Impairment in Guillain–Barré syndrome during the first 2 years after onset: a prospective study

Forsberg, Anette; Press, Rayomand; Einarsson, Ulrika; Pedro‐Cuesta, Jesús de; Holmqvist, Lotta Widén

doi:10.1016/j.jns.2004.09.021

Cited by 53 publications

(59 citation statements)

References 26 publications

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“…More than 80 % of GBS patients reported pain in the acute phase of the disease [25,26]. Forsberg et al [4] showed that 33 % of GBS patients suffered from pain 2 years after acute disease. In our study, nearly 70 % of GBS patients reported pain, and almost 25 % of the patients had pain in more than one limb.…”

Section: Discussionmentioning

confidence: 99%

“…The results are important, since the long-term outcome after GBS may be variable [3][4][5] poliomyelitis sequelae influences activities of daily living [5,10,23,24,37,38]. Clinical scales often do not reflect functional disability [39], and this study therefore used the DRI scale assessing 10 activities of daily living.…”

Section: Discussionmentioning

confidence: 99%

“…Pain can sometimes be severe, and autonomic dysfunction is common [1,2]. There are few studies regarding longterm outcome after GBS, and the results show that the recovery is not always complete and persistent impairment may occur [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…Comparing diseases may help to find common underlying mechanisms and better understand long-term health problems and complaints [14]. Both diseases may develop similar sequelae such as fatigue, pain and muscle weakness after the acute disease [4,8,13]. However, only few studies have focused on the relationships between these symptoms.…”

Section: Introductionmentioning

confidence: 99%

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Fatigue, pain and muscle weakness are frequent after Guillain-Barré syndrome and poliomyelitis

2009

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Fatigue, pain and muscle weakness are frequent after Guillain-Barré syndrome and poliomyelitis

2009

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“…The geographic distribution of pain is broad, and pain can occur as a sentinel symptom prior to weakness, along with the onset of weakness, and can continue for at least 2 years [6]. Fatigue may persist for decades after the weakness from GBS has resolved, indicating multimodal long-term impact in some patients [7].…”

Section: Introductionmentioning

confidence: 99%

Headache and Pain in Guillain-Barré Syndrome

Farmakidis

Inan

Milstein

et al. 2015

Curr Pain Headache Rep

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While moderate and severe back or extremity pain is frequent in Guillain-Barré syndrome (GBS), headache appears to be uncommon. Most of the reports of headache in GBS place it in the context of the posterior reversible encephalopathy syndrome (PRES) which is increasingly recognized as a likely dysautonomia-related GBS complication. There are also a few reports of headache in the setting of increased CSF pressure and papilledema and in association with the Miller Fisher GBS variant. In comparison, back and extremity pain is highly prevalent. Aching muscle pain and neuropathic pain are the two most common of several pain types. Pain may be a heralding feature and has been described in patients as long as 2 years after disease onset. Pain management is a major axis of treatment in GBS. Gabapentin is a reasonable first-line choice, and opioid medications can be added for more severe pain but there are few clinical trials to inform specific recommendations. While the understanding of pain pathophysiology in GBS is incomplete, its prevalence and clinical impact are increasingly recognized and studied. Pain should be considered a cardinal manifestation of GBS along with acute, mostly symmetric weakness and diminished reflexes.

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