Improved adenoma detection with linked color imaging technology compared to white-light colonoscopy

Lovász, Barbara D.; Szalai, M; Oczella, L; Finta, Ádám; Dubravcsik, Zsolt; Madácsy, L

doi:10.1080/00365521.2020.1786850

Cited by 9 publications

(10 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9,26 Reports on ADR improvements were inconsistent, showing both significant and non-significant improvements in LCI compared with WLI. [25][26][27][28][29][30] TXI has a bright image similar to that of LCI, which is more suitable for lesion detection than NBI. In our study population, TXI had a higher ADR than WLI did.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Detection of colorectal adenomas with texture and color enhancement imaging: Multicenter observational study

Sakamoto

Ikematsu

Tamai

et al. 2022

Digestive Endoscopy

View full text Add to dashboard Cite

Objectives We aimed to evaluate the efficacy of texture and color enhancement imaging (TXI), which allows the acquisition of brighter images with enhanced color and surface structure in colorectal polyp detection compared to white light imaging. Methods Patients who underwent colonoscopy with repeated ascending colon observation using TXI and white light imaging between August 2020 and January 2021 were identified in three institutions. The outcomes included the mean number of adenomas detected per procedure (MAP), adenoma detection rate (ADR), and ascending colonic adenoma miss rate (Ac‐AMR). Logistic regression was used to determine the effects of the variables on the outcomes. Results We included 1043 lesions from 470 patients in the analysis. The MAP, ADR, flat polyp detection rate, and Ac‐AMR in TXI and white light imaging were 1.5% (95% confidence interval 1.3–1.6%) vs. 1.0% (0.9–1.1%), 58.2% (51.7–64.6%) vs. 46.8% (40.2–53.4%), 66.2% (59.8–72.2%) vs. 49.8% (43.2–56.4%), and 17.9% (12.1–25.2%) vs. 28.2% (20.0–37.6%), respectively. TXI, age, withdrawal time, and endoscopy type were identified as significant factors affecting the MAP and the ADR using multivariate regression analysis. Conclusions Our study indicates that TXI improve the detection of colorectal neoplastic lesions. However, prospective randomized trials are required to confirm these findings.

show abstract

Section: Discussionmentioning

confidence: 99%

“…In early trials, LCI was reported to be superior to WLI for polyp detection 9,26 . Reports on ADR improvements were inconsistent, showing both significant and non‐significant improvements in LCI compared with WLI 25–30 . TXI has a bright image similar to that of LCI, which is more suitable for lesion detection than NBI.…”

Section: Discussionmentioning

confidence: 99%

Detection of colorectal adenomas with texture and color enhancement imaging: Multicenter observational study

Sakamoto

Ikematsu

Tamai

et al. 2022

Digestive Endoscopy

View full text Add to dashboard Cite

show abstract

“…We excluded one study because that was not RCT [20]. Therefore, 10 RCTs with 5,510 patients were included in the meta-analysis [7][8][9][10][12][13][14][15][16][17] (Fig. 1).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Aside individual studies, a recent meta-analysis [11] including 6 RCTs and 1 parallel study concluded that LCI has J Gastrointestin Liver Dis, ePub ahead of printing significantly greater polyp detection rate (PDR) and ADR of previously missed polyps compared with WLI. After that, six RCTs comparing LCI and WLI have recently been published [12][13][14][15][16][17]. Therefore, we conducted a meta-analysis of published data in order to evaluate the efficacy of LCI.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Linked Color Imaging for Adenoma Detection. A Meta-analysis of Randomized Controlled Studies

Wang

et al. 2022

JGLD

View full text Add to dashboard Cite

Background and Aims: The effect of linked color imaging (LCI) compared with white light imaging (WLI) is conflicting. The aim of this meta-analysis is to compare the efficacy of LCI versus WLI for the adenoma detection. Methods: PubMed, Embase, Google Scholar and Cochrane Library were searched up to the end of Aug 18, 2021. All randomized controlled trials (RCTs) comparing LCI with WLI were included. Dichotomous data were pooled to obtain the relative risk (RR) with a 95% confidence interval (CI), whereas continuous data were pooled using a mean difference (MD) with 95%CI. Results: A total of 10 RCTs involving 5,510 patients were included. The use of LCI was associated with a statistically significant improvement in adenoma detection rate (ADR), polyp detection rate (PDR), mean adenomas per patient (MAP) and mean polyp per patient (MPP) when compared to WLI (ADR: RR=1.15, 95%CI: 1.07-1.23, p=0.0001, PDR: RR=1.15, 95%CI: 1.08-1.22, p<0.0001; MAP: MD=0.18, 95%CI: 0.09- 0.28, p=0.0002; MPP: MD=0.13, 95%CI: 0.01, 0.25, p=0.03). When stratified by size, LCI group had a higher detection rate of small adenomas (<10 mm) than the WLI group. Besides, LCI showed a significant decrease in adenoma miss rate (AMR) when compared to WLI. There were no statistically significant differences between the two groups in advanced ADR (AADR), sessile serrated lesion detection rate (SDR), cecal intubation rate, insertion time, and withdrawal time. Conclusions: The pooled evidence suggests that LCI can significantly improve the detection of ADR, especially for small adenomas (<10 mm). Moreover, the AMR were significantly lower using LCI compared with WLI.

show abstract

“…The most recent literature shows that techniques using electronic chromoendoscopy (EC), particularly from the latest generation, improve adenoma detection rates by enhancing the contrast between the lesion and the surrounding mucosa 1 2 3 4 . But these techniques, if they are simple to implement, are not widely used, especially in Europe, and there are no recommendations that impose these techniques first-line for those at average-risk of colorectal cancer (CRC).…”

Section: Challenges Regarding Detectionmentioning

confidence: 99%

Advanced diagnostic endoscopy for colorectal tumors: Challenges that need to be solved in the years to come

Ponchon

Hassan

2021

Endosc Int Open

View full text Add to dashboard Cite

Improved adenoma detection with linked color imaging technology compared to white-light colonoscopy

Cited by 9 publications

References 9 publications

Detection of colorectal adenomas with texture and color enhancement imaging: Multicenter observational study

Detection of colorectal adenomas with texture and color enhancement imaging: Multicenter observational study

The Effect of Linked Color Imaging for Adenoma Detection. A Meta-analysis of Randomized Controlled Studies

Advanced diagnostic endoscopy for colorectal tumors: Challenges that need to be solved in the years to come

Contact Info

Product

Resources

About