Impact of hidradenitis suppurativa on work loss, indirect costs and income

Tzellos, Thrasyvoulos; Yang, Hongbo; Mu, Fan; Calimlim, Brian; Signorovitch, J.

doi:10.1111/bjd.17101

Cited by 66 publications

(72 citation statements)

References 18 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a US claims database analysis, newly diagnosed HS patients had significantly slower income growth and higher risk of leaving the workforce compared with controls. General HS patients had more total work loss days, higher annual total indirect costs, and lower annual income compared with controls [20].…”

Section: Working Disabilitymentioning

confidence: 85%

“…Association with cardiovascular disease risk factors: obesity, smoking, hypertriglyceridemia, low HDL, diabetes, metabolic syndrome [9] Increased frequency of subclinical atherosclerosis [14] Increased risk of adverse cardiovascular outcomes [16] Need for screening for modifiable cardiovascular risks Avoid treatments with potential negative impact on cardiovascular disease risk factors, e.g., acitretin Implement weight loss strategies Association with slower income growth, higher risk of leaving the workforce, more total work loss days, higher annual total indirect costs and lower annual income [17][18][19][20] HS patients have unmet disease management needs…”

Section: Comorbiditiesmentioning

confidence: 99%

See 1 more Smart Citation

Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice

Tzellos

Zouboulis

2020

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Hidradenitis suppurativa (HS) is a chronic, recurrent skin inflammatory disease associated with a variety of comorbidities, like reduced quality of life, metabolic syndrome, sexual dysfunction, working disability, axial spondyloarthritis, inflammatory bowel disease, depression, and anxiety. Like psoriasis, HS patients have been found to have higher risk of cardiovascular death and suicide risk. Clinicians should be informed about these comorbidities so that appropriate screening is implemented. All this evidence suggests that for such a chronic, multi-comorbid disease, the use of validated outcomes to assess severity and effect of treatment, along with the use of clinically important patient reported outcomes, is essential. The potential of available treatments to negatively and positively affect these comorbidities should also be taken into account when designing treatment strategies. This review provides an outline of important HS comorbidities with emphasis on possible implications for daily clinical practice.

show abstract

Section: Working Disabilitymentioning

confidence: 85%

Section: Comorbiditiesmentioning

confidence: 99%

Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice

Tzellos

Zouboulis

2020

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

show abstract

“…14,41 It creates of course some serious consequences for a home budget and explains that HS is associated with a significant financial impact on both patients' but also their partners' economic status, especially if they are sharing a common home budget. 41 It is not surprising, that because partners of HS patients are often involved in caregiving, their QoL may be indirectly impaired in multiple ways. As chronic disease that requires continuous skincare and causes a sequence of psychologically devastating complications, HS can have an extremely onerous impact on cohabitants as well.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial burden of Hidradenitis Suppurativa patients’ partners

Włodarek

Głowaczewska

Matusiak

et al. 2020

Acad Dermatol Venereol

View full text Add to dashboard Cite

Background Hidradenitis suppurativa is a debilitating disease related to a great psychosocial burden in affected patients and subsequently also people around them. Patients' partners as caregivers may indirectly experience wide range of devastating effects of the disease on their emotional and social life. Objective The purpose of this study was to determine the QoL impairment in HS patients' partners and to identify its aspects that are affected the most. Correlation between QoL burden and disease severity, duration, sex, age and smoking was also assessed. Methods A total of 50 HS sufferers were assessed according to disease severity and their partners' QoL was determined using the Family Dermatology Life Quality Index questionnaire. Results The mean FDLQI for patients' partners was 8.7 AE 6.8 points, indicating generally a moderate effect of HS on their life. Quality of partners' life correlated significantly with disease severity but no correlation was found according to other factors. Conclusion Hidradenitis suppurativa is a highly psychologically devastating disease not only for patients but also for their partners. It occurred to diminish partners' QoL mostly by increasing daily expenditure but also other problems were often reported. Clinicians should be aware of these psychosocial implications, in order to provide optimal therapy of HS affected families by a multidisciplinary specialized management addressing both, patients and their cohabitants simultaneously.

show abstract

“…Although limited, the knowledge of the direct impact of HS on work productivity indicates a mean absence from work of 33.6 days annually . Further, a retrospective cohort study among employed patients with HS in the United States showed significantly lower annual income ($54 925 vs. $62 357), slower annual income growth ($324 less per year), and higher risk of leaving the workforce (adjusted hazard ratio 1.65, 95% confidence interval 1.45–1.88) compared with controls …”

Section: Introductionmentioning

confidence: 99%

Work productivity and activity impairment in patients with hidradenitis suppurativa: a cross‐sectional study

2019

View full text Add to dashboard Cite

Background The understanding of absenteeism, presenteeism, and impairments in daily activities among patients with hidradenitis suppurativa (HS) is limited. We examined the impact of disease-specific factors of HS on work and daily life among a cohort of outpatients in a tertiary hospital setting.Methods Consecutive patients with HS were clinically evaluated and completed the Work Productivity and Activity Impairment (WPAI) questionnaire modified for HS. Results A total of 100 patients were included. Among 57 (57.0%) patients who were employed, 21.2% reported missing work, and 60.4% reported loss of work productivity during the preceding week as a result of HS. The overall work productivity was reduced by 26.6%. Seventy-two percent reported daily activity impairment, averaging 32.7% reduction in daily activities. Moderate to strong correlations were observed between reduction in quality of life and the WPAI outcomes; presenteeism, overall work impairment, and activity impairment (r = 0.50-0.77). There were moderate correlations between disease severity and the same outcomes (r = 0.35-0.46). The mean rank of activity impairment among patients with Hurley stage I was 34.8, 60.1 for Hurley stage II, and 64.0 for Hurley stage III, P < 0.0001. Unemployed patients had higher activity impairment compared with employed patients (mean rank: 61.0 vs. 42.6, P = 0.001).Conclusion There are considerable rates of presenteeism, overall work impairment, and activity impairment in HS patients. Presenteeism, loss of overall work productivity, and activity impairment are positively correlated with greater disease severity and reduction in quality of life.

show abstract

Impact of hidradenitis suppurativa on work loss, indirect costs and income

Abstract: Patients with newly diagnosed HS and general patients with HS experienced a greater indirect burden than matched controls.

Cited by 66 publications

References 18 publications

Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice

Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice

Psychosocial burden of Hidradenitis Suppurativa patients’ partners

Work productivity and activity impairment in patients with hidradenitis suppurativa: a cross‐sectional study

Contact Info

Product

Resources

About