Improvement of Antioxidant and Immune Status of Atherosclerotic Rats Adrenaline and Egg-Yolks -Induced Using Cardamom-Rhizome-Ethanolic-Extract: An Initial Study of Functional Food

Winarsi, Hery; Yuniaty, Alice; Nuraeni, Indah

doi:10.1016/j.aaspro.2016.02.147

Cited by 12 publications

(11 citation statements)

References 25 publications

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“…However, a few studies have investigated its effect on humans. In atherosclerotic rats, cardamom rhizome ethanolic extract significantly increased SOD levels and decreased MDA, CRP, and IL‐6 . By reducing the synthesis of eicosanoid mediators of inflammation, a dose‐dependent anti‐inflammatory effect of cardamom oil on rats has been shown .…”

Section: Discussionmentioning

confidence: 97%

“…In atherosclerotic rats, cardamom rhizome ethanolic extract significantly increased SOD levels and decreased MDA, CRP, and IL-6. 30 By reducing the synthesis of eicosanoid mediators of inflammation, a dose-dependent anti-inflammatory effect of cardamom oil on rats has been shown. 26 In addition, by decreasing cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) expression, the anti-inflammatory activity of cardamom has been reported.…”

Section: Discussionmentioning

confidence: 99%

“…A sample size of at least 36 in each group was calculated according to the standard deviation of high‐sensitivity (hs)‐CRP in a similar study in the following order ( α = 0.05; power = 80%):

δ = 2.18 normalpg normalm L^{- 1}

d = \frac{μ_{2} - μ_{1}}{σ \sqrt{2}} = \frac{1.47}{3.07} = 0.47

n = \frac{{([], ((), z_{1 - α / 2}) + ((), z_{1 - β}))}^{2}}{d^{2}} = \frac{{((), 1.96 + 0.84)}^{2}}{{((), 0.47)}^{2}} = 36

…”

Section: Experimental Statementioning

confidence: 99%

“…A sample size of at least 36 in each group was calculated according to the standard deviation of high-sensitivity (hs)-CRP in a similar study 30 in the following order ( = 0.05; power = 80%):…”

Section: Study Design and Subjectsmentioning

confidence: 99%

“…Various studies suggest that cardamom extracts display antimicrobial, anti‐cancer, anti‐inflammatory, anti‐proliferative, pro‐apoptotic and anti‐oxidative activities . Several animal and cellular model studies have shown anti‐inflammatory and anti‐oxidative activities of cardamom . A few human studies have been conducted to investigate the effects of cardamom on inflammation and oxidative stress status, which have shown conflicting results .…”

Section: Introductionmentioning

confidence: 99%

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