Improvement of PDMS surface biocompatibility is limited by the duration of oxygen plasma treatment

Abstract

The recent study focused on the improvement of polydimethylsiloxane (PDMS) surface biocompatibility as the most commonly used biomaterial in maxillofacial prostheses for intraoral defects. Biocompatibility enhances tissue‐prosthesis integration to prevent implant dislocation; to evaluate the parameter the study conducted at different times of oxygen plasma exposure. Scanning electron microscopy, contact angle measurement, atomic force microscopy and above all, cell cultivation—as a crucial factor in biocompatibility—carried out to investigate the samples’ characteristics. An improved PDMS biocompatibility is expected; referring to the fact that an “optimal range”—not necessarily the maximum values—of surface hydrophilicity and roughness could induce an enhanced cell attachment on the PDMS surface, an “optimum time” of O2 plasma exposure is required to meet this goal. Considering the O2 plasma setup items, the ratio of PDMS components and fabrication process in the current survey, 2.5‐min O2 plasma exposure well suited to PDMS surface cell adhesion.

Cell-membrane-inspired polymers for constructing biointerfaces with efficient molecular recognition

“…These hydrophobic surfaces are known to have considerable affinity for oil droplets in aqueous environments, that is, they adsorb proteins and lipids, and do not inhibit blood clotting reactions. [89][90][91][92][93] Essentially, research on material design from the physicochemical viewpoint of controlling surface free energy and interfacial energy, involving aspects such as simple hydrophilicity and hydrophobicity, has not succeeded in yielding anti-blood-coagulating properties.…”

Patient-specific brain arteries molded as a flexible phantom model using 3D printed water-soluble resin

“…While all of these are important, the phantom model should also be able to resemble in vivo conditions, so its material must be considered. A silicone rubber called polydimethylsiloxane (PDMS) is commonly used in phantom models since it is transparent, inert, non-toxic 11 , 12 and has an elasticity that can be tuned 13 , 14 . This is ideal for flow models that are used to conduct biological studies and/or incorporate compliant (flexible) elements.…”

Multifunctional Flexible and Wearable Sensing System Based on Optical Microfiber Interferometry

“…On the other hand polydimethylsiloxane (PDMS) is an excellent material to embeed optical microfiber due to its biocompatibility and robust mechanical stability 30,31 apart from providing mechanical stability to the microfiber which otherwise is fragile and difficult to use. PDMS incorporated optical microfiber also exhibit low loss, high-temperature steadiness with high flexibility.…”