Impact of Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio on Long-Term Outcome in Patients Undergoing Percutaneous Coronary Intervention

Matsumoto, Ichiro; Miyake, Yuichi; Mizukawa, Mizuki; Takagi, Yuichiro

doi:10.1253/circj.cj-10-0258

Cited by 29 publications

(21 citation statements)

References 21 publications

(13 reference statements)

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“…In this study, after the exercise program, the TC level was significantly reduced. This result agrees with those of other studies that have reported a decrease in TC 4) . The reason for this is that the blood lipid level, exercise period, age, exercise intensity, body weight, and body composition would change the TC level.…”

Section: Discussionsupporting

confidence: 94%

“…Another study showed that running 24 km in a week significantly decreased triglyceride (TG) and total cholesterol levels (TC); however, the HDL-C level was significantly increased after exercise training 3) . Based on previous research, it has been concluded that athletes may have a higher HDL-C level than normal people because physical training causes increases TC, LDL-C, and TG [4][5][6] . To the best of our knowledge, there have been many studies focusing on the changes of lipoprotein associated with adult diseases and the results of the present study further substantiate the findings of these other studies.…”

Section: Introductionmentioning

confidence: 99%

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The Effect of Bicycle Ergometer Training on Serum Lipids Levels of Obese Middle School Students

Seo

Cho

2011

J Phys Ther Sci

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Abstract.[Purpose] The purpose of this study was to examine the changes of the total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) in the serum of obese middle school students after bicycle ergometer training. [Subjects and Methods] A total of 20 middle school students who had more than 21 % body fat were recruited for this study. They were randomly assigned into one of two groups (exercise=10, control=10). The exercise group performed bicycle ergometer exercise three days per week for 40 minutes for eight weeks. Student's t-test was used to compare differences between the two groups.[Results] There was a significant decrease in TC in exercise group compared to the control. There was a significant decrease in TG in exercise group compared to the control. There was a significant increase in HDL-C and a significant decrease in LDC-C after the bicycle ergometer exercise program.[Conclusion] The results indicate that 8 weeks of bicycle exercise may improve the obesity of middle school students. Therefore, it is recommended that a physical training program is needed for youth to provide them with a healthy life.

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Section: Discussionsupporting

confidence: 94%

Section: Introductionmentioning

confidence: 99%

The Effect of Bicycle Ergometer Training on Serum Lipids Levels of Obese Middle School Students

Seo

Cho

2011

J Phys Ther Sci

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“…31 In addition, ratios of LDL-C/ HDL-C and TG/HDL-C, like HDL-C, could determine the risk of mortality only in normal/underweight patients. 32 These conflicting results were also noted in a Japanese CAD cohort from the CREDO-Kyoto registry in which hyperlipidemia did not increase the death odd after first coronary revascularization. 33 Similarly, most of the present patients underwent coronary angiography for the first time since the index catheterization lab was set up after 1993.…”

Section: Discussionmentioning

confidence: 97%

Low High-Density Lipoprotein Cholesterol and Low/Normal Body Mass Index Are Associated With Increased Mortality in Coronary Artery Disease Patients in Taiwan

Lin

et al. 2013

Circ J

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“…Recent studies conducted in Japan have suggested the L/H ratio as a predictor of clinical outcomes in patients after percutaneous coronary intervention, 33 and in the general population. 34 Functional improvement observed in the present study corresponded well with the recent finding by Otagiri et al, 35 who found beneficial vascular structural changes, including a significant reduction of lipid components of the coronary plaque, in Japanese patients with ACS following early administration of low-dose rosuvastatin (2.5 mg/day up to 5 mg/day) for 6 months.…”

Section: Other Drugsmentioning

confidence: 99%

Low-Dose Rosuvastatin Improves Arterial Stiffness in High-Risk Japanese Patients With Dyslipdemia in a Primary Prevention Group - A Comparison With Fluvastatin -

Hongo

Kumazaki

Izawa

et al. 2011

Circ J

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Background:The treatment effects of rosuvastatin on arterial stiffness were assessed and compared to those of fluvastatin in high-risk Japanese patients with dyslipidemia in a primary prevention group. Methods and Results:Patients were randomly assigned to either 2.5-5 mg/day of rosuvastatin (Group A) or 20-40 mg/day of fluvastatin (Group B) and followed up for 12 months. In Group A (n=38), there was a progressive reduction in brachial-ankle pulse wave velocity (baPWV) along with a decrease in the low-density lipoprotein cholesterol/ high-density lipoprotein cholesterol (L/H) ratio and high-sensitivity C-reactive protein (hsCRP), and the change in baPWV correlated significantly with that of the L/H ratio and that of hsCRP after rosuvastatin treatment. In Group B (n=37), although fluvastatin achieved a significant improvement in baPWV, L/H ratio, and hsCRP, baPWV was significantly greater than that in Group A and showed a significant correlation with that of hsCRP alone after fluvastatin treatment. In a subgroup of patients (n=26), switching from fluvastatin to rosuvastatin further improved baPWV and the L/H ratio without altering hsCRP after 12 months. Conclusions:Low-dose rosuvastatin would be more effective than fluvastatin in improving arterial stiffness in highrisk Japanese patients with dyslipidemia. The results suggest that improvement in arterial stiffness by rosuvastatin mainly depends on its strong lipid-lowering effects, whereas that by fluvastatin is strongly dependent on the pleiotropic effects, especially an anti-inflammatory action. (Circ J 2011; 75: 2660 - 2667

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Impact of Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio on Long-Term Outcome in Patients Undergoing Percutaneous Coronary Intervention

Cited by 29 publications

References 21 publications

The Effect of Bicycle Ergometer Training on Serum Lipids Levels of Obese Middle School Students

The Effect of Bicycle Ergometer Training on Serum Lipids Levels of Obese Middle School Students

Low High-Density Lipoprotein Cholesterol and Low/Normal Body Mass Index Are Associated With Increased Mortality in Coronary Artery Disease Patients in Taiwan

Low-Dose Rosuvastatin Improves Arterial Stiffness in High-Risk Japanese Patients With Dyslipdemia in a Primary Prevention Group - A Comparison With Fluvastatin -

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