Impact of lifestyle‐related disease on conversion and reversion in patients with mild cognitive impairment: after 12 months of follow‐up

Abstract

The absence of lipid abnormality at baseline may contribute to reversion in patients with MCI. The presence of multiple LSRD was associated with cognitive decline. Our results highlight the contribution of multiple LSRD on increasing conversion and decreasing reversion in patients with MCI. Copyright © 2015 John Wiley & Sons, Ltd.

Potential Benefits of Physical Activity in MCI and Dementia

“…One pathway by which physical activity impacts the brain is via the prevention or better management of cardiovascular risk factors (e.g., diabetes, hypertension, hyperlipidemia, and obesity). In fact, among those with MCI, presence of cardiovascular risk factors is associated with increased likelihood of progression to dementia [38]. Cardiovascular risk factors are associated with various changes to brain health.…”

Progression and predictors of mild cognitive impairment in Chinese elderly: A prospective follow‐up in the Shanghai Aging Study

“…Previous community-based studies also reported the predictors of MCI progression, e.g., older age, shorter years of school, depression, with history of diabetes or stroke, African Americans and Hispanic, and baseline MMSE score [8] , [11] , [12] , [13] , [14] , [22] , [23] , [24] . Other predictors were reported mostly from hospital-based studies, such as female gender [25] , APOE genotype [26] , white matter hyperintensities [27] , lifestyle-related disease (hypertension, type II diabetes mellitus, and lipid abnormality) [28] , high plasma C-reactive protein level [29] , orthostatic blood pressure behavior [30] , and unstable body mass index [31] . Our study explored the older age, APOE ε4 allele positive and low MMSE score at baseline, but not the gender and education years, were the independent risk predictors to dementia.…”

P1‐395: Progression and Predictors of Mild Cognitive Impairment in Chinese Elderly: A Prospective Follow‐Up in The Shanghai Aging Study

“…Previous community-based studies also reported the predictors of MCI progression, e.g., older age, shorter years of school, depression, with history of diabetes or stroke, African Americans and Hispanic, and baseline MMSE score [8,[11][12][13][14][22][23][24]. Other predictors were reported mostly from hospital-based studies, such as female gender [25], APOE genotype [26], white matter hyperintensities [27], lifestyle-related disease (hypertension, type II diabetes mellitus, and lipid abnormality) [28], high plasma C-reactive protein level [29], orthostatic blood pressure behavior [30], and unstable body mass index [31]. Our study explored the older age, APOE ε4 allele positive and low MMSE score at baseline, but not the gender and education years, were the independent risk predictors to dementia.…”