Importance of Virulence Factors in Bacterial Pathogenicity: A Review

Abstract

Understanding the strategies of bacterial infections requires an extensive knowledge of the essential role virulence factors play in bacterial pathogenicity. These components are essential in spreading of the infection, the capacity of the bacteria to avoid host defenses and the start of disease. The absence or presence of certain virulence factors has significant influence on the rate of infection dissemination. Virulence factors are divided into four groups: adhesion factors, invasion factors, toxin factors and immune evasion factors. The review here, addresses how virulence parameters affect host cells and tissues, how they may influence disease development and how they may be utilized to identify and treat bacterial infections. Controlling virulence parameters is also an important aspect of this. Virulence parameters expression can be influenced by variety of genetic and environmental variables, including quorum sensing which is not always present. Finally developing efficient prevention and therapeutic techniques for bacterial infections requires detailed understanding of the control of virulence parameters. Indicating the important role of virulence factors in bacterial pathogenicity is vital in the development of powerful treatment methods.