Impetigo herpetiformis during pregnancy: case report and review of the literature

Wolf, Yoram; Groutz, Asnat; Walman, Igal; Luxman, Dov; David, Menachem P.

doi:10.3109/00016349509008946

Cited by 20 publications

(12 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, the exact effects of gestational hypertension on morbidity and mortality have not been determined. The dermatological conditions in the cases described by Wolf et al [7] and in our patient worsened progressively, although there were no adverse perinatal outcomes after delivery. …”

Section: Discussionmentioning

confidence: 75%

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

et al. 2011

View full text Add to dashboard Cite

Background: Impetigo herpetiformis (IH) is a rare skin disorder that occurs during pregnancy. It was previously associated with high maternal and fetal mortality and morbidity, but now has a better prognosis. Case Report: We report a case of a pregnant woman with IH who presented with generalized erythematous pustular eruptions in the 32nd week of gestation. The IH progressed rapidly, and gestational hypertension was observed in the 36th week. The lesions did not subside, despite treatment with corticosteroids and phototherapy. She delivered a healthy male baby via cesarean section in the 37th week. One month after her delivery, her skin returned to normal, except for residual pigmentation, with complete recovery 3 months postpartum. Conclusion: An experienced medical team comprising obstetricians, dermatologists, perinatologists and neonatologists is critical to aggressively treat this life-threatening specific dermatosis of pregnancy and to prevent ensuing complications, such as fluid and electrolyte imbalance, secondary infection and placental insufficiency.

show abstract

Section: Discussionmentioning

confidence: 75%

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Es de muy rara ocurrencia, siendo excepcional la recurrencia [2][3][4] . Como en el caso clínico presentado, esta recurrencia se presenta comúnmente temprano y con mayor severidad.…”

Section: Discussionunclassified

“…Se han descrito cuadros de inicio tan precoz como desde el primer trimestre 3,5 . El curso de la enfermedad es invariablemente progresivo, regresando sólo después del parto con mínimas secuelas tardías 4 .…”

Section: Discussionunclassified

“…El diagnóstico diferencial debe realizarse con psoriasis pustulosa, dermatitis herpetiforme, eritema multiforme, pémfigus vulgaris, dermatosis pustular subcorneal y herpes gestationis 4,6,7 , considerándose como hallazgos claves en el diagnóstico de IH la presencia de pústulas dolorosas intraepidérmicas estériles, prurito moderado, compromiso sistémico y ausencia de antecedentes familiares 7 .…”

Section: Discussionunclassified

See 1 more Smart Citation

Impétigo herpetiforme recurrente: manejo exitoso con ciclosporina

Valdés

Núñez²,

Pedraza

et al. 2005

Rev. méd. Chile

View full text Add to dashboard Cite

esde que Hebra, en 1872, describió por primera vez esta enfermedad de rara ocurrencia 1 , el pronóstico feto-materno del impétigo herpetiforme (IH) ha presentado una gran mejoría, secundaria esencialmente al apoyo clínico multidisciplinario al binomio madre-hijo y a la corticoterapia. Cuando estas medidas son insuficientes para el control de la enfermedad se ha planteado la asociación terapéutica con ciclosporina.Se presenta un caso clínico de impétigo herpetiforme recidivado en un segundo embarazo y refractario al tratamiento de apoyo multisistémico y corticoidal, por lo que se decidió asociar terapia con ciclosporina, obteniéndose una buena respuesta clínica materna y un buen resultado perinatal. CASO CLÍNICOPaciente de 24 años, con antecedentes de psoriasis en control desde los 12 años; fórmula obstétri-Rev Méd

show abstract

“…1 It is potentially serious and aggressive treatment is usually required. 2 The eruption consists of urticarid erythema which begins in the flexures, especially in the inguinal region, with superficial pustules arranged in rings or groups at the margins of the lesion. The lesions spread gradually until the entire body is involved, except for the face, hands and feet.…”

Section: Discussionmentioning

confidence: 99%

Impetigo Herpetiformis: An Obstetric Concern

1998

View full text Add to dashboard Cite

Impetigo herpetiformis, a very rare form of pustular psoriasis occurring in pregnancy, is potentially serious and aggressive treatment is usually required. We report a case of a patient presenting with two consecutive pregnancies complicated by impetigo herpetiformis. The disease appeared much earlier than the classic third trimester presentation. The first pregnancy was induced because of worsening symptoms, while the second pregnancy ended in a stillbirth. Early diagnosis and treatment of impetigo herpetiformis is essential to reduce both maternal and fetal morbidity and mortality. Case ReportA 27-year-old Primigravida presented at 19 weeks' gestation, complaining of a papular skin eruption for the previous three months. This was diagnosed as psoriasis. The patient gave no family history of any skin conditions. At 36 weeks, she presented with a one-week history of malaise, fever, leg pains and worsening of the previously noted generalized skin eruption.On examination, large circinate lesions with superficial pustules at the periphery and central desquamation were noted, mostly on the legs. Some scattered papules, pustules and psoriatic lesions were seen on the elbow and abdomen. A clinical diagnosis of impetigo herpetiformis, also called generalized pustular psoriasis of pregnancy, was made and treatment was commenced with Eucerine cream and oral dosage of 40 mg prednisolone daily. Two biopsies taken from the lesion showed acanthosis, parakeratosis and intraepidermal pustules filled with numerous neutrophils. The immunofluorescence studies were negative for IgG, IgM, IgA, C 3 and fibrinogen. Blood studies showed a leukocytosis of 13.2x10 9 /L (normal range 5-10x10 9 /L) and mild hypocalcemia of 2 mmol/L (normal range 2.2-2.625 mmol/L). In spite of the treatment, the lesions got worse, and so labor was induced at 38 weeks, with the delivery of an infant weighing 3.020 kg, with Apgar scores of 6 and 8 at 1 and 5 minutes, respectively. Two days postpartum, the lesions began to improve and the patient was discharged home on 5-fluorouracil cream and clobetasol propionate ointment. When she was seen two weeks later, there was a marked improvement in her condition, although new pustular lesions were still appearing. The prednisolone therapy was re-commenced at 40 mg/day for one week, and the dose was gradually reduced over the next four weeks to 5 mg daily. There was some improvement, but since new lesions were still appearing, methotrexate 5 mg once/week orally was commenced and gradually increased to 20 mg weekly. Serial CBC and hepatic panel were performed weekly and vitamin D 50,000 IU daily and vitamin E were given as supplements for three months postpartum. The lesions resolved completely during this period, so methotrexate and prednisolone were gradually tapered off over the next three months.At six months postpartum, all lesions had cleared completely, except for some mild postinflammatory pigmentation. Immediately after discontinuing the treatment, the patient became pregnant again. She had a recurrence of t...

show abstract

Impetigo herpetiformis during pregnancy: case report and review of the literature

Cited by 20 publications

References 14 publications

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

Impétigo herpetiforme recurrente: manejo exitoso con ciclosporina

Impetigo Herpetiformis: An Obstetric Concern

Contact Info

Product

Resources

About