Impact of Positive Pressure Treatment of the Airway on Health-Related Quality of Life in Elderly Patients With Obstructive Sleep Apnea

Merino, J; Torres, Luis Ángel Pérula de; Bardwell, Wayne A.; Gómez, Rafaela Muñoz; Villalobos, Ana Roldán; Collado, Nuria Feu; Moral, Roger Ruiz; Jurado-Gámez, Bernabé; Investigators, Calidad Vida Continuous Positive Airway Pressure

doi:10.1177/1099800418774633

Cited by 10 publications

(7 citation statements)

References 29 publications

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“…Of all the possible therapeutic modalities, continuous positive airway pressure (CPAP) therapy still remains the gold standard in OSAS therapy 7 . CPAP therapy leads to an improvement in quality of life 8 , and may reduce certain health risks if the adherence of the patient is sufficient 9,10 . Sufficient adherence is defined by most studies as the use of CPAP for over 4 hours per night on average, however it is unclear if such adherence is enough to achieve the full extent of the possible benefits of the therapy 11 .…”

Section: Introductionmentioning

confidence: 99%

Adherence of obstructive sleep apnoea syndrome patients to positive airway pressure therapy - 10-year follow-up

Genzor¹,

Praško²,

Vaněk³

et al. 2022

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Purpose. Continuous positive airway pressure (CPAP) is the most effective therapy for obstructive sleep apnoea syndrome (OSAS). Long-term adherence is necessary; however, it may be widely variable based on current literature, where the predicting factors are also not well defined. The aim of this study was to assess ten-year adherence to CPAP and to define factors influencing it. Methods. In total, 107 patients (91 males) were enrolled in this study, with an average age of 53.5 years (SD 10.1), with CPAP therapy being indicated (Apnoea-Hypopnoea Index -AHI > 15). Anthropometric and social status data have been obtained as well as the average use of CPAP through device memory. Results. Sufficient adherence (> 4 hours per night) was found in 57% of patients in the first year with no subsequent significant change during the next 9 years. Adherence correlated significantly with the severity of OSAS -AHI (r = 0.321 over 5 years) and Epworth Sleepiness Scale (r = 0.317 over ten years) but did not correlate with the pressure used or the age of the patient. No statistically significant differences have been found between the sexes, the different mask groups, or the social status groups. Conclusion. Good adherence to CPAP therapy in OSAS patients is essential. According to our results, patients with more severe OSAS or more severe sleepiness seem to have better adherence.

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Section: Introductionmentioning

confidence: 99%

Adherence of obstructive sleep apnoea syndrome patients to positive airway pressure therapy - 10-year follow-up

Genzor¹,

Praško²,

Vaněk³

et al. 2022

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…Algunos investigadores afirman encontrar relación entre apnea obstructiva del sueño y calidad de vida de las personas de edad avanzada [5][6][7][8][9][10][11][12][13][14][15] .…”

Section: Resultados Sobre La Relación Apnea Obstructiva Del Sueño Y Calidad De Vida En Personas De Edad Avanzadaunclassified

“…La apnea obstructiva del sueño produce, en personas ancianas, según la mayoría de los estudios revisados [5][6][7][8][9][10][11][12][13][14][15] , un deterioro de la calidad de vida, aunque existe disparidad en los resultados, ya que ciertas investigaciones 17,18 afirman que a partir de cierta edad (70 años aproximadamente) se produce una estabilización en la calidad de vida de las personas que padecen apnea del sueño.…”

Section: Discussionunclassified

“…Comparar estos estudios resulta difícil, ya que los instrumentos (SF-36 8,14,16,17,19 , SAQLI 8,14 , QSQ 9,10 , EuroQoL-5D 12,20 , HRQOL 13 y SF-12 18 ) y/o metodologías (casos y controles 9,11 , cohortes 10,15,17 , revisión sistemática [5][6][7] , estudio transversal 12,13,16,18 , prospectivo 8,19 ) utilizados son distintos en muchos de ellos, al igual que las posibles comorbilidades asociadas (insuficiencia cardiaca 5,9,16 , hipertensión 5,16,17 , accidente cerebrovascular 5,9,11 , diabetes tipo 2 5,17 , síndrome locomotor 12 , etc.) a cada individuo.…”

Section: Discussionunclassified

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Calidad de vida en personas mayores con síndrome de apnea obstructiva del sueño. Revisión sistemática

Donaire¹

2021

Gerokomos

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“…A recent meta-analysis of data for 63,647 participants concluded that OSAS was an independent risk factor for DM after adjustment for age, sex, and body mass index (BMI) [13]. These observations are not surprising as OSAS and DM share the same risk factors, namely obesity and aging [14]. The high prevalence of OSAS in the DM population, between 23 and 48%, confirms this strong association [15].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of undiagnosed glucose intolerance and type 2 diabetes in patients with moderate-to-severe obstructive sleep apnea syndrome

2019

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Purpose Overweight and obesity are major causal factors for obstructive sleep apnea syndrome (OSAS), providing insight into why one third of patients with OSAS suffer from diabetes mellitus and another third from glucose intolerance. However, a significant proportion of the general population remains undiagnosed for glucose metabolism disorders. The primary aim of this study was to establish the prevalence of known and newly diagnosed glucose metabolism disorders in patients with moderate and severe OSAS referred to the sleep lab for continuous positive airway pressure (CPAP) therapy. Methods We prospectively included consecutive patients with moderate or severe OSAS referred for CPAP therapy. A fasting blood sample was collected to determine glycosylated hemoglobin (HbA1c), glucose, and homeostatic model assessment (HOMA) index. Baseline demographic data and medication intake were recorded. Results Of 280 consecutive patients (70% men, mean ± SD body mass index 33 ± 7 kg/m 2 , apnea-hypopnea index 49 ± 25), 22% exhibited diabetes and 44% glucose intolerance. Undiagnosed diabetes and glucose intolerance was found in 79 of 280 patients (28%). Insulin resistance was associated with OSAS severity in multivariate linear regression analysis (regression coefficient 2.40 [95% CI 0.07-4.72]; p = 0.04). Conclusion In this population of overweight and obese patients with moderate and severe OSAS, 66% of patients had diabetes or glucose intolerance and 28% were newly diagnosed. Diabetes and glucose intolerance were not related to OSAS severity, contrary to insulin resistance. These data suggest that there is value in systematic screening for glucose metabolism disorders in all patients with moderate and severe OSAS.

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Impact of Positive Pressure Treatment of the Airway on Health-Related Quality of Life in Elderly Patients With Obstructive Sleep Apnea

Abstract: Therapy with CPAP in elderly patients with OSA helps improve their HRQL and reduces daytime sleepiness.

Cited by 10 publications

References 29 publications

Adherence of obstructive sleep apnoea syndrome patients to positive airway pressure therapy - 10-year follow-up

Adherence of obstructive sleep apnoea syndrome patients to positive airway pressure therapy - 10-year follow-up

Calidad de vida en personas mayores con síndrome de apnea obstructiva del sueño. Revisión sistemática

Prevalence of undiagnosed glucose intolerance and type 2 diabetes in patients with moderate-to-severe obstructive sleep apnea syndrome

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