Impact of Sinogram Affirmed Iterative Reconstruction (SAFIRE) Algorithm on Image Quality with 70 kVp-Tube-Voltage Dual-Source CT Angiography in Children with Congenital Heart Disease

Nie, Pei; Li, Haiou; Duan, Yi‐Shi; Wang, Ximing; Ji, Xiangling; Cheng, Zhaoping; Wang, Anbiao; Chen, Jiuhong

doi:10.1371/journal.pone.0091123

Cited by 28 publications

(14 citation statements)

References 27 publications

(32 reference statements)

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“…17 Few studies reported high-concentration contrast medium with lower injection rate application in CCTA. 20 The result of this study indicated that the application of prospective ECG-trigger high-pitch dual-source CCTA with three low scheme using SAFIRE could guarantee the quality of the image. Despite low-tube voltage could contribute to achieve radiation dose reduction, 18 but it in turn increased the noise of images, leading to the decrease in resolution.…”

Section: Discussionmentioning

confidence: 74%

“…19 Lately, SAFIRE was the secondgeneration IR algorithm delivered by Siemens, which could further effectively improve the image quality and reduce image artifacts as compared to the traditional filtered back projection (FBP) reconstruction algorithm. 20 The result of this study indicated that the application of prospective ECG-trigger high-pitch dual-source CCTA with three low scheme using SAFIRE could guarantee the quality of the image.…”

Section: Discussionmentioning

confidence: 74%

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Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Tang¹

2018

Echocardiography

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 74%

Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Tang¹

2018

Echocardiography

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“…With regards to the CT attenuation, which mainly relates to the tube voltage, the CT value is considerably larger in the lumen of the renal artery at 80 kVp than those at 120 kVp. Regarding image noise in this study, SAFIRE, as a novel reconstruction technique, is a raw-data-based iterative reconstruction algorithm that compares reconstructed and measured CT data in the raw data domain and iteratively corrects the images (21,22). However, image noise of renal artery CTA showed a considerably higher amount at 80 kVp than performed at 120 kVp, and it is believed that SAFIRE reconstruction can reduce the image noise at 80 kVp, and provide higher image quality of renal artery for patients with suspected renal mass at 80 kVp for clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Optimization of Scan and Reconstruction Parameters for Renal Artery CT Angiography with Iterative Reconstruction at Low kVp Compared with Filtered Back Projection at 120 kVp Acquisition

et al. 2018

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Background: As cross-sectional images expanded in clinical practice, the number of renal lesions discovered incidentally has been increasing. CT protocols for renal mass evaluation may include pre-and post-contrast phase. However, a major concern with respect to those multiphase techniques is often the involvement of radiation dose. One further critical issue is how to minimize the radiation dose for patients and provide optimizational image quality for radiologists in clinical work. Objectives: To evaluate the image quality and radiation dose of renal artery CT angiography (CTA) with optimal sinogram affirmed iterative reconstruction (SAFIRE) strength level at 80 kVp for optimizing the scan and reconstruction parameters of renal artery CTA, in comparison to 120 kVp acquisition with filtered back projection (FBP). Patients and Methods: Sixty consecutive patients were classified into three groups prospectively in this study: 1) 80 kVp group (n = 30) with FBP and 2) 80 kVp group with SAFIRE (S4) and 3) 120 kV group (n = 30) with FBP. CT values and noise were measured, contrastto-noise ratio (CNR) and signal-to-noise ratio (SNR) of the renal artery CTA were calculated for quantitative assessment. Subjective image quality was evaluated by two experienced abdominal radiologists with a five-point scale in a blinded and randomized setting for qualitative assessment. Volume CT dose index (CTDIvol) and size-specific dose estimate (SSDE) were calculated and estimated for each subject presented in this study. Results: As for quantitative assessment, CNR, SNR and CT values of renal artery in 80kVp group with SAFIRE strength levels or FBP were higher than those of 120 kVp group with FBP (all Ps < 0.05), the mean noise gradually decreased in 80kVp group when increasing the SAFIRE strength levels (S1~S5). As for qualitative assessment, the overall image quality, vessel sharpness, segmental renal artery displayed in MIP or MPR, and diagnostic confidence of the two groups were all accepted by two radiologists (inter-observer

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“…Several studies in children have shown that IR algorithms enable reduced radiation doses with maintained or improved image quality. CT studies in pediatric population, including those with congenital heart disease (CHD) have shown higher image quality, lower noise, and maintained diagnostic accuracy in ultra-low dose studies (using 70 kVp/half tube current/ high pitch helical mode) reconstructed with SAFIRE or IRIS compared to FBP reconstructions, with up to 54% radiation dose savings and effective radiation doses <0.1 mSv (27)(28)(29)(30). Other pediatric CT studies using ASIR demonstrated improved conspicuity of various pediatric cardiovascular structures in newborns and children compared to FBP with 36% dose reduction as long as ASIR levels were low (20-40%) (31); ASIR at higher (>50%) levels resulted in lower image quality with image conspicuity very poor due to noise free appearance of structures at 100% ASIR (31).…”

Section: Decreased Radiation Dosementioning

confidence: 99%

The role of advanced reconstruction algorithms in cardiac CT

Halliburton

Tanabe

Partovi

et al. 2017

Cardiovasc. Diagn. Ther.

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Advanced non-linear iterative reconstruction (IR) algorithms have been introduced by all vendors as an alternative to traditional, linear filtered back projection (FBP) reconstruction ( Table 1). FBP is a simple reconstruction technique that requires relatively little computational processing, but is associated with higher noise and poor contrast resolution. Noise can be reduced in FBP only by increasing the radiation dose. IR algorithms operate by initially generating an expected dataset based on modeling, which is then compared to the actual, acquired dataset. Noise is detected and removed by using the difference between the anticipated and actual datasets using a process of iterative steps. All commercial IR algorithms employ statistics-model based de-noising in the image domain, raw (projection) data domain, or both. Statistics model-based algorithms operate by assigning a lower value to data with higher statistical uncertainty (noise). Some IR algorithms, described as partial model-based, additionally employ models of scanner geometry to estimate the acquired data. Full model-based IR algorithms, employ complete system models that include simulation of X-ray interaction with the imaged object. Statistics-model based algorithms can be utilized to either improve image quality at the same radiation dose or maintain image quality at a lower radiation dose compared to FBP. However, combining dose management with image quality improvements simultaneously is limited. Model-based IR can provide image quality improvements at lower doses. Model-based algorithms are also more likely to reduce other artifacts in addition to noise as well as improve spatial resolution.Although IR algorithms have been utilized in nuclear medicine for several decades, widespread use in CT is recent and facilitated by advances in computational processing. Cardiovascular CT imagers were early adopters of IR algorithms because most cardiovascular clinical targets are robust to changes in noise. Rigorous validation has come from both retrospective and prospective studies demonstrating non-inferiority of coronary CT data acquired at lower doses and reconstructed with IR techniques compared to standard dose data reconstructed with FBP. Other clinical studies have validated the diagnostic utility of low-dose coronary CT angiograms (CTA) reconstructed with IR algorithms using invasive coronary angiography (ICA) as a standard of reference (1-3).

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Impact of Sinogram Affirmed Iterative Reconstruction (SAFIRE) Algorithm on Image Quality with 70 kVp-Tube-Voltage Dual-Source CT Angiography in Children with Congenital Heart Disease

Cited by 28 publications

References 27 publications

Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Optimization of Scan and Reconstruction Parameters for Renal Artery CT Angiography with Iterative Reconstruction at Low kVp Compared with Filtered Back Projection at 120 kVp Acquisition

The role of advanced reconstruction algorithms in cardiac CT

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