Improvement in antimicrobial properties of titanium by diethyl phosphite plasma-based surface modification

Can, Gizem Kaleli; Özgüzar, Hatice Ferda; Kahriman, Selahattin; Türkal, Miranda; Göçmen, Jülide Sedef; Yurtçu, Erkan; Mutlu, Mehmet

doi:10.1016/j.mtcomm.2020.101565

Cited by 10 publications

(7 citation statements)

References 41 publications

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“…Kaleli-Can et al used the plasma polymerization technique for surface modication with titanium using diethyl phosphite (DEP) as the gas source in an RF/lowpressure plasma device under 0.15 mbar. 102 The water contact angle of the DSP-coated Ti is signicantly smaller, and the surface energy is about two times higher than that of the unmodied Ti surface. The surface roughness was increased, and it had an inhibitory effect on C. albicans, which showed good antibacterial activity.…”

Section: Plasma Strategies In Surface Modification Processesmentioning

confidence: 98%

Surface modifications of biomaterials in different applied fields

Wang

2023

RSC Adv.

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Section: Plasma Strategies In Surface Modification Processesmentioning

confidence: 98%

Surface modifications of biomaterials in different applied fields

Wang

2023

RSC Adv.

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“…Due to the wide use of titanium and its alloys in implant dentistry, surfaces coated or modified with inherent bactericidal agents are being continuously investigated to prevent or treat peri-implantitis. These bactericidal agents include totarol, zinc, copper, silver, peptides, graphene oxide, and polymeric coatings on titanium and its alloys. − Some of the other generic antibacterial strategies, not limited to titanium-based implants, are discussed in a recent review . The strategies have been classified as antifouling, release-killing, contact killing and intrinsic antibacterial activity of implant materials.…”

Section: Strategies To Reduce Bacterial Colonization On Titanium and ...mentioning

confidence: 99%

Preventing Peri-implantitis: The Quest for a Next Generation of Titanium Dental Implants

Hasan

Bright

Hayles

et al. 2022

ACS Biomater. Sci. Eng.

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Titanium and its alloys are frequently the biomaterial of choice for dental implant applications. Although titanium dental implants have been utilized for decades, there are yet unresolved issues pertaining to implant failure. Dental implant failure can arise either through wear and fatigue of the implant itself or peri-implant disease and subsequent host inflammation. In the present report, we provide a comprehensive review of titanium and its alloys in the context of dental implant material, and how surface properties influence the rate of bacterial colonization and peri-implant disease. Details are provided on the various periodontal pathogens implicated in peri-implantitis, their adhesive behavior, and how this relationship is governed by the implant surface properties. Issues of osteointegration and immunomodulation are also discussed in relation to titanium dental implants. Some impediments in the commercial translation for a novel titanium-based dental implant from “bench to bedside” are discussed. Numerous in vitro studies on novel materials, processing techniques, and methodologies performed on dental implants have been highlighted. The present report review that comprehensively compares the in vitro, in vivo, and clinical studies of titanium and its alloys for dental implants.

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“…Plasma-polymerized diethyl phosphite (DEP) coated titanium (pp(DEP)-Ti) substrates exhibited excellent cytocompatibility and anti-biofilm properties. The painted surfaces were found to be hydrophobic, and the in vitro studies showed the antibacterial and anticandidal nature of the coating against Staphylococcus aureus and Candida albicans cells, proving to have a promising potential in treating peri-implantitis [ 104 ]. A highly efficient anti-bacterial coating comprising phosphonate/active ester block copolymers (pDEMMP-b-pNHSMA) with identical phosphonate segments was reported.…”

Section: Antibacterial Coatings On Titanium Implantsmentioning

confidence: 99%

Antibacterial Coatings for Titanium Implants: Recent Trends and Future Perspectives

et al. 2022

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Titanium and its alloys are widely used as implant materials for biomedical devices owing to their high mechanical strength, biocompatibility, and corrosion resistance. However, there is a significant rise in implant-associated infections (IAIs) leading to revision surgeries, which are more complicated than the original replacement surgery. To reduce the risk of infections, numerous antibacterial agents, e.g., bioactive compounds, metal ions, nanoparticles, antimicrobial peptides, polymers, etc., have been incorporated on the surface of the titanium implant. Various coating methods and surface modification techniques, e.g., micro-arc oxidation (MAO), layer-by-layer (LbL) assembly, plasma electrolytic oxidation (PEO), anodization, magnetron sputtering, and spin coating, are exploited in the race to create a biocompatible, antibacterial titanium implant surface that can simultaneously promote tissue integration around the implant. The nature and surface morphology of implant coatings play an important role in bacterial inhibition and drug delivery. Surface modification of titanium implants with nanostructured materials, such as titanium nanotubes, enhances bone regeneration. Antimicrobial peptides loaded with antibiotics help to achieve sustained drug release and reduce the risk of antibiotic resistance. Additive manufacturing of patient-specific porous titanium implants will have a clear future direction in the development of antimicrobial titanium implants. In this review, a brief overview of the different types of coatings that are used to prevent implant-associated infections and the applications of 3D printing in the development of antibacterial titanium implants is presented.

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Improvement in antimicrobial properties of titanium by diethyl phosphite plasma-based surface modification

Cited by 10 publications

References 41 publications

Surface modifications of biomaterials in different applied fields

Surface modifications of biomaterials in different applied fields

Preventing Peri-implantitis: The Quest for a Next Generation of Titanium Dental Implants

Antibacterial Coatings for Titanium Implants: Recent Trends and Future Perspectives

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