Isoparametric B-spline wavelet functions can provide excellent approximation for smooth functions. In this paper, the response of composite laminated plate subjected to explosions is analyzed by using a double thick beam FEM mode based on the spline wavelet function. This mode, which can be considered in the distribution of normal stress and transverse shear stress simultaneously, is very important in the analysis of thick plate or blast-damage mechanism. The mode in analyzing underground structure and earth medium respond has the advantage of high precision and fast constringency and is easy to establish a element displacement function. The comparison between simulative and experimental results shows the effectiveness and precision of this method.