Impact of nonscraping of granulation tissue on outcomes after skin grafting

Krishna, Deepak; Kumar, Shalabh; Sharma, Upendra; Gupta, Deepti

doi:10.4103/ijb.ijb_30_16

Cited by 1 publication

(2 citation statements)

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“…17 Fibrin sealant was shown to promote hemostasis and act as a biological adherent by promoting quick, firm adhesion between the wound bed and the graft. 18,19 In our study, the mean percentage of graft take on postoperative day 15 was higher in the study group as compared with the control group. Fibrin sealant has been seen to result in a higher graft take by Saxena et al, 20 Han et al, 21 Kim et al, 22 Muthukumar et al, 10 Gibran et al 23 and Foster et al 24 reported a comparable graft take between the fibrin group and conventional group (►Table 2).…”

Section: Discussionmentioning

confidence: 41%

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An Outcome Analysis of Fibrin Sealant versus Staples for Fixation of Split-Thickness Skin Grafts

Shuchi,

Gupta,

Sarabahi

2024

Indian J Plast Surg

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Background Skin grafting plays a vital role in post-burn and post-traumatic wound management. Split-thickness skin grafts (STSG) are traditionally fixed using staples or sutures, which have tedious application and their removal necessitates painkillers, medical equipment, and human intervention. As an alternative, fibrin sealant is a biological tissue adhesive, composed of thrombin, calcium, and fibrinogen. Fibrin sealant promotes hemostasis and acts as a biological adherent. Objective The aim of this study was to evaluate the outcomes (graft take, wound healing and complications) of fibrin sealant and staples for STSG fixation. Methods It is a randomized controlled trial on 40 patients with wounds of minimum 400 cm2. Wound area was divided into equal halves and randomly allocated to the study group or control group. In the study group, 4 mL per 200 cm2 of fibrin sealant was sprayed followed by STSG application. In the control group, STSG was fixed with only skin staples. Evaluation was done on postoperative days 3, 5, 15, and 30 for graft take, hematoma/seroma, infection, and complete wound healing. Results The mean graft take was significantly higher (p-value < 0.05) in the study group than in the control group (91 vs. 89%). No seroma or hematoma formation was seen in either group. Complete wound healing was seen in more patients in the study group, but the difference was statistically insignificant. Conclusion Fibrin sealant is an excellent alternative to staples for skin grafting, with the advantage of better graft take and being free of pain that is incurred during staple removal.

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Section: Discussionmentioning

confidence: 41%

“… 17 Fibrin sealant was shown to promote hemostasis and act as a biological adherent by promoting quick, firm adhesion between the wound bed and the graft. 18 19 …”

Section: Discussionmentioning

confidence: 99%