Improving Safety of MRI in Patients with Deep Brain Stimulation                    Devices

Boutet, Alexandre; Chow, Chung‐Wai; Narang, Keshav; Elias, Gavin J B; Neudorfer, Clemens; Germann, Jürgen; Ranjan, Manish; Loh, Aaron; Martin, Alastair J.; Kucharczyk, Walter; Steele, Christopher; Hancu, Ileana; Rezai, Ali R.; Lozano, Andrés M.

doi:10.1148/radiol.2020192291

Cited by 47 publications

(43 citation statements)

References 102 publications

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“…First, the SAR value of the DTI sequence performed was only 0.34 ± 0.02 W/kg, which is lower than the recommended threshold level of 0.4 W/kg [ 19 ]. The SAR values of T1-weighted and T2-weighted sequences for the postoperative MR scanning have been proven safe in previous studies [ 31 ]. However, research on the safety of DTI sequences with DBS device implantation remains limited.…”

Section: Discussionmentioning

confidence: 99%

“…There have been concerns regarding the effect of MRI on surgically implanted metal electrodes due to possible heating and displacement of the metal components by the magnet [31,[34][35][36]. Nevertheless, postoperative DTI is a useful imaging modality for patients with PD or other movement disorders, since it has the capability to show both the electrode position and the white matter tracts on the same image.…”

Section: Artifacts In the Dti Image With A Dbs Devicementioning

confidence: 99%

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Mapping Motor Pathways in Parkinson’s Disease Patients with Subthalamic Deep Brain Stimulator: A Diffusion MRI Tractography Study

Zhang

et al. 2022

Neurol Ther

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Section: Discussionmentioning

confidence: 99%

Section: Artifacts In the Dti Image With A Dbs Devicementioning

confidence: 99%

Mapping Motor Pathways in Parkinson’s Disease Patients with Subthalamic Deep Brain Stimulator: A Diffusion MRI Tractography Study

Zhang

et al. 2022

Neurol Ther

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“…Considering that greater magnetic field strengths can cause the heating of DBS devices and subsequent brain damage, low strength MRI is much safer for scanning post-DBS neuroimaging data [ 61 ]. Researchers have been trying to eliminate this effect by optimizing MRI equipment and DBS devices [ 62 ] and it might be necessary to conduct studies with better tools and a larger cohort in the future to reach a more precise, as well as stable, result.…”

Section: Discussionmentioning

confidence: 99%

A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Ruan

Wang

et al. 2022

Brain Sciences

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Obsessive-compulsive disorder (OCD) is a chronic and debilitating mental disorder. Deep brain stimulation (DBS) is a promising approach for refractory OCD patients. Research aiming at treatment outcome prediction is vital to provide optimized treatments for different patients. The primary purpose of this systematic review was to collect and synthesize studies on outcome prediction of OCD patients with DBS implantations in recent years. This systematic review (PROSPERO registration number: CRD42022335585) followed the PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis) guidelines. The search was conducted using three different databases with the following search terms related to OCD and DBS. We identified a total of 3814 articles, and 17 studies were included in our review. A specific tract confirmed by magnetic resonance imaging (MRI) was predictable for DBS outcome regardless of implant targets, but inconsistencies still exist. Current studies showed various ways of successful treatment prediction. However, considering the heterogeneous results, we hope that future studies will use larger cohorts and more precise approaches for predictors and establish more personalized ways of DBS surgeries.

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“…Around 70% of patients will need an MRI within 10 years of DBS implantation due to comorbidities or device complications (Falowski et al, 2016). MRI-related injuries in the early 2000s in DBS patients led to a considerable number of MRI safety studies being conducted and establishment of MRI guidelines by hardware vendors (Boutet et al, 2020). Fortunately, MRI compatibility of newer devices is improving with almost all currently available IPGs being full-body 1.5 Tesla MRI-conditional (Figure 1).…”

Section: Mri Compatibilitymentioning

confidence: 99%

Implantable Pulse Generators for Deep Brain Stimulation: Challenges, Complications, and Strategies for Practicality and Longevity

Sarica

Iorio-Morin

Aguirre-Padilla

et al. 2021

Front. Hum. Neurosci.

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Deep brain stimulation (DBS) represents an important treatment modality for movement disorders and other circuitopathies. Despite their miniaturization and increasing sophistication, DBS systems share a common set of components of which the implantable pulse generator (IPG) is the core power supply and programmable element. Here we provide an overview of key hardware and software specifications of commercially available IPG systems such as rechargeability, MRI compatibility, electrode configuration, pulse delivery, IPG case architecture, and local field potential sensing. We present evidence-based approaches to mitigate hardware complications, of which infection represents the most important factor. Strategies correlating positively with decreased complications include antibiotic impregnation and co-administration and other surgical considerations during IPG implantation such as the use of tack-up sutures and smaller profile devices.Strategies aimed at maximizing battery longevity include patient-related elements such as reliability of IPG recharging or consistency of nightly device shutoff, and device-specific such as parameter delivery, choice of lead configuration, implantation location, and careful selection of electrode materials to minimize impedance mismatch. Finally, experimental DBS systems such as ultrasound, magnetoelectric nanoparticles, and near-infrared that use extracorporeal powered neuromodulation strategies are described as potential future directions for minimally invasive treatment.

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Improving Safety of MRI in Patients with Deep Brain Stimulation Devices

Cited by 47 publications

References 102 publications

Mapping Motor Pathways in Parkinson’s Disease Patients with Subthalamic Deep Brain Stimulator: A Diffusion MRI Tractography Study

Mapping Motor Pathways in Parkinson’s Disease Patients with Subthalamic Deep Brain Stimulator: A Diffusion MRI Tractography Study

A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Implantable Pulse Generators for Deep Brain Stimulation: Challenges, Complications, and Strategies for Practicality and Longevity

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