Implementing a negative-pressure isolation ward for a surge in airborne infectious patients

Miller, Shelly L.; Clements, Nicholas; Elliott, Steven A.; Subhash, Shobha S.; Eagan, Aaron; Radonovich, Lewis J.

doi:10.1016/j.ajic.2017.01.029

Cited by 53 publications

(64 citation statements)

References 20 publications

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“…Meanwhile, it is necessary to isolate patients with infectious diseases and suspected patients away from other patients to avoid nosocomial infection [25].…”

Section: Shenzhenmentioning

confidence: 99%

Analysis of epidemiological characteristics of coronavirus 2019 infection and preventive measures in Shenzhen China—a heavy population city

Yang

Wang

et al. 2020

Preprint

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Coronavirus 2019 infection (COVID-19) outbroke in Wuhan, Hubei and spread to all provinces in China and other countries. Shenzhen ranked the top cities outside Wuhan with reported 416 confirmed cases by February 20, 2020. Here, we analyzed the epidemiological characteristics of COVID-19 in Shenzhen and potential link to the preventive strategies for the whole city and inside hospitals. Based on the daily new cases, the epidemic of COVID-19 in Shenzhen can be classified into three phases: the slow increase phase from January 19 to January 28, the rapid increase and plateau phase from January 29 to February 5 and the decline phase since February 6. In the three phases, the number of patients from Hubei decreased, and the number of familial clustering cases increased. The newly diagnosed COVID-19 cases reached its peak around January 31, which was 7 days after the peak date of cases arrival at Shenzhen. A series of early preventive strategies were implemented since January 19, which included detection of body temperature at all entrances of main traffic and buildings, outpatients service specially for patients with fever in all main hospitals in Shenzhen. All the patients with fever were screened with nasal or throat swab PCR detection of coronavirus 2019, Chest CT and blood lymphocyte counting in order to find out early case of COVID-19. Observation wards were established in every main hospital and a designated hospital was responsible for admission and medical care of all confirmed cases. Protection procedure was established for all medical staff involved in the screening and care of suspected and confirmed cases. 14 days isolated observation of all subjects arrived at Shenzhen from Hubei was implemented in February 2. After the implementation of all these strategies and measures, the COVID-19 cases started to decline since February 6. There were almost no community transmission and nosocomial infection occurred in Shenzhen. In conclusion, in situation of major outbreak of respiratory infectious disease, such as COVID-19, in nearby province of Hubei, Shenzhen, a high population density, high proportion of external population and high mobility city, has to face the imported cases and risk of spreading the outbreak into Shenzhen city. The implementation of early preventive strategies and measures in Shenzhen were successful in early identification of COVID-19 cases and prevented major outbreak occurred in Shenzhen. Early identification of imported cases, prevention of family clustering transmission, preventive measures in the public area and very strict infection control procedure in hospital setting are crucial for the successful control of outbreak in Shenzhen.

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“…Meanwhile, it is necessary to isolate patients with infectious diseases and suspected patients away from other patients to avoid nosocomial infection [25].…”

Section: Shenzhenmentioning

confidence: 99%

Analysis of epidemiological characteristics of coronavirus 2019 infection and preventive measures in Shenzhen China—a heavy population city

Yang

Wang

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…One important suggestion is that people should receive flu shots, for in addition to protecting against influenza, vaccination would reduce the number of false positive 2019-nCoV cases reported since fewer people would have the common symptoms of both flu and coronavirus, and if a vaccinated person did get sick, it would raise the probability that the case is coronavirus as opposed to flu and make it more likely said person would seek care [13]. There are other practical aspects to explore, including the development of a less-precise but more rapid diagnostic mechanism, determining how long one can safely delay ill patients with symptoms from coming to the hospital to help alleviate congestion, and figuring out how quickly Airborne Infection Isolation Rooms (negative pressure units) can be created by hacking the ventilation system in ordinary wards to increase isolation capacity [14].…”

mentioning

confidence: 99%

Containing 2019-nCoV (Wuhan) coronavirus

Kaplan

2020

Health Care Manag Sci

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The novel coronavirus 2019-nCoV first appeared in December 2019 in Wuhan, China. While most of the initial cases were linked to the Huanan Seafood Wholesale Market, person-to-person transmission has been verified. Given that a vaccine cannot be developed and deployed for at least a year, preventing further transmission relies upon standard principles of containment, two of which are the isolation of known cases and the quarantine of persons believed at high risk of exposure. This note presents probability models for assessing the effectiveness of case isolation and quarantine within a community during the initial phase of an outbreak with illustrations based on early observations from Wuhan.Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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“…Negative pressure isolation room system (-9Pa) and HEPA15 filters were installed in COVID ICUs to contain airborne microorganisms within the room. Negative pressure isolation room is commonly used for COVID-19 positive patients with respiratory failure, usually treated with aerosol-generating C-PAP therapy (C-PAP beds) (6).…”

Section: World Count: 615mentioning

confidence: 99%

Management of healthcare areas for the prevention of COVID-19 emergency in an Italian teaching hospital in Pisa, Tuscany: A hospital renovation plan

Baggiani

Luchini

Giraldi

et al. 2020

Infect. Control Hosp. Epidemiol.

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Implementing a negative-pressure isolation ward for a surge in airborne infectious patients

Abstract: This study showed that establishing a temporary negative-pressure isolation ward is an effective method to increase surge capacity in a hospital.

Cited by 53 publications

References 20 publications

Analysis of epidemiological characteristics of coronavirus 2019 infection and preventive measures in Shenzhen China—a heavy population city

Analysis of epidemiological characteristics of coronavirus 2019 infection and preventive measures in Shenzhen China—a heavy population city

Containing 2019-nCoV (Wuhan) coronavirus

Management of healthcare areas for the prevention of COVID-19 emergency in an Italian teaching hospital in Pisa, Tuscany: A hospital renovation plan

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