Impact of the National Lung Screening Trial (NLST) publication and Medicare Lung cancer screening payment on lung cancer incidence rates: An interrupted time series analysis

Emmerick, Isabel Cristina Martins; Uy, Karl; Guiab, Keren; Powers, Maggie M.; Lou, Feiran; Lin, Poliana; Maxfield, Mark W.; Voland, R.; Varlotto, John M.

doi:10.1016/j.jcpo.2021.100318

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…The impact of CT screening on lung cancer incidence rates, mortality, and the percentage of early stage diagnosis was quantified by Emmerick et al [78] through a retrospective analysis of the SEER−18 time series over the period 2006-2016. The analysis considered indicators such as age, gender, race, marital status, insurance status, and household income.…”

Section: Literature Reviewmentioning

confidence: 99%

New Regional Dynamic Cancer Model across the European Union

Negoiță

Ionescu

Zlati

et al. 2023

Cancers

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Background: Can increasing levels of economic wealth significantly influence changes in cancer incidence and mortality rates? Methods: We investigated this issue by means of regression analyses based on the study of incidence and mortality indicators for lip, oral cavity, and pharyngeal; colon; pancreatic; lung; leukaemia; brain and central nervous system cancers in correlation with the levels of economic welfare and financial allocations to health at the level of the European Union member states, with the exception of Luxembourg and Cyprus for which there are no official statistical data reported. Results: The results of the study showed that there were significant disparities both regionally and by gender, requiring corrective public policy measures that were formulated in this study. Conclusions: The conclusions highlight the main findings of the study in terms of the evolution of the disease, present the significant aspects that characterise the evolution of each type of cancer during the period analysed (1993–2021), and highlight the novelty and limitations of the study and future directions of research. As a result, increasing economic welfare is a potential factor in halting the effects of cancer incidence and mortality at the population level, while the financial allocations to health of EU member countries’ budgets are a drawback due to large regional disparities.

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Section: Literature Reviewmentioning

confidence: 99%

New Regional Dynamic Cancer Model across the European Union

Negoiță

Ionescu

Zlati

et al. 2023

Cancers

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“…The above data are warning that lung cancer poses a serious threat to the lives of patients. Characterized by low differentiation, rapid growth, long doubling time, and extensive metastasis, SCLC is one of the tumors with the highest malignant degree in lung cancer, which can produce a variety of active hormones and neuroendocrine markers [ 4 , 5 ]. Most patients have distant metastasis at the first diagnosis, which is generally not suitable for surgical treatment; although SCLC is sensitive to radiotherapy and chemotherapy, the drug resistance occurs soon, thus leading to the disease progression [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Study on Effects of Cyclophosphamide Combined with Vinorelbine in Advanced Small Cell Lung Cancer and Anteroposterior Changes in MRI

Li¹,

Ren

2022

Contrast Media & Molecular Imaging

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Objective. To explore the effects of cyclophosphamide combined with vinorelbine in advanced small cell lung cancer (SCLC) and anteroposterior changes in MRI. Methods. The clinical data of 90 patients with advanced SCLC admitted to our hospital from April 2020 to April 2021 were retrospectively analyzed. They were divided into the control group and the study group according to the order of admission, with 45 cases in each group. The control group received the routine treatment, while the study group was treated with cyclophosphamide and vinorelbine to compare the indexes of imaging data and clinical indicators between the two groups before and after treatment. Results. There was no significant difference in the indexes of imaging data between the two groups before treatment P > 0.05 , and the indexes of imaging data in the study group were visibly lower than those in the control group after treatment P < 0.001 . The DCR in the study group was significantly higher than that in the control group after treatment P < 0.05 , while the QLQ-C30 scores and serum indices of the study group after treatment were significantly lower than those of the control group P < 0.001 . Conclusion. Patients with advanced SCLC were treated with cyclophosphamide and vinorelbine, which can effectively improve the quality of life and reduce the expression of inflammatory factors. This treatment model has a higher application value, and the treatment value is also reflected compared with the routine treatment. At the same time, the permeability parameters obtained by MRI can predict the therapeutic effects of cyclophosphamide and vinorelbine, and further studies are helpful to establish a better solution for patients.

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Impact of the National Lung Screening Trial (NLST) publication and Medicare Lung cancer screening payment on lung cancer incidence rates: An interrupted time series analysis

Cited by 2 publications

References 24 publications

New Regional Dynamic Cancer Model across the European Union

New Regional Dynamic Cancer Model across the European Union

Study on Effects of Cyclophosphamide Combined with Vinorelbine in Advanced Small Cell Lung Cancer and Anteroposterior Changes in MRI

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