Impact of smoking on acute phase outcomes of myocardial infarction

Abstract

A beneficial effect of smoking ('smoker's paradox') in the unadjusted primary end point continues to be present; however, after adjustment for differences in baseline characteristics, no benefit was detectable.

Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI

“…However, it is also well known that smokers are at greater risk for development of cancer and other pulmonary disease during followup. Although this issue might be relevant to the low early cardiac mortality and late noncardiac mortality in our study, our data do not allow an assessment of the proportion of habitual smokers, and recent studies do not support the existence of a "smoker's paradox" (24,25).…”

Smoking and infarct size among STEMI patients undergoing primary angioplasty

“…When these baseline differences were corrected for by multivariate analysis, smoking status was no longer an independent predictor of survival. Similarly, in a recent study including 1424 STEMI patients undergoing rescue or primary angioplasty, Wakabayashi et al [25], found a beneficial effect of smoking on clinical outcome, that disappeared after adjustment for differences in baseline characteristics. However, Katayama et al [26], among 367 STEMI patients undergoing primary angioplasty, found that smoking was associated with lower mortality rates, potentially explained by less damage to the microvascular function (as evaluated by ST-segment resolution) and better ejection fraction.…”

SMOKING AS A RISK FACTOR OF CARDIOVASCULAR AND CEREBROVASCULAR DISEASES: PREVALENCE, IMPACT ON PROGNOSIS, POSSIBLE SMOKING CESSATION STRATEGIES AND THEIR EFFECTIVENESS. Part 1. Smoking Prevalence and Impact on Prognosis

“…Wakabayashi K. с соавт. [31] про-анализировали данные 1424 больных с ИМ, которым были выполнены чрезкожные коронарные вмеша-тельства с установкой стентов с лекарственным по-крытием, и которых они разделили на 3 группы, в том числе -курящих на момент развития ИМ (n=486), бросивших курить (n=349) и никогда не куривших (n=589). Авторы также выявили, что курящие паци-енты были достоверно моложе по сравнению с нико-гда не курившими (p<0,001).…”