Impaired recognition and experience of disgust following brain injury

Calder, Andrew J.; Keane, Jill; Manes, Facundo; Antoun, Nagui M.; Young, Andrew W.

doi:10.1038/80586

Cited by 694 publications

(454 citation statements)

References 11 publications

Supporting

Mentioning

404

Contrasting

Unclassified

Order By: Relevance

“…Our findings of the left anterior insula focus whose activity was related to the perceived unpleasantness, depending on each subject's susceptibility to the stimuli, is in line with electrophysiological (Krolak-Salmon et al, 2003), lesion (Calder et al, 2000), and brain mapping (Phillips et al, 1997;Schienle et al, 2002;Wicker et al, 2003;Wright et al, 2004) studies on the involvement of this region in feeling and recognizing disgust. The results of a meta-analysis on neuroimaging studies of emotion (Wager et al, 2003) also showed an above-chance density of withdrawal-related activation foci in the left (but not in the right) mid-insula.…”

Section: Brain Regions Involved In the Observation Of Unpleasant Stimulisupporting

confidence: 65%

“…In the neutral condition, the hand/foot was touched by a neutral stimulus (e.g., a ball or a pen); in the disgusting condition, it was touched by a disgusting stimulus (spider, beetle, earthworm, or grasshopper); in the painful condition the hand/foot was wounded by a knife or a syringe. Although the term "disgust" is etymologically related to aversive stimuli in the olfaction and taste domains, by extension it has become associated with other classes of stimuli causing strong dislike and repulsion, such as some animal species, deformed body parts, poor hygiene, and body products (Calder et al, 2000;Schienle et al, 2002). In the present study, we chose to present animals touching body parts to make the disgusting stimuli as similar as possible to the other two classes with respect to skin contact.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Does It Look Painful or Disgusting? Ask Your Parietal and Cingulate Cortex

Benuzzi¹,

Lui²,

Duzzi³

et al. 2008

J. Neurosci.

139

109

View full text Add to dashboard Cite

Looking at still images of body parts in situations that are likely to cause pain has been shown to be associated with activation in some brain areas involved in pain processing. Because pain involves both sensory components and negative affect, it is of interest to explore whether the visually evoked representations of pain and of other negative emotions overlap. By means of event-related functional magnetic resonance imaging, here we compare the brain areas recruited, in female volunteers, by the observation of painful, disgusting, or neutral stimuli delivered to one hand or foot. Several cortical foci were activated by the observation of both painful and disgusting video clips, including portions of the medial prefrontal cortex, anterior, mid-, and posterior cingulate cortex, left posterior insula, and right parietal operculum. Signal changes in perigenual cingulate and left anterior insula were linearly related to the perceived unpleasantness, when the individual differences in susceptibility to aversive stimuli were taken into account. Painful scenes selectively induced activation of left parietal foci, including the parietal operculum, the postcentral gyrus, and adjacent portions of the posterior parietal cortex. In contrast, brain foci specific for disgusting scenes were found in the posterior cingulate cortex. These data show both similarities and differences between the brain patterns of activity related to the observation of noxious or disgusting stimuli. Namely, the parietal cortex appears to be particularly involved in the recognition of noxious environmental stimuli, suggesting that areas involved in sensory aspects of pain are specifically triggered by observing noxious events.

show abstract

Section: Brain Regions Involved In the Observation Of Unpleasant Stimulisupporting

confidence: 65%

Section: Methodsmentioning

confidence: 99%

Does It Look Painful or Disgusting? Ask Your Parietal and Cingulate Cortex

Benuzzi¹,

Lui²,

Duzzi³

et al. 2008

J. Neurosci.

139

109

View full text Add to dashboard Cite

show abstract

“…So far, no brain mapping studies have assessed the recognition of disgust by individuals with autism spectrum conditions. However, studies of patients with insula and basal ganglia lesions report specific difficulties with the recognition and experience of disgust, suggesting brain specificity for this emotion (Calder, Keane, Manes, Antoun, & Young, 2000;Calder, Lawrence, & Young, 2001).…”

Section: Discussionmentioning

confidence: 99%

The Cambridge Mindreading (CAM) Face-Voice Battery: Testing Complex Emotion Recognition in Adults with and without Asperger Syndrome

Golan

Baron‐Cohen

Hill

2006

J Autism Dev Disord

263

195

View full text Add to dashboard Cite

Adults with Asperger Syndrome (AS) can recognise simple emotions and pass basic theory of mind tasks, but have difficulties recognising more complex emotions and mental states. This study describes a new battery of tasks, testing recognition of 20 complex emotions and mental states from faces and voices. The battery was given to males and females with AS and matched controls. Results showed the AS group performed worse than controls overall, on emotion recognition from faces and voices and on 12/20 specific emotions. Females recognised faces better than males regardless of diagnosis, and males with AS had more difficulties recognising emotions from faces than from voices. The implications of these results are discussed in relation to social functioning in AS.

show abstract

“…The interested reader should refer to authoritative overviews on this topic (e.g., Adolphs, 2002b;Phillips et al, 2003). To summarize the reported relationships: the amygdala has been associated with negative facial expressions and emotional prosody (Adolphs & Tranel, 2003, 2004Adolphs et al, 1995Adolphs et al, , 2001bCardinal et al, 2002;Critchley et al, 2000b;Morris et al, 1996Morris et al, , 2001Phillips et al, 2003;Scott et al, 1997;Stork & Pape, 2002;Yang et al, 2002); the anterior cingulate cortex with facial and prosodic expressions (Holland & Sonderman, 1974;Hornak et al, 2004;Streit et al, 1999); the anterior insula with both facial and prosodic expressions of disgust (Calder et al, 2000(Calder et al, , 2001(Calder et al, , 2003Phillips et al, 2003); the right somatosensory cortex (Adolphs et al, 1996 and the temporal visual cortex with facial expressions (Critchley et al, 2000b;Haxby et al, 2002;Streit et al, 1999;Weddell, 1994); the middle temporal gyrus with bimodal emotional expressions ; the right frontoparietal operculum, bilateral frontal pole, and middle right superior temporal sulcus with emotional prosody (Adolphs, 2002b;Grandjean et al, 2005;Pell, 2006); and the orbitofrontal and medial prefrontal cortices, which together comprise the ventromedial prefrontal region, with facial and prosodic expressions (Barrash et al, 2000;Blair et al, 1999;Cicerone & Tanenbaum, 1997;Damasio, 1994;G...…”

Section: Neuropsychological Bases Of Emotion Perception Deficits In Tbimentioning

confidence: 99%

Emotion perception deficits following traumatic brain injury: A review of the evidence and rationale for intervention

Bornhofen

McDonald

2008

J Int Neuropsychol Soc

156

105

View full text Add to dashboard Cite

While the cognitive disturbances that frequently follow severe traumatic brain injury (TBI) are relatively well understood, the ways in which these affect the psychosocial functioning of people with TBI are yet to be determined and have thus received little attention in treatment research. Growing evidence indicates that a significant proportion of individuals with TBI demonstrate an inability to recognize affective information from the face, voice, bodily movement, and posture. Because accurate interpretation of emotion in others is critical for the successful negotiation of social interactions, effective treatments are necessary. Until recently, however, there have been no rehabilitation efforts in this area. The present review examines the literature on emotion perception deficits in TBI and presents a theoretical rationale for targeted intervention. Several lines of research relevant to the remediation of emotion perception in people with TBI are considered. These include work on emotion perception remediation with other cognitively impaired populations, current neuropsychological models of emotion perception and underlying neural systems, and recent conceptualizations of remediation processes. The article concludes with a discussion of the importance of carrying out efforts to improve emotion perception within a contextualized framework in which the day-to-day relevance of training is clear to all recipients. (JINS, 2008, 14, 511-525.)

show abstract

Impaired recognition and experience of disgust following brain injury

Cited by 694 publications

References 11 publications

Does It Look Painful or Disgusting? Ask Your Parietal and Cingulate Cortex

Does It Look Painful or Disgusting? Ask Your Parietal and Cingulate Cortex

The Cambridge Mindreading (CAM) Face-Voice Battery: Testing Complex Emotion Recognition in Adults with and without Asperger Syndrome

Emotion perception deficits following traumatic brain injury: A review of the evidence and rationale for intervention

Contact Info

Product

Resources

About