Impaired cognitive functions in mild traumatic brain injury patients with normal and pathologic magnetic resonance imaging

Kurča, Egon; Sivák, Štefan; Kucera, P

doi:10.1007/s00234-006-0109-9

Cited by 108 publications

(49 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These impairments can compromise other abilities, such as attention and memory 13,14 . After the period of post-traumatic amnesia (PTA), patients who experienced severe TBI may present memory disorders of variable intensity 15 ; damages of short term and long term 7,[9][10][11]16,17 memory. Changes in behavior and personality may be associated to TBI, such as reduction in motivation and self-esteem, difficulty with empathy 7 , emotional processing, loss of insight, psychosocial difficulties 8 , post-traumatic stress disorder, depression, anxiety, and fatigue 5,7,8,12,18,19 .…”

mentioning

confidence: 99%

Cognitive deficits in patients with mild to moderate traumatic brain injury

Miotto

Cinalli

Serrão

et al. 2010

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Traumatic brain injury (TBI) is one of the most frequent causes of brain damage. Cognitive deficits reported in the literature after moderate to severe TBI include memory, language, executive functions, attention and information processing speed impairments. However, systematic studies on patients with mild TBI are scarce although neuropsychological changes are present. Objective: To investigate the cognitive functioning of patients with mild to moderate TBI. Method: We evaluated 12 patients with mild to moderate TBI using a comprehensive protocol (PN01) of neuropsychological tests. Results: There were significant deficits of episodic memory including immediate and delayed verbal memory recall, verbal recognition, immediate and delayed visual memory recall, naming, verbal fluency and information processing speed. Conclusion: These results emphasize the importance of comprehensive neuropsychological assessments even in cases of mild TBI in order to identify impaired and preserved functions providing adequate managing including rehabilitation programs for each case. Key words: traumatic brain injury, cognitive deficits, mild to moderate level.Alterações neuropsicológicas em pacientes com traumatismo crânio encefálico levemoderado RESUMO Traumatismo craniencefálico (TCE) é uma das causas mais freqüentes de lesão cerebral. São relatados na literatura déficits cognitivos após TCE moderado-grave relacionados à memória, linguagem, funções executivas, atenção e velocidade de processamento de informações. Estudos em pacientes com TCE leve são escassos embora alterações neuropsicológicas sejam encontradas nestes pacientes. Objetivo: Investigar o funcionamento cognitivo de pacientes com TCE leve e moderado através de um protocolo abrangente (PN01) de testes neuropsicológicos. Método: Foram avaliados 12 pacientes com TCE leve e moderado. Resultados: Foram identificados déficits graves de memória episódica verbal para evocação imediata, tardia e de reconhecimento, de memória episódica visuo-espacial para evocação imediata e tardia, nomeação, fluência verbal nominal e velocidade de processamento de informações. Conclusão: Os resultados do estudo argumentam a favor da importância de avaliação neuropsicológica abrangente mesmo em casos de TCE leve a fim de se identificar funções comprometidas e preservadas, proporcionando condutas e programas de reabilitação adequados a cada caso. Palavras-chave: traumatismo crânio encefálico, déficits cognitivos, grau leve e moderado.

show abstract

mentioning

confidence: 99%

Cognitive deficits in patients with mild to moderate traumatic brain injury

Miotto

Cinalli

Serrão

et al. 2010

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…Meta analyses suggest that these symptoms typically resolve within three months of the trauma (Frencham, Fox, & Mayberry, 2005;Larrabee et al, 1997;Schretlen & Shapiro, 2003), but a significant minority of mild TBI patients (7% to 33%) have residual deficits in the speed of processing information, memory, and attention (Bernstein, 2002;Bigler, 2008;Mathias, Beall, & Bigler, 2004). Individuals with complicated mild TBI fare worse and have deficits at 3 months and a year following TBI (Borgaro et al, 2003;Kashluba et al, 2008;Kurca et al, 2006) and have a higher risk of developing epilepsy , further complicating the clinical presentation.…”

Section: Classification Schemes Of Tbimentioning

confidence: 99%

Call for an Integrative and Multi-Disciplinary Approach to Traumatic Brain Injury (TBI)

Mansour¹,

Lajiness-O’Neill²

2015

PSYCH

View full text Add to dashboard Cite

Much has been gained in our understanding of the psychopathology, assessment, and treatment of TBI. Still lacking is the breadth and depth that an integrative and multi-disciplinary approach to TBI portends. While there is a greater awareness of a need for such a systems-based approach as evidenced by the number of professional organizations and government agencies recently advocating a need for standardization in the collection data in TBI, the application of multi-dimensional approach, and the development novel strategies to deliver prevention, assessment and treatment to large, diverse populations, we are still in the early stages in making this important shift. In the nearer term, there are clinical assessment and interventional programs that can be developed and empirically validated to bring us closer to this integrative, multi-disciplinary ideal. The following review calls for a universal diagnostic classification system for TBI, integration of pathophysiology and pharmacological and rehabilitative therapies, development of treatments addressing disorders comorbid with TBI, and the delivery of assessment and treatment services to large underserved populations.

show abstract

“…Nonetheless, up to 35% of individuals continue to have ongoing cognitive, emotional and somatic symptoms when re-assessed up to 6 months post-injury [12]. Cognitive deficits encompassing visual processing [13], learning, memory, selective attention and executive function [14] have been identified post-mTBI.…”

Section: Introductionmentioning

confidence: 99%