Impact of nanogold morphology on interactions with human serum

A simple galvanic replacement (GR) reaction‐based strategy to create copper‐based bimetallic fabrics for photoreductive catalysis is reported. It is shown that a nanostructured Cu@Fabric can be easily converted into bimetallic Cu‐Au@Fabric and Cu‐Ag@Fabric through a spontaneous electroless process that involves simple exposure of copper fabrics to the aqueous solutions of gold and silver ions. The nanoscale hierarchical ordering of cotton fabrics combined with their high porosity and wettability make them outstanding supports for catalyst recovery and reusability. The deposition of miniscule quantities of expensive noble metals on readily available Cu not only reduces the overall catalyst cost, but also plays a major role in improving the catalyst stability and reusability over several cycles through minimizing Cu oxidation. The synergistic effects of the localized surface plasmon resonance (LSPR) properties of Cu, Au, and Ag allow these bimetallic fabrics into highly active visible light photocatalysts. Mechanistic investigation of the photocatalytic activity provides in‐depth information on the electron transfer processes occurring at the catalyst/ reactant interface, revealing electron transport as the rate‐limiting step, which could be overcome under visible light photoillumination conditions. The outcomes enhance the understanding of template‐supported bimetallic nanostructures for LSPR‐induced photocatalysis applications, offering new potential to design multifunctional fabrics for various applications.

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Section: Characterization Of Cu-m X @Fabricssupporting

confidence: 92%

LSPR‐Induced Catalytic Enhancement Using Bimetallic Copper Fabrics Prepared by Galvanic Replacement Reactions

Anderson

O’Mullane

Gaspera

et al. 2019

Adv Materials Inter

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“…With the development of surface-sensitive spectroscopy techniques, such as Surface Plasmon Resonance (SPR), attenuated total reflection Fourier transform Infrared (ATR-FTIR), Sum Frequency Generation (SFG), Polarization Modulation Infrared Reflectance Absorption Spectroscopy (PM-IRRAS), Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS), Surface Enhanced Raman Spectroscopy (SERS), Circular Dichroism (CD), and X-ray Absorption Spectroscopy (XAS), it is possible to probe into the interactions at the interface. [4][5][6][7][8][9][10][11][12][13] Computational modelling approaches have also been employed to provide atomistic insight into the nature of the interactions between nanoparticles and biomolecules. [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] Yao et al, has reported a combined experimental and theoretical study on the adsorption behavior of l-cystein on gold nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Interaction between organic molecules and a gold nanoparticle: a quantum chemical topological analysis

Tandiana

Van-Oanh²,

Clavaguéra³

2021

Theor Chem Acc

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The ligands at the surface of a gold nanoparticle (GNP) have a significant influence on the optical and physical properties, that may render different functionalities to the GNP. Therefore, there is a need in understanding the nature of the interaction at atomic resolution in order to allow rational design of GNPs with desired physico-chemical properties. The interaction between Au 79 and a series of small organic molecules has been systematically studied at the quantum mechanical level : methane, methanol, formic acid, hydrogen sulfide, benzene, and ammonia. The reactivity of Au 79 has been first analyzed by performing the condensed Fukui analysis to emphasize that the surface of Au 79 is dominated by electrophilic sites, with higher reactivity at the corner and edge atoms. The net charge transfer flowing from the organic molecules towards Au 79 , comes from the electrophilic behaviour of the GNP. Furthermore, the shape of the frontier molecular orbitals of Au 79 and of the incoming organic molecules has been found to dictate the preferred orientation of the adsorption. Several quantum chemical topological analyses of the electron density have been

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“…Interestingly, shapes with planar surfaces have reduced accessibility and therefore less interaction with SA, as demonstrated by Carnovale et al96. In this novel study, the interaction between SA and AuNPs with different geometries was compared, namely AuNSs, AuNRs, AuNPrs and AuNCs.…”

Section: Aunps and Albuminmentioning

confidence: 87%

<p>Capping gold nanoparticles with albumin to improve their biomedical properties</p>

Bolaños

Kogan

Araya

2019

IJN

133

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Nanotechnology is an emerging field which has created great opportunities either through the creation of new materials or by improving the properties of existing ones. Nanoscale materials with a wide range of applications in areas ranging from engineering to biomedicine have been produced. Gold nanoparticles (AuNPs) have emerged as a therapeutic agent, and are useful for imaging, drug delivery, and photodynamic and photothermal therapy. AuNPs have the advantage of ease of functionalization with therapeutic agents through covalent and ionic binding. Combining AuNPs and other materials can result in nanoplatforms, which can be useful for biomedical applications. Biomaterials such as biomolecules, polymers and proteins can improve the therapeutic properties of nanoparticles, such as their biocompatibility, biodistribution, stability and half-life. Serum albumin is a versatile, non-toxic, stable, and biodegradable protein, in which structural domains and functional groups allow the binding and capping of inorganic nanoparticles. AuNPs coated with albumin have improved properties such as greater compatibility, bioavailability, longer circulation times, lower toxicity, and selective bioaccumulation. In the current article, we review the features of albumin, as well as its interaction with AuNPs, focusing on its biomedical applications.

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Impact of nanogold morphology on interactions with human serum

Abstract: Following the synthesis of different shaped gold nanoparticles, their interaction with human serum albumin was studied to reveal shape affects both the affinity and strength of binding.

Cited by 20 publications

References 47 publications

LSPR‐Induced Catalytic Enhancement Using Bimetallic Copper Fabrics Prepared by Galvanic Replacement Reactions

LSPR‐Induced Catalytic Enhancement Using Bimetallic Copper Fabrics Prepared by Galvanic Replacement Reactions

Interaction between organic molecules and a gold nanoparticle: a quantum chemical topological analysis

<p>Capping gold nanoparticles with albumin to improve their biomedical properties</p>

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