Implementation of mature tea leaves extract in bioinspired synthesis of iron oxide nanoparticles: preparation, process optimization, characterization, and assessment of therapeutic potential

Probing the Molecular Assembly of a Metabolizer Drug with β-Cyclodextrin and Its Binding with CT-DNA in Augmenting Antibacterial Activity and Photostability by Physicochemical and Computational Methodologies

“…Our investigation confirmed that Gram-negative bacteria were more susceptible to the tested samples than the Gram-positive bacteria, which may be due to the presence of a thick peptidoglycan layer in Gram-positive bacterial cell making them more resistant as this layer protects the entry of desired chemical inside bacterial cell. 17 Borkowski et al, 65 in an antibacterial study on the application of theophylline-based ionic liquids, demonstrated that this chemical mainly creates cellular damage and deformed the bilayer, which ultimately leads to necrosis. The detailed mechanism of the dyphylline based inclusion complex includes the (a) absorption and penetration of the sample into the cell wall; (b) deactivation of membrane proteins and loss of regulation of metabolic processes; (c) distortion of the lipid bilayer and leakage of intracellular material; (d) formation of phospholipid micelles and further breakdown of the bilayer; and (e) cell lysis.…”

“…However, very limited information is available about the antibacterial effects of theophylline, and with regard to dyphylline, no report of bactericidal effects has been published to date as far as we know. Our investigation confirmed that Gram-negative bacteria were more susceptible to the tested samples than the Gram-positive bacteria, which may be due to the presence of a thick peptidoglycan layer in Gram-positive bacterial cell making them more resistant as this layer protects the entry of desired chemical inside bacterial cell . Borkowski et al, in an antibacterial study on the application of theophylline-based ionic liquids, demonstrated that this chemical mainly creates cellular damage and deformed the bilayer, which ultimately leads to necrosis.…”

“…The antimicrobial activity of the synthesized inclusion complex (IC) in comparison to the host (β-CD) and guest (dyphylline) was assessed against two Gram-negative and three Gram-positive bacterial strains following the disk diffusion method. 17 Gram-positive facultative anaerobic cocci Staphylococcus aureus ATCC 11,632 and aerobic or facultative endospore-forming Bacillus megaterium ATCC 14,581 and Bacillus subtilis ATCC 11,774, along with Gram-negative Escherichia coli ATCC 11,229 and Salmonella typhimurium ATCC 25,241, were chosen for the study. To get fresh and viable cells for the experiment, the studied microbes were grown in a nutrient broth for 6–8 h. From the nutrient broth, 200 μL of the actively growing test organism was added to the nutrient agar plate and, after uniform mixing, allowed to solidify.…”

“…The antimicrobial activity of the synthesized inclusion complex (IC) in comparison to the host (β-CD) and guest (dyphylline) was assessed against two Gram-negative and three Gram-positive bacterial strains following the disk diffusion method . Gram-positive facultative anaerobic cocci Staphylococcus aureus ATCC 11,632 and aerobic or facultative endospore-forming Bacillus megaterium ATCC 14,581 and Bacillus subtilis ATCC 11,774, along with Gram-negative Escherichia coli ATCC 11,229 and Salmonella typhimurium ATCC 25,241, were chosen for the study.…”

Green Synthesis and Antibacterial Activity of Ag/Fe2O3 Nanocomposite Using Buddleja lindleyana Extract

“…In recent years, leaf extract-mediated biosynthesis of nanomaterials has been extensively studied [ 1 , 2 , 3 , 4 ]. Leaf extract-mediated synthesis of nanomaterials is more eco-friendly and economical than other methods of synthesis such as chemical reduction and physical methods [ 5 , 6 , 7 ]. Due to the growing demand for ecologically friendly material synthesis techniques, the biosynthesis of nanomaterials has gained attention as an emerging feature of the interface of nanotechnology and biotechnology [ 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ].…”