Impact of novelty and type of material on recognition in healthy older adults and persons with mild cognitive impairment

Belleville, Sylvie; Ménard, Marie-Claude; Lepage, Émilie

doi:10.1016/j.neuropsychologia.2011.06.011

Cited by 32 publications

(37 citation statements)

References 67 publications

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“…On the one hand, several reports of impaired familiarity in MCI and AD patients (Algarabel et al, 2009; Ally, Gold, & Budson, 2009; Didic et al, 2013; Embree, Budson, & Ally, 2012; Wolk et al, 2013; Wolk et al, 2008) are consistent with the prediction that item familiarity should be disrupted very early in the course of Alzheimer's disease due to initial deterioration of the extrahippocampal medial temporal lobe regions on which it depends (Didic et al, 2011). On the other hand, there is contrasting evidence of spared familiarity in MCI and AD, notably in memory tasks for pictures (Embree et al, 2012; O'Connor & Ally, 2010; Westerberg et al, 2013; Westerberg et al, 2006), but also in verbal memory tasks (Anderson et al, 2008; Belleville, Menard, & Lepage, 2011; Genon et al, 2013, 2014; Serra et al, 2010). …”

Section: Discussionmentioning

confidence: 99%

Associative memory and its cerebral correlates in Alzheimer׳s disease: Evidence for distinct deficits of relational and conjunctive memory

et al. 2014

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This study investigated the impact of Alzheimer's disease (AD) on conjunctive and relational binding in episodic memory. Mild AD patients and controls had to remember item-color associations by imagining color either as a contextual association (relational memory) or as a feature of the item to be encoded (conjunctive memory). Patients' performance in each condition was correlated with cerebral metabolism measured by FDG-PET. The results showed that AD patients had an impaired capacity to remember item-color associations, with deficits in both relational and conjunctive memory. However, performance in the two kinds of associative memory varied independently across patients. Partial least square analyses revealed that poor conjunctive memory was related to hypometabolism in an anterior temporal-posterior fusiform brain network, whereas relational memory correlated with metabolism in regions of the default mode network. These findings support the hypothesis of distinct neural systems specialized in different types of associative memory and point to heterogeneous profiles of memory alteration in Alzheimer's disease as a function of damage to the respective neural networks.

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Section: Discussionmentioning

confidence: 99%

Associative memory and its cerebral correlates in Alzheimer׳s disease: Evidence for distinct deficits of relational and conjunctive memory

et al. 2014

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“…Note that three studies examined recollection and familiarity in both healthy aging and aMCI (Anderson et al 2008; Belleville et al 2011; Wolk et al 2013), and two studies compared an aMCI and AD sample to a single healthy older adult control group (Ally et al 2009; Hudon et al 2009). Table 4 shows the number of participants and demographic data for the samples of the healthy aging, aMCI, and AD studies included in the effect size meta-analysis.…”

Section: Methodsmentioning

confidence: 99%

“…However, there is still disagreement about the nature of recollection and familiarity impairments in healthy aging. Some have reported that healthy aging is associated with selective declines in recollection-based episodic memory (Cohn et al 2008; Jennings and Jacoby 1993; 1997; McCabe et al 2009; Parkin and Walter 1992; Wolk et al 2013; Yonelinas 2002), whereas others have found that healthy aging is associated with declines in both recollection- and familiarity-based episodic memory (Belleville et al 2011; Duarte et al 2006; Düzel et al 2011; Friedman et al 2010; Parks 2007; Peters and Daum 2008; Prull et al 2006; Wang et al 2012). …”

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confidence: 99%

The Effects of Healthy Aging, Amnestic Mild Cognitive Impairment, and Alzheimer’s Disease on Recollection and Familiarity: A Meta-Analytic Review

2014

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It is well established that healthy aging, amnestic Mild Cognitive Impairment (aMCI), and Alzheimer’s Disease (AD) are associated with substantial declines in episodic memory. However, there is still debate as to how two forms of episodic memory – recollection and familiarity – are affected by healthy and pathological aging. To address this issue we conducted a meta-analytic review of the effect sizes reported in studies using remember/know (RK), receiver operating characteristic (ROC) and process dissociation (PD) methods to examine recollection and familiarity in healthy aging (25 published reports), aMCI (9 published reports), and AD (5 published reports). The results from the meta-analysis revealed that healthy aging is associated with moderate-to-large recollection impairments. Familiarity was not impaired in studies using ROC or PD methods but was impaired in studies that used the RK procedure. aMCI was associated with large decreases in recollection whereas familiarity only tended to show a decrease in studies with a patient sample comprised of both single-domain and multiple-domain aMCI patients. Lastly, AD was associated with large decreases in both recollection and familiarity. The results are consistent with neuroimaging evidence suggesting that the hippocampus is critical for recollection whereas familiarity is dependent on the integrity of the surrounding perirhinal cortex. Moreover, the results highlight the relevance of method selection when examining aging, and suggest that familiarity deficits might be a useful behavioral marker for identifying individuals that will develop dementia.

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“…was significantly impaired on a YN test for object pictures but performed at normal levels on a 4-alternative FCC test (Holdstock et al, 2002). This dissociation has been replicated in two groups of amnestic Mild Cognitive Impairment (aMCI) patients (Westerberg et al, 2013; Westerberg et al, 2006), a group for whom there is growing evidence of impaired recollection and preserved familiarity, at least for visual stimuli (Anderson et al, 2008; Belleville, Ménard, & Lepage, 2011; Deason, Hussey, Budson, & Ally, 2012; Embree, Budson, & Ally, 2012; Hudon, Belleville, & Gauthier, 2009; O’Connor & Ally, 2010; Schefter et al, 2013; Serra et al, 2010). …”

mentioning

confidence: 91%

Individual differences in forced-choice recognition memory: Partitioning contributions of recollection and familiarity

Migo

Quamme

Holmes

et al. 2014

Quarterly Journal of Experimental Psychology

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In forced-choice recognition memory, two different testing formats are possible under conditions of high target-foil similarity: each target can be presented alongside foils similar to itself (forced-choice corresponding; FCC), or alongside foils similar to other targets (forced-choice non-corresponding; FCNC).Recent behavioural and neuropsychological studies suggest that FCC performance can be supported by familiarity whereas FCNC performance is supported primarily by recollection. In this paper, we corroborate this finding from an individual differences perspective. A group of older adults were given a test of FCC and FCNC recognition for object pictures, as well as standardised tests of recall, recognition and IQ. Recall measures were found to predict FCNC, but not FCC performance, consistent with a critical role for recollection in FCNC only. After the common influence of recall was removed, standardised tests of recognition predicted FCC, but not FCNC performance. This is consistent with a contribution of only familiarity in FCC. Simulations show that a two process model, where familiarity and recollection make separate contributions to recognition, is ten times more likely to give these results than a single-process model. This evidence highlights the importance of recognition memory test design when examining the involvement of recollection and familiarity.

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Impact of novelty and type of material on recognition in healthy older adults and persons with mild cognitive impairment

Cited by 32 publications

References 67 publications

Associative memory and its cerebral correlates in Alzheimer׳s disease: Evidence for distinct deficits of relational and conjunctive memory

Associative memory and its cerebral correlates in Alzheimer׳s disease: Evidence for distinct deficits of relational and conjunctive memory

The Effects of Healthy Aging, Amnestic Mild Cognitive Impairment, and Alzheimer’s Disease on Recollection and Familiarity: A Meta-Analytic Review

Individual differences in forced-choice recognition memory: Partitioning contributions of recollection and familiarity

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