correlated with gender, allergic relatives in first degree, exclusive breast‐feeding duration, smoking mother, and presence of other smoker at home, considering the first year of life. Exclusive breast‐feeding for at least 6 months showed a protection effect against the onset of respiratory allergy in children from birth to 5 yr (p < 0.05); odds ratio (OR): 0.33 (95% CI: 0.18–0.59). Breast‐fed children for less then 6 months compared with those breast‐fed for 6 months or more, presented a higher risk (OR: 2.34–95% CI: 1.4–3.74) for developing allergic respiratory symptoms just to 5 yr. The protective effect of exclusive prolonged breast‐feeding on the onset of respiratory allergy in children from birth until 5 yr was lost when their mothers were smokers (OR: 2.50–95% CI 1.19–5.19). Therefore, the protective effect of breast‐feeding in the first year of life on the onset of allergic symptoms until the age of 5 yr was confirmed. This study proposes a confounding effect of maternal smoking on this protection, exposed by a higher risk for present allergic symptoms until the age of 5 yr, in children exclusively breast‐fed for 6 months or more, when their mothers smoked.

show abstract

“…Nestas áreas, a forma desordenada como vem se dando a urbanização faz com que aglomerados urbanos cresçam de modo caótico, com infra-estrutura física, habitação e serviços altamente vulneráveis 19 . Nesses ambientes, as infecções gastrintestinais (parasitárias, bacterianas e virais) são consideradas, por alguns autores 17 , como fatores protetores à resposta imune Th1 e, conseqüentemente, funcionando como mecanismos reguladores para a menor ocorrência de asma na população mais exposta àquelas infecções.…”

Section: Características Demográficasunclassified

“…De outro modo, essa mesma associação não foi observada com os outros membros parentais das crianças, adultos (pais, avós e tios), o que, independente dos fatores genéti-cos e familiais, até certo modo pode ser explicado pelas diferenças no tipo e na intensidade da exposição ambiental, entre outros fatores, próprios de cada faixa etária 14,17,18 .…”

Section: Características Demográficasunclassified

Asma e ascaridíase em crianças de 2 a 10 anos de um bairro de periferia

Silva¹,

Andrade²,

Tavares-Neto³

2003

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

ResumoObjetivo: avaliar a associação entre asma e ascaridíase em crianças do bairro Pedregal, da cidade de Campina Grande (Paraí-ba), onde são baixos os indicadores de desenvolvimento humano. Material e método: foi aplicado o questionário padrão doInternational Study of Asthma and Allergies in Childhood (ISAAC), em 1.095 crianças, mas apenas 742 o responderam e entregaram a amostra fecal para realização do exame parasitológico. A faixa etária das 742 crianças incluídas no estudo transversal foi de 2 a 10 anos de idade. A associação entre asma e ascaridíase foi estudada pelo índice Kappa. As análises das variáveis demográficas e clínicas, comparando os dois grupos, foram realizadas pelo teste do quiquadrado (χ 2 ) ou o teste t de Student para os dados quantitativos (contínuos).Resultados: nas 742 crianças, as proporções dos sexos foram semelhantes: 51,9% (n=385) do masculino e 48,1% (n=357) do feminino. Nessas crianças, a prevalência de asma foi de 59,7% (n=443) e da ascaridíase de 56,3% (n=418), sendo semelhante (χ 2 =0,27; p>0,60) a freqüência de asma no grupo portador de ascaridíase (60,5%) ou sem essa helmintíase (58,6%).Conclusão: apesar da elevada freqüência dos agravos estudados, não há aparente associação entre asma e ascaridíase na população estudada.J Pediatr (Rio J) 2003;79(3):227-32: asma, ascaridíase, criança, prevalência. AbstractObjective: to assess the relation between children with asthma and ascariasis in the low income neighborhood of Pedregal, in Campina Grande (Paraíba, Brazil). Material and method: the International Study of Asthma andAllergies in Childhood (ISSAC) standard questionnaire was distributed to 1,095 children but only 742 of them answered it and provided stool samples for parasite examination. The cross-sectional study included those 742 children, whose age ranged from 2 to 10 years. The association between asthma and ascariasis was studied through Kappa rating. Demographic and clinic variants comparing the two groups were analyzed by chi-square test (χ 2 ) or t Student test.Results: among the 742 children analyzed, 51.9% (385) were males and 48.1% (357) females. The prevalence of asthma was 59.7% (443) and that of ascariasis was 56.3% (418). The frequency of asthma in the ascariasis group (60.5%) was similar (χ 2 = 0.27, p > 0.06) to the frequency of asthma in the non-infected group (58.6%).Conclusion: despite the high prevalence of the diseases studied, there is no apparent relation between asthma and ascariasis in the population studied.J Pediatr (Rio J) 2003;79(3):227-32: asthma, ascariasis, children, prevalence. Asma e ascaridíase em crianças de 2 a 10 anos de um bairro de periferia Asthma and ascariasis in children aged two to ten living in a low income suburbMaria Teresa Nascimento Silva 1 , Jacy Andrade 2 , José Tavares-Neto 3 Introdução A asma é uma doença crônica muito freqüente em crianças, traduzida pelos episódios de sibilância pulmonar, e a sua gravidade vem aumentando em vários países do mundo 1 . Como se sabe, a predisposição genética é o fator de risco mais f...

show abstract

Imunidade relacionada à resposta alérgica no início da vida

Cited by 7 publications

References 27 publications

Evaluation of atopy among mouth-breathing pediatric patients referred for treatment to a tertiary care center

Evaluation of atopy among mouth-breathing pediatric patients referred for treatment to a tertiary care center

Exposure to maternal smoking in the first year of life interferes in breast‐feeding protective effect against the onset of respiratory allergy from birth to 5 yr

Asma e ascaridíase em crianças de 2 a 10 anos de um bairro de periferia

Contact Info

Product

Resources

About