“…The critical analysis of the results (Table 2) showed that LEs ranged from 1 to 5, with 8 (29.6%) three meta-analyzes 18,25,32 , five systematic reviews of RCTs (SRRCT) 24,27,28,33,35 and 6 (22.2%) randomized clinical trials (RCT) 14,20,21,30,34,39 were found in LE 1 and 2 respectively; non-randomized controlled trials (NRCT) [15][16][17]22,23,26,29,31,[37][38]40 11 (40.7%) (LE 3); a Cohort 19 (3,7%) in LE 4; in LE 5 only one (3.7%) qualitative and quantitative descriptive study was identified 36 and none in the LE 6 and 7. Therefore, the studies focused on the hierarchical levels of evidence 1 to 3 12,13 considered high and moderate and when related to the quality of strong and sufficient evidence levels 13 , respectively, demonstrating that the PICS studied appear to be effective in pain control.…”