Impact of short-term air pollution exposure on acute coronary syndrome in two cohorts of industrial and non-industrial areas: A time series regression with 6,000,000 person-years of follow-up (ACS - Air Pollution Study)

Kuźma, Łukasz; Wańha, Wojciech; Kralisz, Paweł; Kaźmierski, Maciej; Bachórzewska−Gajewska, Hanna; Wojakowski, Wojciech; Dobrzycki, Sławomir

doi:10.1016/j.envres.2021.111154

Cited by 19 publications

(19 citation statements)

References 35 publications

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“…Will it be temporary or permanent is a matter of research in the near future, but biomarkers of cardiac injury in SARS-CoV-2-infected patients usually decrease after a longer period of time, which can suggest direct cardiac damage caused by the virus [7]. However, it is known that there are various reasons for cardiac injury [64], and it can be caused by other viruses, for example, influenza virus [65,66]. Generally, infection increases the risk of cardiovascular events, such as acute myocardial infarction [67], and may deteriorate or trigger cardiovascular disease [68][69][70].…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular System during SARS-CoV-2 Infection

Koźlik

Błahuszewska

Kaźmierski

2022

IJERPH

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SARS-CoV-2 virus can not only damage the respiratory system but may also pose a threat to other organs, such as the heart or vessels. This review focuses on cardiovascular complications of COVID-19, including acute cardiac injury, arrhythmias, biomarkers, accompanying comorbidities and outcomes in patients diagnosed with SARS-CoV-2 infection. The research was conducted on the databases: PubMed, Springer, ScienceDirect, UpToDate, Oxford Academic, Wiley Online Library, ClinicalKey. Fifty-six publications from 1 November 2020 till 15 August 2021 were included in this study. The results show that cardiac injury is present in about 1 in 4 patients with COVID-19 disease, and it is an independent risk factor, which multiplies the death rate several times in comparison to infected patients without myocardial injury. New-onset cardiac injury occurs in nearly every 10th patient of the COVID-19-suffering population. Comorbidities (such as hypertension, cardiovascular disease and diabetes) severely deteriorate the outcome. Therefore, patients with SARS-CoV-2 infection should be carefully assessed in terms of cardiac medical history and possible cardiological complications.

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Section: Discussionmentioning

confidence: 99%

Cardiovascular System during SARS-CoV-2 Infection

Koźlik

Błahuszewska

Kaźmierski

2022

IJERPH

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“…Time-series analyses of PM-related morbidity in Poland are still rare and, to the authors' knowledge, until the end of 2021, no paper was published that included an analysis of the risk of hospitalizations with the use of GAM models. Several studies have applied other time-series methods to calculate air-pollution-related morbidity risks in individual cities [37][38][39], single voivodeships [40] or several selected locations [41][42][43][44][45], but none of them included a multi-city meta-analysis.…”

Section: Discussionmentioning

confidence: 99%

Ambient Particulate Air Pollution and Daily Hospital Admissions in 31 Cities in Poland

Adamkiewicz¹,

Maciejewska

Rabczenko

et al. 2022

Atmosphere

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A strong and consistent association has been observed between morbidity or mortality rates and PM concentration, and is well documented in many countries. In Poland, despite poor air quality, studies concerning the evaluation of acute health effects of ambient air pollution on morbidity from respiratory or cardiovascular diseases are rare. We examined the short-term impact of PMx concentration on hospital admission in 31 Polish cities based on the daily PM10, PM2.5 concentration, meteorological variables, and hospital data. The generalized additive model (GAM) and a random-effects meta-analysis were used to assess the impact of air pollution on morbidity within the exposed population. Almost 1.6 million cardiovascular admissions and 600 thousand respiratory disorders were analyzed. The RR values for PM10-related cardiovascular and respiratory hospital admissions in Poland are equal to 1.0077 (95% confidence interval, 1.0062 to 1.0092) and 1.0218 (95% confidence interval, 1.0182 to 1.0253), respectively, while for PM2.5 1.0088 (95% confidence interval, 1.0072 to 1.0103) and 1.0289 (95% confidence interval, 1.0244 to 1.0335), respectively. Moreover, a moderate heterogeneity of RR estimates was observed between the analyzed cities (I2 values from 27% to 45%). The presented analysis confirms the significant association between hospital admission and PMx concentration, especially during heating seasons.

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“…Epidemiological data has suggested that fine particulate matter has much more obvious toxic cardiovascular effects than gaseous pollutants. High levels of PM 2.5 and PM 10 were associated with an increased risk of ACS in Italy, China, New York, and Poland [ 74 – 78 ]. In Italy, a 10 μg/m 3 increase in PM 2.5 levels caused a 2.3% rise in the risk of ACS, while in China, high concentrations of PM 2.5 determined an increase in cardiovascular morbidity and mortality [ 74 , 75 ].…”

Section: The Impact Of Air Pollution On Acute Coronary Syndromementioning

confidence: 99%

“…A 10 μg /m 3 increase in PM 10 concentration was associated with high UA hospitalizations [ 77 ]. In industrial areas of Poland, exposure to high levels of gaseous pollutants (NO 2 , SO 2 , CO) and fine particulate matter (PM 10 , PM 2.5 ) increased the incidence of STEMI, while NSTEMI hospitalizations were related to high NO 2 concentrations in both industrial and non-industrial areas [ 78 ]. Data on the importance of O 3 on ACS is inconclusive [ 79 , 80 ].…”

Section: The Impact Of Air Pollution On Acute Coronary Syndromementioning

confidence: 99%

The Impact of Meteorological Factors and Air Pollutants on Acute Coronary Syndrome

Rus

Mornos

2022

Curr Cardiol Rep

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Purpose of Review Several studies have found that air pollution and climate change can have an impact on acute coronary syndromes (ACS), the leading cause of death worldwide. We synthesized the latest information about the impact of air pollution and climate change on ACS, the latest data about the pathophysiological mechanisms of meteorological factors and atmospheric pollutants on atherosclerotic disease, and an overall image of air pollution and coronary heart disease in the context of the COVID-19 pandemic. Recent Findings The variation of meteorological factors in different seasons increased the risk of ACS. Both the increase and the decrease in apparent temperature were found to be risk factors for ACS admissions. It was also demonstrated that exposure to high concentrations of air pollutants, especially particulate matter, increased cardiovascular morbidity and mortality. Summary Climate change as well as increased emissions of air pollutants have a major impact on ACS. The industrialization era and the growing population cause a constant increase in air pollution worldwide. Thus, the number of ACS favored by air pollution and the variations in meteorological factors is expected to increase dramatically in the next few years.

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Impact of short-term air pollution exposure on acute coronary syndrome in two cohorts of industrial and non-industrial areas: A time series regression with 6,000,000 person-years of follow-up (ACS - Air Pollution Study)

Cited by 19 publications

References 35 publications

Cardiovascular System during SARS-CoV-2 Infection

Cardiovascular System during SARS-CoV-2 Infection

Ambient Particulate Air Pollution and Daily Hospital Admissions in 31 Cities in Poland

The Impact of Meteorological Factors and Air Pollutants on Acute Coronary Syndrome

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