Improving knowledge on vaccine storage management in general practices: Learning effectiveness of an online-based program

Thielmann, Anika; Puth, Marie-Therese; Weltermann, Birgitta

doi:10.1016/j.vaccine.2020.09.049

Cited by 11 publications

(14 citation statements)

References 18 publications

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“…In April 2021, the Institute for Safe Medication Practices (ISMP) indicated that 20% of COVID-19 vaccine errors reported were due to lower- or higher-than-authorized dosage [ 38 ]. Some studies regarding the quality and service delivery of routine non-COVID-19 immunization processes have reported that challenges concerning the storage of vaccines remain a major limitation in the vaccine administration process [ 27 , 39 , 40 , 41 , 42 ]. A study on vaccine administration errors in a large academic center in the United States where over 1.4 million vaccines were administered reported that unfamiliar procedures and variations in procedures associated with vaccine administration increased the likelihood of vaccine administration errors [ 43 ].…”

Section: Discussionmentioning

confidence: 99%

Qualitative Conceptual Content Analysis of COVID-19 Vaccine Administration Error Inquiries

et al. 2023

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The launch of the COVID-19 vaccination program was the largest vaccination campaign in U.S. history, with an unprecedented demand for vaccine and new vaccination providers, warranting significant education and communication efforts. NIP-INFO (nipinfo@cdc.gov) is the Centers for Disease Control and Prevention’s (CDC’s) immunization inquiry response service, and it receives inquiries for COVID-19 and routine non-COVID vaccines. A qualitative analysis of NIP-INFO’s content was performed to better characterize and understand some of the knowledge gaps and reasons that COVID-19 vaccine administration errors occur. A total of 734 COVID-19 vaccine administration error inquiries were received between January 2021 and April 2022. The most frequent inquiries related to storage (n = 191; 26.0%), incorrect dosage or product (n = 190; 25.9%), unauthorized age group (n = 108; 14.7%), and schedule (n = 105; 14.3%). Training and communication strategies are imperative to ensure proper vaccine administration and build and maintain vaccine confidence.

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Section: Discussionmentioning

confidence: 99%

Qualitative Conceptual Content Analysis of COVID-19 Vaccine Administration Error Inquiries

et al. 2023

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“…Also, a high prevalence of additional storage deficits was documented, e.g., no use of bins (81.3%), no thermometers in the center of refrigerators (54.0%), vaccines boxes with contact to outer walls (46.3%), refrigerator unsuitable for vaccine storage (44.6%), and unwrapping of vaccines (31.1%) [ 26 ]. Access to the eLearning program KeepCoool significantly increased the knowledge of GPs and practice assistants: the mean number of correct answers was 5.6 of 11 answers at baseline and increased to 9.8 after program participation (p<0.001) [ 27 ].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of the online-eLearning program KeepCoool at improving the vaccine cold chain in general practices

Thielmann,

Schmitz,

Welchowski

et al. 2024

PLoS ONE

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Background Protecting vaccines from freeze damage is a poorly addressed problem. We describe the effectiveness of the eLearning KeepCoool on cold chain maintenance in general practices. Methods For this intervention study, temperatures of vaccine refrigerators were logged at one-minute intervals. Personnel from practices with cold chain breaches was offered the eLearning. The primary outcome was the intervention’s effectiveness to achieve temperatures in the target range (2 to 8°C) in the sixth week (follow-up) compared to the first (baseline). Using continuous temperature data, a generalized additive model for location, scale and shape was estimated. Results The practice response rate was 38% (64 of 168). At baseline, 73% of the practices and 68% of the refrigerators (51 of 75) showed cold chain breaches. 47% of the practices (n = 22 with 24 refrigerators) participated in the eLearning (55 physicians and practice assistants). At follow-up, 17% of those refrigerators were in the target range continuously, 38% reached targets 95% of the time while always >0°C, and temperatures ≤0°C decreased by 63%. Based on 2 million temperature data, the average Euclidian distance based on regression showed a significant improvement (p<0.05). Conclusion The eLearning KeepCoool improved the practices´ vaccine cold chain. It is freely available at https://keepcoool.ukbonn.de.

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“…Furthermore, this study is expected to facilitate authors, policymakers, field implementers, expedition/logistics businessmen, and technology developers (engineers) in implementing the vaccination program. It is very important because due to the need to improve the understanding level of stakeholders on vaccine management ( Osei et al, 2019 , Yakum et al, 2015 , Mohammed et al, 2021b , Bogale et al, 2019 , Thielmann et al, 2020 , Dairo et al, 2016 , Vangroenweghe, 2017 , Thielmann et al, 2019b ). Studies have shown numerous failures in vaccine management, especially in terms of temperature in storage units and standard for distribution ( Thielmann et al, 2019b , Yauba et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

et al. 2022

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The outbreaks of infectious diseases that spread across countries have generally existed for centuries. An example is the occurrence of the COVID-19 pandemic in 2020, which led to the loss of lives and economic depreciation. One of the essential ways of handling the spread of viruses is the discovery and administration of vaccines. However, the major challenges of vaccination programs are associated with the vaccine cold chain management and cold storage facilities. This paper discusses how vaccine cold chain management and cold storage technology can address the challenges of vaccination programs. Specifically, it examines different systems for preserving vaccines in either liquid or frozen form to help ensure that they are not damaged during distribution from manufacturing facilities. Furthermore, A vaccine is likely to provide very low efficacy when it is not properly stored. According to preliminary studies, the inability to store vaccine properly is partly due to the incompetency of many stakeholders, especially in technical matters. The novelty of this study is to thoroughly explore cold storage technology for a faster and more comprehensive vaccine distribution hence it is expected to be one of the reference and inspiration for stakeholders.

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Improving knowledge on vaccine storage management in general practices: Learning effectiveness of an online-based program

Cited by 11 publications

References 18 publications

Qualitative Conceptual Content Analysis of COVID-19 Vaccine Administration Error Inquiries

Qualitative Conceptual Content Analysis of COVID-19 Vaccine Administration Error Inquiries

Effectiveness of the online-eLearning program KeepCoool at improving the vaccine cold chain in general practices

Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

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