Implementation of a versatile research data acquisition system using a commercially available medical ultrasound scanner

Hemmsen, Martin Christian; Nikolov, Svetoslav Ivanov; Pedersen, Michael Ingemann; Pihl, Michael Johannes; Enevoldsen, Marie Sand; Hansen, Jens Munk; Jensen, Jørgen Arendt

doi:10.1109/tuffc.2012.2349

Cited by 41 publications

(20 citation statements)

References 30 publications

(21 reference statements)

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“…The ability to reconfigure the FPGA through software is useful when performing QD since a different set of reference signals and a low-pass filter are required for each transducer used. Due to the architecture of the FPGA, many algorithms can be parallelized; making it an ideal tool for many biomedical applications [23][24][25]. By utilizing the parallel nature of the FPGA, the time taken to perform QD can be greatly reduced.…”

Section: Introductionmentioning

confidence: 99%

Continuous real-time photoacoustic demodulation via field programmable gate array for dynamic imaging of zebrafish cardiac cycle

Mattison

Shelton

Maxson

et al. 2013

Biomed. Opt. Express

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A four dimensional data set of the cardiac cycle of a zebrafish embryo was acquired using postacquisition synchronization of real time photoacoustic b-scans. Utilizing an off-axis photoacoustic microscopy (OA-PAM) setup, we have expanded upon our previous work with OA-PAM to develop a system that can sustain 100 kHz line rates while demodulating the bipolar photoacoustic signal in real-time. Real-time processing was accomplished by quadrature demodulation on a Field Programmable Gate Array (FPGA) in line with the signal digitizer. Simulated data acquisition verified the system is capable of real-time processing up to a line rate of 1 MHz. Galvanometer-scanning of the excitation laser inside the focus of the ultrasonic transducer enables real data acquisition of a 200 by 200 by 200 pixel, volumetric data set across a 2 millimeter field of view at a rate of 2.5 Hz.

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Section: Introductionmentioning

confidence: 99%

Continuous real-time photoacoustic demodulation via field programmable gate array for dynamic imaging of zebrafish cardiac cycle

Mattison

Shelton

Maxson

et al. 2013

Biomed. Opt. Express

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“…One frame generated with SASB-THI followed one frame generated with DRF-THI. Images from the same anatomic location were thereby recorded almost simultaneously with both techniques, and ideal sequences for comparison were generated (Hemmsen et al 2010(Hemmsen et al , 2012c.…”

Section: Equipment and Data Acquisitionmentioning

confidence: 99%

Clinical Evaluation of Synthetic Aperture Harmonic Imaging for Scanning Focal Malignant Liver Lesions

Brandt

Hemmsen

Hansen

et al. 2015

Ultrasound in Medicine & Biology

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Abstract-The purpose of the study was to perform a clinical comparison of synthetic aperture sequential beamforming tissue harmonic imaging (SASB-THI) sequences with a conventional imaging technique, dynamic receive focusing with THI (DRF-THI). Both techniques used pulse inversion and were recorded interleaved using a commercial ultrasound system (UltraView 800, BK Medical, Herlev, Denmark). Thirty-one patients with malignant focal liver lesions (confirmed by biopsy or computed tomography/magnetic resonance) were scanned. Detection of malignant focal liver lesions and preference of image quality were evaluated blinded off-line by eight radiologists. In total, 2,032 evaluations of 127 image sequences were completed. The sensitivity (77% SASB-THI, 76% DRF-THI, p 5 0.54) and specificity (71% SASB-THI, 72% DRF-THI, p 5 0.67) of detection of liver lesions and the evaluation of image quality (p 5 0.63) did not differ between SASB-THI and DRF-THI. This study indicates the ability of SASB-THI in a true clinical setting.

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“…Spectral data were acquired using a convex array transducer connected to a 2202 ProFocus scanner (BK Medical, Herlev, Denmark) equipped with a UA2227 research interface [3]. Post-processing was performed in Matlab.…”

Section: A Acquisition Of Ultrasound Datamentioning

confidence: 99%

Ultrasound evaluation of an abdominal aortic fluid-structure interaction model

Traberg

Jensen

2014

2014 IEEE International Ultrasonics Symposium

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Abstract-Ultrasound measurements are used for evaluating biomechanics of the abdominal aorta (AA) predicted by a fluidstructure interaction (FSI) simulation model. FSI simulation models describe the complete arterial physiology by quantifying the mechanical response in the vessel wall caused by the percolating pulsating blood. But the predictability of FSI models needs validation for these to be usable for diagnostic purposes. Ultrasound measurements are suitable for such an evaluation as the wall displacement can be measured in vivo and compared to the wall displacement simulated in the FSI model. Spectral Doppler velocity data from 3 healthy male volunteers were used to construct inlet profiles for the FSI model. Simultaneously, wall movement was tracked and used for comparison to FSI model results. Ultrasound data were acquired using a scanner equipped with a research interface. The wall displacement was estimated by time shift estimation obtained from cross-correlation of signals to a fixed reference. The FSI model was constructed as a 2D axissymmetric pipe with lumen diameter predicted by B-mode images from each volunteer. Visual comparison of wall displacement over 1 cardiac cycle show agreement except for 1 volunteer (Male, 23 yrs.). The magnitude of the displacement in simulation, u fsi , and in vivo, u iv , is within the same order of magnitude for the young (u iv = 1.48 mm, u fsi = 1.12 mm) and middle-aged volunteer (u iv = 0.783 mm, u fsi = 1.31 mm). For the elderly volunteer the simulated displacement (u fsi = 0.975 · 10 −3 mm) is much smaller compared to in vivo (u iv = 0.979 mm). In conclusion, the FSI model predicts a much stiffer AA wall compared to measured displacements for the elderly volunteer. From the visual comparison in vivo wall motion is captured in the FSI model for 2 of the 3 volunteers.

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Implementation of a versatile research data acquisition system using a commercially available medical ultrasound scanner

Cited by 41 publications

References 30 publications

Continuous real-time photoacoustic demodulation via field programmable gate array for dynamic imaging of zebrafish cardiac cycle

Continuous real-time photoacoustic demodulation via field programmable gate array for dynamic imaging of zebrafish cardiac cycle

Clinical Evaluation of Synthetic Aperture Harmonic Imaging for Scanning Focal Malignant Liver Lesions

Ultrasound evaluation of an abdominal aortic fluid-structure interaction model

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