Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: the Nagahama study

Matsumoto, Takeshi; Murase, Kimihiko; Tabara, Yasuharu; Gozal, David; Smith, Dale L.; Minami, Takuma; Tachikawa, Ryo; Tanizawa, Kiminobu; Oga, Toru; Nagashima, Shunsuke; Wakamura, Tomoko; Komenami, Naoko; Setoh, Kazuya; Kawaguchi, Takahisa; Tsutsumi, Takanobu; Takahashi, Yoshimitsu; Nakayama, Takeo; Hirai, Toyohiro; Matsuda, Fumihiko; Chin, Kazuo

doi:10.1093/sleep/zsy071

Cited by 53 publications

(42 citation statements)

References 43 publications

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“…A recent study from Japan investigated the link between sleep quality and diabetes among 3249 diabetic patients (<20 years) using the Pittsburgh Sleep Quality Index (PSQI); these patients were found to have poor subjective sleep quality due to increased sleep latency and a shorter duration of sleep [95]. The short duration of sleep is associated with increased incidence of T2DM as well as poor metabolic control in both type 1 and type 2 DM [26]. Though the purpose of this review is not to address other therapeutic modalities for the treatment of diabetes, one should bear in mind that for a holistic approach, weight loss (e.g., dietary and lifestyle modifications) and surgical options are available.…”

Section: Discussionmentioning

confidence: 99%

The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus

Chattu

Burman

et al. 2019

Healthcare

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For healthy existence, humans need to spend one-third of their time sleeping. Any qualitative or quantitative disturbances in sleep would result in an increased prevalence of obesity, metabolic disorders, diabetes, cardiovascular diseases, and hypertension. The paper aims to highlight the growing global problem of insufficient sleep and its significant impact on the rising incidence of diabetes mellitus. An extensive literature search was done in all major databases for “insufficient sleep” and “Diabetes Mellitus” for this review. Shorter (<6 h) and longer (>9 h) durations of sleep have been adversely related to insulin resistance. Though the relation between insufficient sleep and diabetes mellitus is more or less understood, little is known about how oversleeping or hypersomnia (10–12 h) increases the risk of diabetes. The relationship between sleep disturbances and diabetes is dual-sided, as chronic sleep disturbances would elevate the risk of developing insulin resistance, while diabetes would worsen the quality of sleep. Both the qualitative and quantitative disturbances in sleep significantly increase the risk of developing diabetes, which is supported by numerous community-based and hospital-based epidemiological studies discussed in this review. Obstructive sleep apnea is one of the most common sleep disorders and is characterized by chronic intermittent hypoxia and increased sympathetic activity, thus leading to a higher prevalence of diabetes. Sleep therapy may serve as a low-cost method for fighting against the rising epidemic of diabetes.

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Section: Discussionmentioning

confidence: 99%

The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus

Chattu

Burman

et al. 2019

Healthcare

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“…To test this hypothesis we investigated the associations between SDB and the prevalence of diabetes, the prevalence of recent-onset diabetes determined in the study's most recent 5 years, and insulin resistance among study participants with or without an FHD in the Nagahama Cohort. 17 Preliminary findings have been previously reported in abstract form. 22…”

Section: Introductionmentioning

confidence: 79%

“…[14][15][16] Previously, we showed that the impact of SDB on the prevalence of diabetes was modified by gender and menopausal status. 17 These findings implied that the effect of SDB might vary according to an individual's genetic characteristics. Of the various factors related to glucose metabolism, a positive family history of diabetes (FHD) is a well-established strong risk factor for development of diabetes, 18 which also exhibits synergistic interactions in the presence of concurrent obesity.…”

Section: Introductionmentioning

confidence: 97%

Impact of sleep-disordered breathing on glucose metabolism among individuals with a family history of diabetes: the Nagahama study

Minami

Matsumoto

Tabara

et al. 2021

Journal of Clinical Sleep Medicine

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Study Objectives: It is well known that a family history of diabetes (FHD) is a definitive risk factor for type 2 diabetes. It has not been known whether sleep disordered breathing (SDB) increases the prevalence of diabetes in those with FHD. Methods:We assessed SDB severity in 7,477 study participants by oximetry corrected by objective sleep duration determined by wrist actigraphy. HbA1c ≥6.5% and/or current medication for diabetes indicated the presence of diabetes. In addition to the overall prevalence, the prevalence of recent-onset diabetes during the almost 5 years before the SDB measurements was investigated.Results: Of the 7,477 participants (mean age 57.9 [range 34.2-80.7, SD 12.1] years, females 67.7%), 1,569 had FHD. The prevalence of diabetes in FHD participants with moderate-to-severe SDB (MS-SDB) was higher than in those without SDB (MS-SDB vs.

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“…Benjafield reported that 936 million adults aged 30–69 years had mild to severe OSA and 425 million had moderate to severe OSA [ 3 ]. In addition to that report, recent reports showed that more than 20% of middle-aged adult males and nearly 10% of post-menopausal females had moderate to severe OSA [ 4 ]. Therefore, it is important to evaluate COVID-19 management from the viewpoint of OSA because risk factors for OSA mimic the risk factors for COVID-19.…”

mentioning

confidence: 92%

Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: the Nagahama study

Abstract: Notwithstanding the cross-sectional design, SDB and obesity, but not short sleep duration, were independently associated with diabetes and hypertension, with gender and menopausal status-related differences in risk emerging.

Cited by 53 publications

References 43 publications

The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus

The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus

Impact of sleep-disordered breathing on glucose metabolism among individuals with a family history of diabetes: the Nagahama study

Might CPAP prevent exacerbation in patients with COVID-19 with or without obstructive sleep apnea?

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