“…Over the past 2 decades, significant effort has been placed on improving the materials used in Li-ion batteries. These improvements have targeted increased capacity, power, and lifetime, − and they were informed by increased insight into the reactions occurring at the level of individual particles. , To fully understand the inner workings of single particles of Li-ion cathodes, multiple instrumental modalities must be coupled in order to obtain a complete picture of the consequences of irreversibility and, thus, degradation of structure and chemistry. Common degradation mechanisms involve, but are not limited to, cathode–electrolyte side reactions, competing structural transformations, , and delamination due to mechanical strain .…”