Importance of investigation of ovarian biopsy in assessing the ovarian reserve in infertile patients

An important problem in reproductology is inflammatory diseases of the pelvic organs. About 60% of patients with chronic salpingoophoritis are of reproductive age, and 65-77% of cases of acute processes turn into chronic. The analysis of the scientific literature on the effect of chronic salpingoophoritis on the reproductive function of women is carried out. The diagnostic significance of the ultrasound method in assessing the state of the ovarian reserve has been studied. The analysis of the dependence of the concentration of anti-Muller hormone and the indicators of the ovarian reserve was carried out. Evaluation of the ovarian reserve should be carried out using high-frequency transvaginal sensors. These methods allow us to study the architectonics of the intra-organ bloodstream of the ovaries. Modern ultrasound machines allow you to study in detail all the indicators of the ovarian reserve and remove Doppler parameters. Dopplerography can be considered effective for assessing blood flow in the ovaries. The PD energy doppler makes it possible to evaluate intra- and perifollicular blood flow in small diameter vessels. Extensive visualization capabilities are important, capable of creating a planar and 3D image of the ovary under study. An integrated approach is needed to assess the ovarian reserve. In comparison with ultrasound examination, the level of anti-muller hormone more fully shows the activity of immature follicles ranging in size from 0.2 to 4 mm, which are visible during ultrasound examination are poorly visible.

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Ovarian reserve in patients with borderline ovarian tumors after surgical treatment

Chugunova¹,

Pokul

2020

Medicinskij alfavit

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Borderline ovarian tumors are often diagnosed in women under the age of 40 years (31.8 %), which determines the need to optimize the management of this cohort of patients, taking into account the possibility of maintaining their reproductive function. Purpose of the study. Assessment of the ovarian reserve based on a comprehensive sonographic diagnosis of the ovarian reserve in patients of reproductive age with borderline ovarian tumors. Materials and methods. Group I (n = 103) included patients with borderline serous epithelial ovarian tumors. Group II (n = 95) was formed from women with mucinous epithelial ovarian tumors. Comparison group III (n = 189) included patients with benign ovarian cystadenomas. Ultrasound scanning of the pelvic organs and color Doppler mapping (DLC) were performed using Aloka 3500, Semiens G‑60 ultrasound scanners operating in real time and equipped with a pulsed doppler using a 3.5 MHz convex sensor and a 7.5 MHz transvaginal sensor. Results. The number of antral follicles does not depend on the volume of the ovary. The healthy remaining ovarian tissue of the ovary is most pronounced in groups I and III, significantly less represented in group II (p ≤ 0.0001). Three months after adnexectomy, ovulatory function in the intact (healthy) ovary was preserved in 71% (n = 49) of women from group I; in 89% (n = 73) of patients of group II and in 93% (n = 25) of respondents of group III, with a predominance in group II (φ* = 2.7; p ≤ 0.0010 and φ* = 1.6; p ≤ 0.0500). After a conservative operation, the function of the operated (resected) ovary detected ovulation in 62% (n = 21) of group I participants; 68% (n = 9) of women of group II and 86% (n = 139) of patients of group III. After 6 months, an increase in the number of antral ovaries and the number of ovulations with a predominance of ovarian reserve in group III (p ≤ 0.0010 and p ≤ 0.0001) was generally observed. Conclusions. Integrated ultrasound is a reliable and objective method that evaluates the features of the ovulatory reserve in patients with borderline and benign ovarian tumors, which makes it possible to formulate a prognosis of a woman’s reproductive health after various types of surgical treatment.

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Importance of investigation of ovarian biopsy in assessing the ovarian reserve in infertile patients

Cited by 3 publications

References 11 publications

Morphofunctional assessment of the ovarian follicular apparatus in patients with diminished ovarian reserve

Morphofunctional assessment of the ovarian follicular apparatus in patients with diminished ovarian reserve

Assessment of Ovarian Reserve in Patients With Chronic Salpingoophoritis

Ovarian reserve in patients with borderline ovarian tumors after surgical treatment

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