2010
DOI: 10.1111/j.1525-1594.2010.00996.x
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: A growing population experiencing heart failure (100,000 patients/year), combined with a shortage of donor organs (less than 2200 hearts/year), has led to increased and expanded use of mechanical circulatory support (MCS) devices. MCS devices have successfully improved clinical outcomes, which are comparable with heart transplantation and result in better 1-year survival than optimal medical management therapies. The quality of perfusion provided during MCS therapy may play an important role in patient outcome… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

2
29
0
3

Year Published

2012
2012
2020
2020

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 47 publications
(34 citation statements)
references
References 46 publications
2
29
0
3
Order By: Relevance
“…This is a central issue, as frequency differences between induced and native pulse may cause sinusoidal interference, potentially leading to variations in pressure and flow (4). The novel controller and the novel diagonal pump continually autocorrect the response to minute changes in the patient's natural pulse on a beat-to-beat basis.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…This is a central issue, as frequency differences between induced and native pulse may cause sinusoidal interference, potentially leading to variations in pressure and flow (4). The novel controller and the novel diagonal pump continually autocorrect the response to minute changes in the patient's natural pulse on a beat-to-beat basis.…”
Section: Discussionmentioning
confidence: 99%
“…Theoretical considerations, animal experiments, and first experience in pediatric extracorporeal life support and cardiopulmonary bypass in adult cardiac surgery suggest that pulsatile flow may exert beneficial effects that could potentially relate to reduced systemic vascular resistance and protection of microcirculatory function, as well as improved catecholamine response, splanchnic perfusion, cerebral perfusion, and myocardial blood flow (4)(5)(6)(7). Theoretical considerations, animal experiments, and first experience in pediatric extracorporeal life support and cardiopulmonary bypass in adult cardiac surgery suggest that pulsatile flow may exert beneficial effects that could potentially relate to reduced systemic vascular resistance and protection of microcirculatory function, as well as improved catecholamine response, splanchnic perfusion, cerebral perfusion, and myocardial blood flow (4)(5)(6)(7).…”
mentioning
confidence: 99%
“…The authors suggest that more normal pulsatility of pressure and flow in the arterial system as a contributing factor. Indeed, potential consequences of the lack of arterial pulsatility with continuous flow devices has been debated for almost a decade (27, 28). An alternate hypothesis relates to the fact that, as noted above, pulsatile devices provide more unloading and result in greater degrees of reverse remodeling and continuous flow devices.…”
Section: Factors Associated With Recovery/remissionmentioning
confidence: 99%
“…Both the RotaFlow and CentriMag produce maximal RPMs in the 5,000-5,500 range although experimental models suggest that the RotaFlow may have better performance characteristics. 8 Other alternatives include the BioMedicus centrifugal pump and Abiomed BVS 5000 (Abiomed, Inc). The Abiomed BVS 5000 is an automated biventricular pneumatic pump that can be used for either LV or RV support.…”
Section: Commentmentioning
confidence: 99%