Impact of Prehypertension on Carotid Artery Intima Media Thickness

Mandal, Bidhan Ch.; Pramanik, Subhra Prakash; Bag, Arijit; Sarkar, Niladri

doi:10.9790/3013-0404.08-10

Cited by 1 publication

(2 citation statements)

References 9 publications

(5 reference statements)

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“…Despite the reference value of mean cIMT, various studies done in past found that cIMT was significantly higher in HTN not accounting for any treatment than that of the the healthy group. 1,3,9,14,17,[19][20][21][22] The results of these studies are similar to our study. Also, the mean cIMT in study done by Mandal et al 22 for hypertensive patient is within the range of our result.…”

Section: Discussionsupporting

confidence: 89%

“…1,3,9,14,17,[19][20][21][22] The results of these studies are similar to our study. Also, the mean cIMT in study done by Mandal et al 22 for hypertensive patient is within the range of our result. Lianget al 23 also found that mean cIMT was increased in both smoking andHypertensive patient with increased the IMT/ Lumen ratio in HTN while smoking had no effect on this ratio proving that HTN has more additive effect on cIMT than other risk factors like smoking.…”

Section: Discussionsupporting

confidence: 89%

See 1 more Smart Citation

Sonographic evaluation of Intima-Media thickness of carotid artery in healthy, hypertensive and diabetic Nepalese population

Regmi

Sharma

Khadka

2020

J. Gandaki Med. Coll. Nepal

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Introduction: Hypertension and Diabetes are two major risk factors for atherosclerotic disease. Carotid artery intima media thickness(cIMT) is considered a reliable surrogate measure for diagnosing subclinical atherosclerosis, its progression and regression. Paucity of available data regarding mean value of cIMT highlights the importance of defining the cut off value of cIMT in a specified population. Very limited studies have been done on sonographic evaluation of mean cIMT and carotid artery injury in hypertension and diabetes in Nepalese population. This study, therefore aims to determine mean cIMT in Nepalese population and to analyze effect of Hypertension and diabetes on cIMT. Methods: Cross-sectional hospital based study was conducted within the period of 18 months. B-mode ultrasound was used to measure cIMT in bilateral common carotid arteries. Comparison of mean cIMT was done amongst healthy, hypertensive and diabetes with hypertensive patients. Duration of disease was also considered. Data analysis was done with “R” analytical study. Results were expressed as mean ± standard deviation. Results: Total1005 (508 female and 497 male) adult patients with age range of 30 to 85 years were assessed. Among these 329(32.74%) were healthy adults, 341(33.93%) were hypertensive and 335(33.33%) were diabetes with hypertensive patients. The mean cIMT in cases was more than controls (P < 0.001) bilaterally with diabetes having an additive effect. There was also positive correlation of measured value with duration of disease and age of patients. Conclusion: The present study found that mean cIMT in cases was more than controls. There is an additional effect of Diabetes on cIMT in hypertensive patient. Age and duration of disease can accelerate atherosclerosis.

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