Improved Colorimetric Determination of Primary Aromatic Amines with 9-Chloroacridine: Application to Some Local Anesthetics

Determination of Sulfonamides and Local Anesthetics with 9-Chloroacridine by Quenching Fluorometry

“…Previous reports from this laboratory showed the reaction to be applicable to colorimetric determinations of sulfonamides and local anesthetics as well as most primary aromatic amines (5)(6)(7). It was observed that the formation of these derivatives resulted in a quenching of the fluorescence of the 9-chloroacridine reagent solution.…”