Imported Cases of Measles in Niigata, Japan in 2011

Watanabe, Kanako; Watanabe, K.; Tazawa, Takashi; Kon, Miyako; Tamura, Tsutomu; Komase, Katsuhiro

doi:10.7883/yoken.65.268

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This effort to detect MV by PCR and genotyping has continued during the elimination era in Japan. The molecular epidemiological data of MV in certain prefectures or cities were reported in previous studies (Aoki et al, 2009; Kurata et al, 2009; Nagano et al, 2011; Tanaka et al, 2011; Watanabe et al, 2012; Miyoshi et al, 2014, 2015, 2017; Nadaoka et al, 2014; Minagawa et al, 2015; Yagi et al, 2015; Kaida et al, 2018; Komabayashi et al, 2018), but a nationwide analysis was conducted in this study for the first time. The data demonstrated that many different MV strains were detected in Japan.…”

Section: Resultsmentioning

confidence: 60%

“…The MV genotyping data also suggested that between 2010 and 2012, Japan has experienced many imported measles cases from European countries. Importation of the genotype D4 strain from New Zealand was also detected in 2011 (Watanabe et al, 2012). The transmission of genotype D4 strains was completely interrupted after 2013 in Japan (Table 1).…”

Section: Resultsmentioning

confidence: 96%

“…D9 virus was also exported from the Philippines to Taiwan and Australia in 2010 and 2011, respectively (Jayamaha et al, 2012; Cheng et al, 2013). In Japan, importation of D9 strains from other Asian countries, such as Malaysia (National Institute of Infetious Diseases [NIID], and Tuberculosis, and Infectious Disease Control Division, Ministry of Health, Labor, and Welfare [MHLW], 2012a,b; Watanabe et al, 2012), Indonesia (National Institute of Infetious Diseases [NIID], and Tuberculosis, and Infectious Disease Control Division, Ministry of Health, Labor, and Welfare [MHLW], 2012a,b), and Thailand (National Institute of Infetious Diseases [NIID], and Tuberculosis, and Infectious Disease Control Division, Ministry of Health, Labor, and Welfare [MHLW], 2012a,b), were also detected in 2011. In 2011, as observed in Japan, genotype D9 strains were also predominant strains in Taiwan, Singapore, and New South Wales (Rosewell et al, 2012; Cheng et al, 2013; Ho et al, 2014), where endemic transmission of MV has been eliminated or well controlled.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Nationwide Molecular Epidemiology of Measles Virus in Japan Between 2008 and 2017

et al. 2019

Self Cite

View full text Add to dashboard Cite

Genotyping evidence that supports the interruption of endemic measles virus (MV) transmission is one of the essential criteria to be verified in achieving measles elimination. In Japan since 2014, MV genotype analyses have been performed for most of the measles cases in prefectural public health institutes nationwide. With this strong molecular epidemiological data, Japan was verified to have eliminated measles in March, 2015. However, even in the postelimination era, sporadic cases and small outbreaks of measles have been detected repeatedly in Japan. This study investigated the nationwide molecular epidemiology of MV between 2008 and 2017. The 891 strains in the total period between 2008 and 2017 belonged to seven genotypes (D5, D4, D9, H1, G3, B3, and D8) and 124 different MV sequence variants, based on the 450-nucleotide sequence region of the N gene (N450). The 311 MV strains in the postelimination era between 2015 and 2017 were classified into 1, 7, 8, and 32 different N450 sequence variants in D9, H1, B3, and D8 genotypes, respectively. Analysis of the detection period of the individual N450 sequence variants showed that the majority of MV strains were detected only for a short period. However, MV strains, MVs/Osaka.JPN/29.15/ [D8] and MVi/Hulu Langat.MYS/26.11/ [D8], which are named strains designated by World Health Organization (WHO), have been detected in many cases over 2 or 3 years between 2015 and 2017. The WHO-named strains have circulated worldwide, causing outbreaks in many countries. Epidemiological investigation revealed repeated importation of these WHO-named strains into Japan. To demonstrate the elimination status (interruption of endemic transmission) in situations with repeated importation of the same strains is challenging. Nevertheless, the detailed sequence analysis of individual MV strains and chronological analysis of these strains provided sufficient evidence to show that Japan has still maintained its measles elimination status in 2017.

show abstract