2007
DOI: 10.1532/hsf98.20070706
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Abstract: Patients who develop cardiogenic shock after acute myocardial infarction have a very high mortality rate despite early reperfusion therapy. Hemodynamic stabilization can often only be achieved by implanting a mechanical circulatory support system. When, in cases representing expansive myocardial impairment without any chance of recovery, pharmacological therapy and the use of percutaneous assist devices have failed, the implantation of a total artificial heart is indicated. We report our first experiences with… Show more

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Cited by 16 publications
(6 citation statements)
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References 30 publications
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“…A 2007 study at the University Hospital of the Ruhr‐University of Bochum showed that five patients with irreversible cardiogenic shock refractory to conventional drug therapy implanted with CardioWest TAH rapidly recovered from vital organ dysfunction. Four of the five patients received successful heart transplant (43). Initial experience with the AbioCor at the University of Louisville School of Medicine demonstrated that despite cases of mortality due to preexisting illness, seven patients ineligible for heart transplant exhibited proper TAH functioning with the AbioCor.…”
Section: Total Artificial Heartsmentioning
confidence: 99%
“…A 2007 study at the University Hospital of the Ruhr‐University of Bochum showed that five patients with irreversible cardiogenic shock refractory to conventional drug therapy implanted with CardioWest TAH rapidly recovered from vital organ dysfunction. Four of the five patients received successful heart transplant (43). Initial experience with the AbioCor at the University of Louisville School of Medicine demonstrated that despite cases of mortality due to preexisting illness, seven patients ineligible for heart transplant exhibited proper TAH functioning with the AbioCor.…”
Section: Total Artificial Heartsmentioning
confidence: 99%
“…All 13 patients implanted with the TAH survived to heart transplantation after a mean duration of 5.2 days 34 . Successful utilization of the TAH as a bridge to transplant in patients with AMI and cardiogenic has also been reported by Morshuis and colleagues 35 …”
Section: Mechanical Circulatory Supportmentioning
confidence: 62%
“…3,4 Further, Copeland et al demonstrated that risk factors after CardioWest TAH implantation as a bridge to transplantation in biventricular heart failure patients, including those with irreversible cardiac rejection, were a history of smoking and prolonged prothrombin time, without including chronic heart transplant rejection. 5 As an advantage, the cardiac output of the CardioWest TAH is generally 7-8 L/min, which not only improves pressure and flow to end organs, but also increases the "washing" of the device's surfaces that are in contact with blood, thus reducing the risk of thromboembolism.…”
Section: Discussionmentioning
confidence: 99%