Improvement of hemostasis in open and laparoscopically performed partial nephrectomy using a gelatin matrix-thrombin tissue sealant (FloSeal)

Kidney salvage using the fibrinogen- and thrombin-coated sponge TachoSil<SUP>®</SUP> during nephron-sparing surgery for the resection of large renal tumours

“…The efficacy of nephron-sparing surgery is often reported in relation to small, < 4 cm, low-stage localised renal cell cancers. 19 However, we report the successful performance of nephron-sparing surgery for the excision of tumours ≥ 5 cm. Pre-operatively, both patients had limited kidney function; consequently, renal preservation and even survival were not assured.…”

Adjuncts for Tissue stasis

“…121 Another report utilizing FloSeal ® during partial nephrectomy procedures found the adjunct helpful in providing immediate hemostasis. 122 FloSeal ® in both studies was noted to be particularly advantageous in laparoscopic renal procedures. Rapid, effective hemostasis was also observed when FloSeal ® was used to stop vigorous bleeding in transsphenoidal pituitary surgery.…”

Feasibility study for robotic radical prostatectomy cautery-free neurovascular bundle preservation

“…Experience with gelatin matrix hemostatic sealants in the urologic literature is growing. Richter and associates showed improvement of hemostasis in open and laparoscopic partial nephrectomy using a gelatin matrixthrombin tissue sealant 13 . In their series, 25 patients underwent partial nephrectomy followed by FloSeal application to the tumor bed before re-perfusion of the kidney.…”