Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Tang, Zhengyi

doi:10.1111/echo.14036

Cited by 2 publications

(4 citation statements)

References 19 publications

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“…The present study demonstrated that CM volume could be reduced to 30 mL in patients with a relatively low BSA while retaining 100% acceptable DIQ (Figure 2). This is consistent with the findings of previous studies worldwide (3,(9)(10)(11)(12)(14)(15)(16)(29)(30)(31)(32), which have focused on optimizing CM dosage to achieve DIQ with CCTA. Feng et al (15) demonstrated successful imaging using a total of 28 mL CM (370 mgI/mL) with an IFR of 3.5 mL/s in prospective highpitch CCTA; therefore, the successful use of 30 mL CM for CCTA imaging should not be surprising.…”

Section: Discussionsupporting

confidence: 92%

“…The first 53 patients were enrolled in the lowdose (LD) group, and the next 50 participants were enrolled in the routine-dose (RD) group. The LD group received 30 mL of CM and 60 mL of saline at an IFR of 3.5 mL/s; the RD group was administered CM according to their weight (0.7 mL/kg) (11). The IFR of the CM for the RD group was calculated as the volume divided by 10 s, consistent with the IFR of saline.…”

Section: Patient Populationmentioning

confidence: 99%

“…Lowering the CM dose while maintaining a constant injection duration lowers the IFR, decreasing the iodinated delivery rate (IDR), directly influencing the DIQ of CCTA images (5). Maintaining DIQ within a satisfactory range while using a relatively low dose of ICM has been the subject of many studies (3,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17). Vascular attenuation during CCTA is influenced by several patient-specific factors, including body mass, blood volume, cardiac output, and factors related to the procedure, such as the administered CM concentration and injection rate (18).…”

Section: Introductionmentioning

confidence: 99%

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Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 m2

Jin¹,

Jie²,

Gao³

et al. 2021

Quant Imaging Med Surg

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Background: Reducing contrast media volume in coronary computed tomography angiography minimizes the risk of adverse events but may compromise diagnostic image quality. We aimed to evaluate coronary computed tomography angiography's diagnostic image quality while using 30 mL of contrast media in patients with a body surface area <1.7 m 2 .Methods: This prospective study included patients who underwent coronary computed tomography angiography from May 2018 to June 2019. The patients were divided into a low-dose group, who received 30 mL of contrast media, and a routine-dose group, who received contrast media based on body weight.Patient characteristics, coronary computed tomography angiography results, and quantitative and qualitative image results were assessed and compared.Results: In total, 103 patients with a body surface area <1.7 m 2 were 53 in the low-dose group and 50 in the routine-dose group. Sex, age, body surface area, body weight, and heart rate were similar between the groups (P>0.05). A contrast media volume of 30±0 mL was used for the low-dose group, and 41.62±4.59 mL was used for the routine-dose group. The low-dose group's computed tomography values were significantly different from those of the routine-dose group (P<0.05). The radiologists demonstrated agreement regarding diagnostic image quality and accuracy (kappa =0.91 and 0.85, respectively).Conclusions: Using 30 mL of contrast media for coronary computed tomography angiography in patients with a body surface area <1.7 m 2 provided a suitable diagnostic image quality for coronary artery disease diagnosis. Although radiation doses were similar between the groups, the decreased contrast media volume was likely beneficial for the patients.

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Section: Discussionsupporting

confidence: 92%

Section: Patient Populationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 m2

Jin¹,

Jie²,

Gao³

et al. 2021

Quant Imaging Med Surg

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“…Most protocols for CM administration are based on body mass index (BMI) or body weight 7,8,14,17,18 . Some more recent protocols have been based on the patient's blood volume 9 or use a high delivery rate 13 .…”

Section: Pvatmentioning

confidence: 99%

Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners

Jin

Gao

Sun

et al. 2020

Sci Rep

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We evaluated the feasibility and image quality of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA) using a body surface area (BSA) protocol for contrast-medium (CM) administration on both second- and third-generation scanners (Flash and Force CT), without using heart rate control. One-hundred-and-eighty patients with suspected coronary heart disease undergoing CCTA were divided into groups A (BSA protocol for CM on Flash CT), B (body mass index (BMI)-matched patients; BMI protocol for CM on Flash CT), and C (BMI-matched patients; BSA protocol for CM on Force CT). Patient characteristics, quantitative and qualitative measures, and radiation dose were compared between groups A and B, and A and C. Of the 180 patients, 99 were male (median age, 62 years). Average BSA in groups A, B, and C was 1.80 ± 0.17 m2, 1.74 ± 0.16 m2, and 1.64 ± 0.17 m2, respectively, with groups A and C differing significantly (P < 0.001). Contrast volume (50.50 ± 8.57 mL vs. 45.00 ± 6.18 mL) and injection rate (3.90 ± 0.44 mL/s vs. 3.63 ± 0.22 mL/s) differed significantly between groups A and C (P < 0.001). Groups A and C (both: all CT values > 250 HU, average scores > 4) achieved slightly lower diagnostic image quality than group B. The BSA protocol for CM administration was feasible in both Flash and Force CT, and therefore may be valuable in clinical practice.

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Application of double low dose combined low flow injection in coronary dual‐source coronary computed tomography angiography

Abstract: The prospective ECG-triggered high-pitch dual-source CCTA with low voltage, contrast medium, and flow rate injection using sinogram affirmed iterative reconstruction is feasible which can observably reduce radiation and obtain satisfactory images.

Cited by 2 publications

References 19 publications

Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 m2

Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 m2

Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners

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