2008
DOI: 10.1161/circulationaha.107.752113
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Impact of Time of Presentation on the Care and Outcomes of Acute Myocardial Infarction

Abstract: Background-Prior studies have demonstrated an inconsistent association between patients' arrival time for acute myocardial infarction (AMI) and their subsequent medical care and outcomes. Methods and Results-Using a contemporary national clinical registry, we examined differences in medical care and in-hospital mortality among AMI patients admitted during regular hours (weekdays 7 AM to 7 PM) versus off-hours (weekends, holidays, and 7 PM to 7 AM weeknights).

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Cited by 126 publications
(149 citation statements)
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References 23 publications
(30 reference statements)
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“…Specific studies in patients with acute myocardial infarction, ischemic stroke and the Intensive Care Units showed higher rate of clinical complications and hospital mortality in the "off-hours" periods (nighttime or weekends) [4][5][6][7][8][9][10][11][12] . The volume of evidence demonstrating higher incidence of unfavorable outcomes in these adverse conditions weakens the idea of occasional errors as the cause of these events [4][5][6][7][8][9][10] . This highlights the need to analyze these situations trough of a model to interpret the error with a systemic view.…”
mentioning
confidence: 99%
See 1 more Smart Citation
“…Specific studies in patients with acute myocardial infarction, ischemic stroke and the Intensive Care Units showed higher rate of clinical complications and hospital mortality in the "off-hours" periods (nighttime or weekends) [4][5][6][7][8][9][10][11][12] . The volume of evidence demonstrating higher incidence of unfavorable outcomes in these adverse conditions weakens the idea of occasional errors as the cause of these events [4][5][6][7][8][9][10] . This highlights the need to analyze these situations trough of a model to interpret the error with a systemic view.…”
mentioning
confidence: 99%
“…The cumulative presence of a number of unfavorable conditions is remarkable and very common in these periods, situations that favor and increase vulnerability to error [1][2][3][4][5][6][7][8][9][10] . Specific studies in patients with acute myocardial infarction, ischemic stroke and the Intensive Care Units showed higher rate of clinical complications and hospital mortality in the "off-hours" periods (nighttime or weekends) [4][5][6][7][8][9][10][11][12] . The volume of evidence demonstrating higher incidence of unfavorable outcomes in these adverse conditions weakens the idea of occasional errors as the cause of these events [4][5][6][7][8][9][10] .…”
mentioning
confidence: 99%
“…presenting during the night; outcomes, however, differ regarding in-hospital mortality [3][4][5][6][7] .…”
mentioning
confidence: 99%
“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] A number of prior analyses have suggested that the introduction of care components similar to elements in our intervention may lead to reductions in hospital length of stay. For instance, improved night and weekend physician coverage has been associated with reduced length of stay.…”
Section: Discussionmentioning
confidence: 99%
“…Compared to care on weekdays, care on weekends has been associated with delays, 1,2 decreased intensity, 3,4 and poorer performance on quality-of-care metrics such as time to reperfusion for acute myocardial infarction and completion of discharge instructions. [5][6][7][8][9][10][11] This variability in care may have important clinical implications, as weekends in the hospital have been associated with increased mortality. [8][9][10][11][12][13][14][15] At our medical center, we observed that the number of discharges was substantially lower on weekends than on weekdays.…”
Section: Introductionmentioning
confidence: 99%