Impact of troponin 1 on long‐term mortality after emergency orthopaedic surgery in older patients

Chong, Carol P; Lam, Que; Ryan, Julie; Sinnappu, Rabindra N.; Lim, Wen Kwang

doi:10.1111/j.1445-5994.2009.02063.x

Cited by 13 publications

(9 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some studies reported an increase in short- and long-term mortality, [ 16 – 18 ] whereas other did not. [ 19 – 21 ] Moreover, these studies did not distinguish ITR and myocardial infarction according to its universal definition. [ 4 ] In these elderly patients with hip fracture, an ITR may occur more frequently because of events such as atrial fibrillation or transient supply/demand mismatch.…”

Section: Introductionmentioning

confidence: 99%

Isolated cardiac troponin rise does not modify the prognosis in elderly patients with hip fracture

et al. 2017

View full text Add to dashboard Cite

Perioperative myocardial infarction remains a life-threatening complication in noncardiac surgery and even an isolated troponin rise (ITR) is associated with significant mortality. Our aim was to assess the prognostic value of ITR in elderly patients with hip fracture.In this cohort study, all patients admitted between 2009 and 2013 in our dedicated geriatric postoperative unit after hip fracture surgery with a cardiac troponin I determination were included and divided into Control, ITR, and acute coronary syndrome (ACS) groups. The primary end point was a composite criteria defined as 6-month mortality and/or re-hospitalization. Secondary end points included 30-day mortality, 6-month mortality, and 6-month functional outcome.Three hundred twelve patients were (age 85 ± 7 years) divided into Control (n = 217), ITR (n = 50), and ACS (n = 45) groups. There was no significant difference for any postoperative complications between ITR and Control groups. In contrast, atrial fibrillation, acute heart failure, hemorrhage, and ICU admission were significantly more frequent in the ACS group. Compared to the Control group, 6-month mortality and/or rehospitalization was not significantly modified in the ITR group (26% vs. 28%, P = 0.84, 95% confidence interval [CI] of the difference -13%–14%), whereas it was increased in the ACS group (44% vs. 28%, P = 0.02, 95% CI of the difference 2%–32%). ITR was not associated with a higher risk of new institutionalization or impaired walking ability at 6 months, in contrast to ACS group.In elderly patients with hip fracture, ITR was not associated with a significant increase in death and/or rehospitalization within 6 months.

show abstract

Section: Introductionmentioning

confidence: 99%

Isolated cardiac troponin rise does not modify the prognosis in elderly patients with hip fracture

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Using less sensitive cardiac troponin assays, myocardial necrosis occurs in approximately 6% of patients undergoing major joint arthroplasty,24 and predicts worse long-term outcomes 25. Patients undergoing joint replacement surgery tend to be older.…”

Section: Discussionmentioning

confidence: 99%

Perioperative myocardial necrosis in patients at high cardiovascular risk undergoing elective non-cardiac surgery

Alcock

Kouzios

Naoum

et al. 2012

Heart

View full text Add to dashboard Cite

Objective Cardiovascular complications are important causes of morbidity and mortality in elective non-cardiac surgery. Although difficult to diagnose, perioperative myocardial infarction (MI) remains prognostically important. High-sensitivity troponin T (hs-TnT) assays allow detection of very minor damage to cardiac muscle. These assays are yet to be fully evaluated in the perioperative setting. Our aim was to determine the incidence and predictors of myocardial necrosis in patients at high cardiovascular risk undergoing elective non-cardiac surgery using hs-TnT.

show abstract

“…After emergency orthopaedic surgery, a high incidence of Tn I increases were noted and found to correlate to significantly worse mortality and cardiac events at 1 year. Troponin increases were asymptomatic, and there was no evidence that intervention improved outcome 14 …”

mentioning

confidence: 95%

Carotid artery stenting: where are we up to with evidence‐based practice?

Mohan

Naylor

2012

ANZ Journal of Surgery

View full text Add to dashboard Cite

Impact of troponin 1 on long‐term mortality after emergency orthopaedic surgery in older patients

Abstract: Elevated post-operative troponin levels are predictive of 1-year but not 2-year mortality in older patients undergoing emergency orthopaedic surgery.

Cited by 13 publications

References 20 publications

Isolated cardiac troponin rise does not modify the prognosis in elderly patients with hip fracture

Isolated cardiac troponin rise does not modify the prognosis in elderly patients with hip fracture

Perioperative myocardial necrosis in patients at high cardiovascular risk undergoing elective non-cardiac surgery

Carotid artery stenting: where are we up to with evidence‐based practice?

Contact Info

Product

Resources

About