Improvement of drug delivery by hyperthermia treatment using magnetic cubic cobalt ferrite nanoparticles

The effect of agarose content on the morphology, phase evolution, and magnetic properties of CoFe2O4 nanoparticles prepared by sol‐gel autocombustion method

“…In recent years, the application of nanoparticles (NPs) in magnetic hyperthermia (MH) has been attracted much attention because of its minimal side effects and natural potential in biomedical fields . The different range of AC magnetic field frequencies is applied in magnetic hyperthermia in which magnetic energy scatters to heat via relaxation loss processes and temperature increases to 41‐ 45°C which is ideal to kill cancer cells without bothering healthy cells . There are numerous kinds of nanoparticles that considerably are noticed in MH such as iron oxide (MFe 2 O 4 , M = Co, Fe, Ni, Mn,…) NPs, alloy (FeCo, FePt,…) NPs, and multifunctional NPs of a core/shell‐type .…”

Improvement of Anticancer Drug Release by Cobalt Ferrite Magnetic Nanoparticles through Combined pH and Temperature Responsive Technique

“…In our previous work, we have reported the power loss (PL∼1 W/g=1 J/s.g) of the same sample as obtained under 60 kA/m field of 600 Hz . Here, from DTA data we have the heat flow (HF) of the CFMNPs at 30 °C∼1 mW=0.001 J/s, the heating rate (HR)∼10 °C/min=10/60=1/6 °C/s and the sample's mass (m)∼10 mg=0.01 g. So, the heat required to increase the temperature 1 °C for 1 g sample is HF/(HR×m)=0.001×6/0.01 J=0.6 J, which is the specific heat of the sample.…”

“…CFMNPs were prepared by following our reported work . Briefly, ferric chloride (FeCl 3 , 6H 2 O), cobalt chloride (CoCl 2 .6H 2 O), ethylene glycol, ethanol, urea, TX‐100 and oleylamine were purchased from Sigma‐Aldrich.…”

“…To load DOX, 20 mg FA coated CFMNPs were dispersed in 5 ml of distilled water followed by addition of 200 μL sodium bicarbonate solution (0.1 M). 200 μL DOX solution (∼6.897×10 −4 M) was added to the primary solution and stirred for next 3 h. After that, the CFMNPs were isolated by magnetic separation method, washed gently with phosphate buffer saline (PBS) solution and dried …”

“…In our previous work, we have prepared CFMNPs by using surfactants like; oleylamine and Triton X‐100 (TX‐100). We obtained ∼0.96 kOe of coercivity (H C ) at 300 K. The ac hysteresis loops were measured under different field frequencies.…”