“…However, CRET also has beneficial effects on certain emotions and improving ANS function, 16 and improves inflammation, 61,62 metabolic syndrome 63,64 and blood rheology. 65 Some evidence suggests that ET also has favorable effects on brain plasticity and cognition. 66,67 In fact, CRET involves more than just ET, and other aspects of the Phase II CRET programs involve education of the patients and their significant others, which may also be important by increasing understanding of the underlying M A N U S C R I P T…”