Improvement in the identification and quantification of UV filters and additives in sunscreen cosmetic creams by gas chromatography/mass spectrometry through three-way calibration techniques

Rubio, Laura; Valverde-Som, Lucía; Sarabia, L.A.; Ortiz, M.C.

doi:10.1016/j.talanta.2019.120156

Cited by 16 publications

(4 citation statements)

References 52 publications

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“…In recent years, some detection technologies of BP-type UVFs have been established, including gas chromatography (GC), 6 gas chromatography-mass spectrometry (GC-MS), 7 liquid chromatography (LC), 8 liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) 9 and luminescence sensing. 10 Among them, the luminescence sensing method provides much more competitive chances because of its simple operability, high sensitivity and selectivity.…”

Section: Introductionmentioning

confidence: 99%

Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Zhang

Ding

et al. 2023

Dalton Trans.

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Section: Introductionmentioning

confidence: 99%

Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Zhang

Ding

et al. 2023

Dalton Trans.

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“…Liquid products (eau de toilettes and perfumes) are directly injected, without sample preparation, except dilution using different solvents or filtration [ 107 , 108 , 109 ] (if the amount of nonvolatile constituents is low when submitted to GC, as the performance of the GC system is rarely hampered by other constituents of the sample). If the analytes occur in more complex media, such as creams, lotions, foundations, and lipsticks, they need to be extracted from their matrix, prior to their analysis, via different established methods: by a fluid (in one step extraction technique [ 110 , 111 , 112 , 113 ] and improved variants such as MSPD: matrix solid-phase dispersion [ 23 , 93 , 114 , 115 ], QuEChERS (quick, easy, cheap, effective, rugged, and safe extraction) [ 116 , 117 , 118 , 119 ], or energy-assisted extraction techniques: vortex-assisted extraction (VAE) [ 120 , 121 ], ultrasound-assisted extraction (UAE) [ 121 , 122 ], and pressurized liquid extraction (PLE) [ 121 , 123 ], by liquid–liquid extraction (LLE) techniques [ 120 , 124 , 125 , 126 , 127 , 128 ], by solid-phase extraction techniques (μSPE: micro solid-phase extraction, dSPE: dispersive solid-phase extraction; SBSE: stir bar sorptive extraction) [ 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 ], and gas-phase extraction (headspace solid-phase microextraction (HS-SPME) [ 139 ,…”

Section: Ms Analysis Of Cosmetic Ingredientsmentioning

confidence: 99%

Mass-Spectrometry-Based Research of Cosmetic Ingredients

Serb,

Georgescu,

Onulov

et al. 2024

Molecules

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Cosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often challenging because of their huge complexity and their adulteration. Among various analytical tools, mass spectrometry (MS) has been largely used for compound detection, ingredient screening, quality control, detection of product authenticity, and health risk evaluation. This work is focused on the MS applications in detecting and quantification of some common cosmetic ingredients, i.e., preservatives, dyes, heavy metals, allergens, and bioconjugates in various matrices (leave-on or rinse-off cosmetic products). As a global view, MS-based analysis of bioconjugates is a narrow field, and LC- and GC/GC×GC-MS are widely used for the investigation of preservatives, dyes, and fragrances, while inductively coupled plasma (ICP)-MS is ideal for comprehensive analysis of heavy metals. Ambient ionization approaches and advanced separation methods (i.e., convergence chromatography (UPC2)) coupled to MS have been proven to be an excellent choice for the analysis of scented allergens. At the same time, the current paper explores the challenges of MS-based analysis for cosmetic safety studies.

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“…Techniques such as flame atomic absorption spectroscopy and inductively coupled plasma atomic emission spectroscopy are used for the analysis of inorganic UV filters [15]. The detection of organic UV filters has included the use of UV-Vis spectroscopy [16], nuclear magnetic resonance spectroscopy [17], Raman spectroscopy [18], gas chromatography [19], and most commonly high-performance liquid chromatography (HPLC) [5,20]. In particular, reversedphase HPLC is the most frequently used method due to the simplicity of operation [21].…”

Section: Introductionmentioning

confidence: 99%

A simple and reliable isocratic high‐performance chromatographic assay for the simultaneous determination of hydrophilic benzophenone‐4 and lipophilic octocrylene in sunscreens

Pan

Svirskis

Waterhouse

et al. 2023

Intern J of Cosmetic Sci

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Objective This work aimed to develop a simple HPLC method for the simultaneous quantitative determination of the ultraviolet (UV) filters, hydrophilic benzophenone‐4 and lipophilic octocrylene, in the presence of three other commonly used UV filters, avobenzone, octisalate and homosalate. Methods Reverse‐phased HPLC was performed on a C18 column. A scouting gradient was initially used to determine the approximate mobile phase composition required for efficient analyte elution and separation before further optimization. The assay was validated with regard to specificity, linearity, intra‐ and inter‐day accuracy and precision, limits of detection and limits of quantification. An ultrasound dispersion extraction method for the UV filters from a commercial sunscreen was developed, and the extraction efficiencies from spiked samples were calculated. Results An acetonitrile‐methanol‐water mixture (20:67:13, v/v/v), where the water component contained 0.2% trifluoroacetic acid (v/v), was found to be the optimal mobile phase at a flow rate of 1.0 mL/min. The assay was linear between 1.0–100 μg/mL for both benzophenone‐4 and octocrylene (both correlation coefficients were above 0.999). There was no interference from the excipients of the sunscreen nor from the three other UV filters. The intra‐ and inter‐day accuracy was between 90.0–104.6% for both analytes. Extraction recoveries from a spiked commercial sunscreen were between 95.4 ± 2.1% to 98.5 ± 2.1% for benzophenone‐4, and between 87.3 ± 2.3% and 98.9 ± 3.1% for octocrylene. All validation parameters were within the acceptance criteria set out in the International Council for Harmonization (ICH) guidelines. The HPLC assay showed the extracted quantities of benzophenone‐4 and octocrylene from the commercial sunscreen closely matched claimed quantities. Conclusion The developed isocratic HPLC method was suitable for simultaneously determining the hydrophilic benzophenone‐4 and lipophilic octocrylene in the presence of other commonly used UV filters. Additionally, the extraction method was simple and effective for accurately quantifying the UV filters in a commercial sunscreen.

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Improvement in the identification and quantification of UV filters and additives in sunscreen cosmetic creams by gas chromatography/mass spectrometry through three-way calibration techniques

Cited by 16 publications

References 52 publications

Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Mass-Spectrometry-Based Research of Cosmetic Ingredients

A simple and reliable isocratic high‐performance chromatographic assay for the simultaneous determination of hydrophilic benzophenone‐4 and lipophilic octocrylene in sunscreens

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Improvement in the identification and quantification of UV filters and additives in sunscreen cosmetic creams by gas chromatography/mass spectrometry through three-way calibration techniques

Cited by 16 publications

References 52 publications

Post-synthetic functionalization of Zn-CP by Tb3+ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Post-synthetic functionalization of Zn-CP by Tb3+ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Mass-Spectrometry-Based Research of Cosmetic Ingredients

A simple and reliable isocratic high‐performance chromatographic assay for the simultaneous determination of hydrophilic benzophenone‐4 and lipophilic octocrylene in sunscreens

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Product

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Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone

Post-synthetic functionalization of Zn-CP by Tb³⁺ ions: a ratiometric luminescent sensor for the ultraviolet filter benzophenone