Abstract:The purpose of the study was to investigate self-nanoemulsifying drug delivery system (SNEDDS) as potential delivery system for poorly water soluble drug Lurasidone (LUR). SNEDDS was formulated using oil (Anise oil) surfactant (Tween ® 80), and co-surfactant (Polyethyleneglycol-600). Z-average size, PDI and in-vitro drug release were considered to screen and optimize the composition of liquid-SNEDDS. Following emulsification, the optimized formulation was selected to have the smallest mean particle size and hi… Show more
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