“…The infected fish may mount a protective immune response (Bauer, 1953; Burkart, Clark, & Dickerson, 1990; Buschkiel, 1910; Dickerson & Clark, 1998; Goven, Dawe, & Gratzek, 1980; Hines & Spira, 1974; Moreira, Shoemaker, Zhang, & Xu, 2016; Sigh & Buchmann, 2001; Wang, Yu, Zhang, & Xu, 2019), but the experimental vaccines investigated so far (Burkart et al., 1990; He et al., 1997; Jørgensen et al, 2017; Ling, Sin, & Lam, 1993; Martins, Xu, Shoemaker, & Klesius, 2011; Wang, Clark, Noe, & Dickerson, 2002; Xu, Zhang, Shoemaker, & Beck, 2019) have not yet resulted in a marketable protective formulation. A number of chemotherapeutants have been successfully applied in the laboratory (Al‐Jubury et al., 2018; Picon‐Camacho, Marcos‐Lopez, & Shinn, 2012), but at farm level frequent usage of formalin, peracetic acid, sodium percarbonate and hydrogen peroxide remains the preferred control strategy (Heinecke & Buchmann, 2009; Meinelt et al., 2009; Rach, Gaikowski, & Ramsay, 2000). A genetic component associated with susceptibility and resistance to infection has been suggested in rainbowfish (Gleeson, McCalum, & Owens, 2000), leaving relevant possibilities for genetic selection of disease‐resistant strains.…”