Proton pump inhibitors (PPIs) are medications that are frequently prescribed for gastroesophageal reflux disease. However, a few case reports have described neuropsychiatric symptoms following PPI use. In this report, we present a case of visual hallucinations secondary to PPI usage and propose possible mechanisms. In this case, a 65-year-old man with no psychiatric history developed acute visual hallucinations following initiation of omeprazole, in the absence of delusions, paranoia, and other psychotic symptoms. The visual hallucinations began after the patient started treatment with omeprazole and resolved almost immediately upon discontinuation of omeprazole. To treat symptoms of gastroesophageal reflux disease, omeprazole was replaced with famotidine, and the visual hallucinations did not recur after the omeprazole had been discontinued. No other psychotic signs or symptoms were present in this patient throughout the duration of his hospitalization. Although the scientific literature provides limited information on psychosis related to PPI use, a growing number of case reports and studies in recent years have suggested that neuropsychiatric symptoms may occur after PPI use. It is our hope that this case report adds to the scientific and medical knowledge in this area.
esde que Hebra, en 1872, describió por primera vez esta enfermedad de rara ocurrencia 1 , el pronóstico feto-materno del impétigo herpetiforme (IH) ha presentado una gran mejoría, secundaria esencialmente al apoyo clínico multidisciplinario al binomio madre-hijo y a la corticoterapia. Cuando estas medidas son insuficientes para el control de la enfermedad se ha planteado la asociación terapéutica con ciclosporina.Se presenta un caso clínico de impétigo herpetiforme recidivado en un segundo embarazo y refractario al tratamiento de apoyo multisistémico y corticoidal, por lo que se decidió asociar terapia con ciclosporina, obteniéndose una buena respuesta clínica materna y un buen resultado perinatal. CASO CLÍNICOPaciente de 24 años, con antecedentes de psoriasis en control desde los 12 años; fórmula obstétri-Rev Méd
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